Rising Star Integrative Health Services

02/15/2026

02/13/2026

This!

You’ve heard that methylated folate is critical for MTHFR.

But then you start supplementing…

…and instead of feeling better, you feel worse:

• Racing thoughts
• Panic after taking methylated B’s
• Trouble winding down
• Sleep issues
• Mood swings or emotional reactivity
• Overreaction to normal stress

Why???

Folate Isn’t Just Fuel, It’s a Spark

Folate feeds methylation → and methylation accelerates neurotransmitter processing.

When you suddenly add more fuel to that fire (via 5-MTHF or folinic acid)…
📈You increase the turnover of dopamine, norepinephrine, and estrogen.

If your clearance enzymes are underperforming,
😅 things get messy:

COMT: clears dopamine, epinephrine, and estrogen
MAOA: clears serotonin, dopamine, norepinephrine

If either is sluggish due to genetics, stress, or nutrient depletion, methylation support builds pressure without release.

❗ Who’s Most At Risk?
Slow COMT variants (like COMT V158M)
Fast MAOA variants → burn through serotonin quickly
People under chronic stress → high cortisol competes for COMT
Those with low magnesium, riboflavin, or SAMe

It’s not the folate—it’s the traffic jam downstream.

💬 Comment “METHYLATE” to get more information on how to best use methylated folate and avoid methylation overwhelm. Also receive alternatives (Methyl-free) versions of your favorite supplements.

02/10/2026

02/09/2026

| Check out my links to (Rising Star Integrative Health Services: Appointments, Rising Star Apothecary: Supplements & Labs, Troscriptions® Methylene Blue & More: Email me to order!).

02/08/2026

02/07/2026

02/05/2026

02/02/2026

Yes!

01/27/2026

01/27/2026

Neutralizing Asthma, Allergies & Histamine

“Vitamin C in sufficient quantity stops asthma attacks, colds, and hay fever. It acts as nature’s own antihistamine.”
— Dr. Frederick Klenner, M.D.

From an orthomolecular perspective, asthma and allergic reactions are closely tied to histamine imbalance and oxidative stress. Vitamin C plays a central role by directly neutralizing histamine and stabilizing the inflammatory response. When vitamin C levels are low, histamine rises. When ascorbate is restored, symptoms often calm.

Therapeutic Vitamin C dosing (titrated to bowel tolerance):
• Children: 6,000–10,000 mg daily, divided doses
• Adults: 10–20 grams daily, divided doses

Bowel tolerance is the body’s natural feedback mechanism and remains the safest guide for individualized dosing.

This is not suppression — it is biochemical regulation.

Learn more about nutrient-based approaches to histamine regulation and terrain restoration here:
https://www.instituteintegrativebiomedicine.com/link/yryprL