05/13/2026
If you have tried antidepressants that did not work, you may have been told to give it more time or try another medication.
For many people, standard antidepressants that target serotonin are helpful. But for others, different pathways in the brain may be involved.
Treatments like Spravato® and ketamine work on the glutamate system, which is one reason they can help when other options have not.
It is not that anything is wrong with you. Sometimes it means a different approach is needed.
If you’ve tried multiple antidepressants and still feel stuck, our team is here to help you explore what options may be right for you.