12/14/2025
Long periods of stress weaken the immune system's capacity to fight off illness over time. If stress never subsides, and the body stays in physiological stress response for too long, the body starts to think that the immune system is the thing that is sick, and therefore it begins to target itself.
The immune system is not sick, but is in fact responding appropriately to the stressors in the environment...it's the environment itself that is sick. This is an appropriate response of the body to stress for a moment, not for a lifetime.
If you aren't able to move out of stress response, the body can't heal and the nerves begin to fray and deaden over time like a power cord without a sheath, which in turn causes nervous system dysfunction and, eventually, autoimmune conditions. Once this occurs, the body has identified the source of the stressor: the nervous system itself. And so begins the planning of a coordinated attack inward to eliminate the threat, with the body shutting systems down and taking processes offline, one by one.
Symptom relief is necessary to get to the safety one needs to start doing the heavy lifting of detoxifying one's environment of chronic stress. This is the only way to calm the nervous system enough to allow it to rest so that it can alleviate the effects of autoimmune conditions.
It is IMPERATIVE that patients have enough medical and holistic support during this process to bridge the gap between what the body needs (safety) and ways to get that (interventions for symptoms relief such as meds, emotional support, self-care, social/cultural systems, etc).
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Chronic Stress Linked to Higher Risk of Autoimmune Diseases, Study Finds.
A new large-scale study suggests that people diagnosed with stress-related disorders, including PTSD, may face a significantly increased risk of developing autoimmune diseases. Researchers tracked over 100,000 individuals with stress disorders and found they were more likely to develop conditions such as lupus, Crohn’s disease, and rheumatoid arthritis compared to their siblings and the general population.
The association was particularly strong in younger patients, highlighting that early psychological trauma could contribute to immune system dysfunction later in life. Interestingly, the study also found that patients with PTSD who were treated with SSRIs—a common class of antidepressants—showed a reduced risk of developing autoimmune diseases.
While the research is observational and does not establish direct causation, it underscores the growing understanding that mental and physical health are closely linked. Experts are calling for further studies to determine whether early mental health interventions could help prevent autoimmune conditions.
Source: Song, H., Fang, F., Tomasson, G., et al. (2018). Association of Stress-Related Disorders With Subsequent Autoimmune Disease. JAMA, 319(23), 2388–2400.