09/15/2021
Unlike other tissue engineering tactics, acoustics position the heart cells in a tight configuration that closely resembles natural cardiac tissue, turning the resulting, beating blob into something valuable for medicine.
Wu and Demirci think acoustic engineering could help foster more realistic cardiac disease modeling and drug screening. More distantly, but still on the horizon, the pair even see their generated tissue as an option for heart patches in patients who have weak cardiac walls or have damage from a heart attack.
Next, Demirci and Wu say that they plan to add vascularization — conduits that carry blood and oxygen to various parts of an organ — to make their generated heart tissue even more realistic.
While listening to a string quartet play over recordings of plasma waves captured in outer space and converted into sound, neurologist Josef Parvizi, MD, PhD, dreamed up a symphony of his own. If you can turn signals from space into sound, perhaps you could turn brain waves into sound too, he thought.
So Parvizi sent an out-of-the-blue email to Christopher Chafe, a composer with expertise in converting atypical data sets into music, and explained his vision. Parvizi, professor of neurology, describes what happened next: “A crazy music professor and a crazy neurologist decided to collaborate on a strange idea.” Chafe is the director of Stanford’s Center for Computer Research in Music and Acoustics.
After several years of refining, the idea developed into something that Parvizi has dubbed the brain stethoscope.
Research at Stanford University is finding acoustics to create new heart tissue!
This image shows the ‘cymatics’, or geometric patterns created in heart cells when applying various sounds. In bio-acoustic sound medicine, is taught that sounds are imprinting every cell and science continues to prove this ancient axiom.
Cardiologist Sean Wu, MD, PhD and Utkan Demirci, PhD, an acoustic bio-engineer use acoustics to manipulate heart cells into intricate patterns. A simple change in frequency and amplitude puts the cells in motion, guides them to a new position and holds them in place. Acoustics can create a form that resembles natural cardiac tissue. With sound they can create new tissue to replace parts of damaged hearts. Acoustics can be used in reconstructing other organ tissue and blood vessels.
Sounds are use to create and harmonize, as well as clean and release. Both principles are used in science using high precision acoustical generators. The same principles can be applied safely by individuals using non-invasive, natural harmonic sounds, such as our voices and acoustic instruments.
Here is a link to the Stanford study: https://stanmed.stanford.edu/listening/innovations-helping-harness-sound-acoustics-healing.html?fbclid=IwAR33XAbh5DTKSwmnY0Rh49WBBABKouZfokbG3A09_DV7i_aoGyH6qlzknds