International Perfusion Association

International Perfusion Association The Internal Perfusion Association is a 501C3 non-profit corporation dedicated to mission work.

Normothermic regional perfusion (NRP) is reshaping controlled donation after circulatory death (cDCD) liver transplantat...
02/07/2026

Normothermic regional perfusion (NRP) is reshaping controlled donation after circulatory death (cDCD) liver transplantation. By restoring oxygenated blood flow after death declaration, NRP reduces ischemia-reperfusion injury, lowers rates of early allograft dysfunction and biliary complications, and delivers graft and patient survival comparable to donation after brain death.

Normothermic regional perfusion (NRP) is reshaping controlled donation after circulatory death (cDCD) liver transplantation. By restoring oxygenated blood flow after death declaration, NRP reduces ischemia-reperfusion injury, lowers rates of early allograft dysfunction and biliary complications, and...

Limb ischaemia is a serious complication of veno-arterial extracorporeal membrane oxygenation (V-A ECMO). This systemati...
02/06/2026

Limb ischaemia is a serious complication of veno-arterial extracorporeal membrane oxygenation (V-A ECMO). This systematic review and meta-analysis of 17 studies involving 2,812 adults found a pooled limb ischaemia incidence of 16.9%.

Limb ischaemia is a serious complication of veno-arterial extracorporeal membrane oxygenation (V-A ECMO). This systematic review and meta-analysis of 17 studies involving 2,812 adults found a pooled limb ischaemia incidence of 16.9%. Peripheral arterial disease, unsuccessful percutaneous cannulation...

This systematic review and meta-analysis evaluated whether ex vivo lung perfusion (EVLP) improves outcomes in donation a...
02/05/2026

This systematic review and meta-analysis evaluated whether ex vivo lung perfusion (EVLP) improves outcomes in donation after circulatory death (DCD) lung transplantation.

This systematic review and meta-analysis evaluated whether ex vivo lung perfusion (EVLP) improves outcomes in donation after circulatory death (DCD) lung transplantation. Across five observational studies including 654 patients, EVLP showed no significant differences in grade 3 primary graft dysfunc...

This retrospective cohort study from a Malaysian tertiary cardiac center compares Custodial-HTK cardioplegia with conven...
02/05/2026

This retrospective cohort study from a Malaysian tertiary cardiac center compares Custodial-HTK cardioplegia with conventional blood cardioplegia in elective on-pump cardiac surgery.

This retrospective cohort study from a Malaysian tertiary cardiac center compares Custodial-HTK cardioplegia with conventional blood cardioplegia in elective on-pump cardiac surgery. Although Custodial-HTK was preferentially used in higher-risk and more complex cases with lower baseline LVEF and lon...

This comprehensive review examines alternative crystalloid and whole-blood base solutions for del Nido cardioplegia, inc...
01/31/2026

This comprehensive review examines alternative crystalloid and whole-blood base solutions for del Nido cardioplegia, including normal saline, lactated Ringer’s, plain Ringer’s, Isolyte S, Ionosteril, and whole blood.
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This comprehensive review examines alternative crystalloid and whole-blood base solutions for del Nido cardioplegia, including normal saline, lactated Ringer’s, plain Ringer’s, Isolyte S, Ionosteril, and whole blood. Drawing on experimental models, randomized trials, and clinical studies, the ar...

This meta-analysis evaluated 12 randomized trials (908 patients) comparing 6% hydroxyethyl starch (HES) 130/0.4 with 5% ...
01/31/2026

This meta-analysis evaluated 12 randomized trials (908 patients) comparing 6% hydroxyethyl starch (HES) 130/0.4 with 5% albumin during cardiopulmonary bypass in cardiac surgery. Most outcomes—including blood loss, transfusion rates, ICU stay, hospital stay, and mortality—were similar between groups.

This meta-analysis evaluated 12 randomized trials (908 patients) comparing 6% hydroxyethyl starch (HES) 130/0.4 with 5% albumin during cardiopulmonary bypass in cardiac surgery. Most outcomes—including blood loss, transfusion rates, ICU stay, hospital stay, and mortality—were similar between gro...

This retrospective study examined over 5,500 patients undergoing cardiac surgery to assess whether higher doses of trane...
01/28/2026

This retrospective study examined over 5,500 patients undergoing cardiac surgery to assess whether higher doses of tranexamic acid (TXA) reduce postoperative delirium (PD). Despite TXA’s known anti-inflammatory effects and role in stabilizing the blood-brain barrier, the study found no significant dose-dependent reduction in PD.

This retrospective study examined over 5,500 patients undergoing cardiac surgery to assess whether higher doses of tranexamic acid (TXA) reduce postoperative delirium (PD). Despite TXA’s known anti-inflammatory effects and role in stabilizing the blood-brain barrier, the study found no significant...

This retrospective study examined over 5,500 patients undergoing cardiac surgery to assess whether higher doses of trane...
01/28/2026

This retrospective study examined over 5,500 patients undergoing cardiac surgery to assess whether higher doses of tranexamic acid (TXA) reduce postoperative delirium (PD). Despite TXA’s known anti-inflammatory effects and role in stabilizing the blood-brain barrier, the study found no significant dose-dependent reduction in PD.

This retrospective study examined over 5,500 patients undergoing cardiac surgery to assess whether higher doses of tranexamic acid (TXA) reduce postoperative delirium (PD). Despite TXA’s known anti-inflammatory effects and role in stabilizing the blood-brain barrier, the study found no significant...

This in-vitro study evaluates the optimal timing for discontinuing cardiotomy suction during cardiopulmonary bypass (CPB...
01/28/2026

This in-vitro study evaluates the optimal timing for discontinuing cardiotomy suction during cardiopulmonary bypass (CPB) when reversing heparin anticoagulation with protamine sulfate. Using porcine blood samples, the researchers assessed activated clotting times (ACTs) after administering a protamine test dose (PTD) and 1/3 of the full dose.

This in-vitro study evaluates the optimal timing for discontinuing cardiotomy suction during cardiopulmonary bypass (CPB) when reversing heparin anticoagulation with protamine sulfate. Using porcine blood samples, the researchers assessed activated clotting times (ACTs) after administering a protami...

This study evaluated the renal impact of two cardioplegic solutions—HTK and DelNido—in pigs undergoing cardiac arrest. D...
11/20/2025

This study evaluated the renal impact of two cardioplegic solutions—HTK and DelNido—in pigs undergoing cardiac arrest. Despite DelNido showing better electrolyte and hemoglobin stability, both solutions induced comparable levels of renal injury.

This study evaluated the renal impact of two cardioplegic solutions—HTK and DelNido—in pigs undergoing cardiac arrest. Despite DelNido showing better electrolyte and hemoglobin stability, both solutions induced comparable levels of renal injury. Biomarkers (NGAL, FABP-1, cystatin C), histologica...

We are proud to share the remarkable success of our recent cardiac surgery mission to Cuenca, Ecuador, a collaborative e...
10/25/2025

We are proud to share the remarkable success of our recent cardiac surgery mission to Cuenca, Ecuador, a collaborative effort between our Ecuador Mission team and Massachusetts General Hospital (Harvard Medical School).

We are proud to share the remarkable success of our recent cardiac surgery mission to Cuenca, Ecuador, a collaborative effort between our Ecuador Mission team and Massachusetts General Hospital (Harvard Medical School). This initiative brought together an exceptional team of healthcare professionals...

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