International Perfusion Association

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This systematic review examines anticoagulation monitoring during cardiopulmonary bypass in patients with antiphospholip...
04/23/2026

This systematic review examines anticoagulation monitoring during cardiopulmonary bypass in patients with antiphospholipid syndrome, a high-risk prothrombotic condition that can make activated clotting time unreliable. Across 17 studies and 62 patients, ACT, Hepcon, anti-Xa, and viscoelastic testing were used inconsistently.

This systematic review examines anticoagulation monitoring during cardiopulmonary bypass in patients with antiphospholipid syndrome, a high-risk prothrombotic condition that can make activated clotting time unreliable. Across 17 studies and 62 patients, ACT, Hepcon, anti-Xa, and viscoelastic testing...

This case report describes a 69-year-old woman who developed thrombotic obstruction of a mitral bioprosthesis while rece...
04/14/2026

This case report describes a 69-year-old woman who developed thrombotic obstruction of a mitral bioprosthesis while receiving VA-ECMO with left ventricular venting after complex multivalve surgery. Delayed anticoagulation, prosthetic material, altered intracardiac flow, and postoperative bleeding likely combined to trigger thrombosis.

This case report describes a 69-year-old woman who developed thrombotic obstruction of a mitral bioprosthesis while receiving VA-ECMO with left ventricular venting after complex multivalve surgery. Delayed anticoagulation, prosthetic material, altered intracardiac flow, and postoperative bleeding li...

This single-center retrospective study of 381 adult heart transplants found that prolonged oxygen extraction ratio, or O...
04/12/2026

This single-center retrospective study of 381 adult heart transplants found that prolonged oxygen extraction ratio, or O2ER, above 0.20 during cardiopulmonary bypass was linked to higher post-transplant morbidity and early mortality.

This single-center retrospective study of 381 adult heart transplants found that prolonged oxygen extraction ratio, or O2ER, above 0.20 during cardiopulmonary bypass was linked to higher post-transplant morbidity and early mortality. O2ER outperformed low indexed oxygen delivery alone in predicting....

This case report describes the first known heart-liver-kidney transplant for AL amyloidosis using organs recovered from ...
04/09/2026

This case report describes the first known heart-liver-kidney transplant for AL amyloidosis using organs recovered from a donation-after-circulatory-death donor with thoracoabdominal normothermic regional perfusion.

This case report describes the first known heart-liver-kidney transplant for AL amyloidosis using organs recovered from a donation-after-circulatory-death donor with thoracoabdominal normothermic regional perfusion. A 40-year-old man with terminal multiorgan AL amyloidosis underwent sequential heart...

This retrospective Malaysian cohort study examined 6,779 adult cardiac surgery patients and found that 4.5% developed po...
04/07/2026

This retrospective Malaysian cohort study examined 6,779 adult cardiac surgery patients and found that 4.5% developed postoperative acute kidney injury requiring dialysis. Risk was higher in patients with chronic kidney disease, urgent surgery, diabetes, reoperation, and longer ICU stay.

This retrospective Malaysian cohort study examined 6,779 adult cardiac surgery patients and found that 4.5% developed postoperative acute kidney injury requiring dialysis. Risk was higher in patients with chronic kidney disease, urgent surgery, diabetes, reoperation, and longer ICU stay. Dialysis-re...

This guideline article argues that extracorporeal life support device testing should follow standardized in-vitro protoc...
04/05/2026

This guideline article argues that extracorporeal life support device testing should follow standardized in-vitro protocols so results can be reproduced, compared across research groups, and translated more effectively into practice.

This guideline article argues that extracorporeal life support device testing should follow standardized in-vitro protocols so results can be reproduced, compared across research groups, and translated more effectively into practice. It outlines reporting criteria, relevant ISO standards, preferred....

This retrospective single-center study evaluated 9,792 children aged 14 years or younger undergoing cardiac surgery with...
04/02/2026

This retrospective single-center study evaluated 9,792 children aged 14 years or younger undergoing cardiac surgery with cardiopulmonary bypass.

This retrospective single-center study evaluated 9,792 children aged 14 years or younger undergoing cardiac surgery with cardiopulmonary bypass. After implementation of a quality-managed, multimodal blood conservation program, matched analysis showed lower PRBC and plasma transfusion rates, smaller....

This retrospective study compared normoxic and hyperoxic reperfusion strategies in 50 patients undergoing elective on-pu...
04/02/2026

This retrospective study compared normoxic and hyperoxic reperfusion strategies in 50 patients undergoing elective on-pump CABG. Although oxygen delivery was similar between groups, normoxic management was associated with lower postoperative myocardial injury, better cardiac index, smaller declines in ejection fraction, and lower oxidative stress.

This retrospective study compared normoxic and hyperoxic reperfusion strategies in 50 patients undergoing elective on-pump CABG. Although oxygen delivery was similar between groups, normoxic management was associated with lower postoperative myocardial injury, better cardiac index, smaller declines....

This multicenter Canadian registry study examined 2,481 patients who underwent aortic arch reconstruction between 2002 a...
04/01/2026

This multicenter Canadian registry study examined 2,481 patients who underwent aortic arch reconstruction between 2002 and 2021, including 374 redo cases after prior open-heart surgery. Despite a higher comorbidity burden, redo surgery was not associated with significantly higher overall operative mortality or major morbidity than primary surgery.

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Artificial intelligence (AI) is transforming adult cardiovascular medicine and surgery by enhancing diagnostics, surgica...
04/01/2026

Artificial intelligence (AI) is transforming adult cardiovascular medicine and surgery by enhancing diagnostics, surgical planning, intraoperative precision, and postoperative monitoring. Tools such as AI-ECG, automated imaging, and predictive analytics improve risk stratification and outcomes.

Artificial intelligence (AI) is transforming adult cardiovascular medicine and surgery by enhancing diagnostics, surgical planning, intraoperative precision, and postoperative monitoring. Tools such as AI-ECG, automated imaging, and predictive analytics improve risk stratification and outcomes. Whil...

This scoping review maps the evidence on ECMO anticoagulation strategies beyond unfractionated heparin. Across 135 inclu...
03/31/2026

This scoping review maps the evidence on ECMO anticoagulation strategies beyond unfractionated heparin. Across 135 included records, direct thrombin inhibitors—especially bivalirudin—were the most studied alternatives, while nafamostat, prostaglandin E1, circuit modifications, anticoagulation-free protocols, and newer monitoring tools remain emerging areas.

This scoping review maps the evidence on ECMO anticoagulation strategies beyond unfractionated heparin. Across 135 included records, direct thrombin inhibitors—especially bivalirudin—were the most studied alternatives, while nafamostat, prostaglandin E1, circuit modifications, anticoagulation-fr...

This geospatial cross-sectional study examined how access to pediatric extracorporeal membrane oxygenation varies across...
03/30/2026

This geospatial cross-sectional study examined how access to pediatric extracorporeal membrane oxygenation varies across U.S. states and Pediatric Emergency Referral Regions. Researchers identified 258 pediatric ECMO centers and 169 ECPR centers, finding major differences in direct access, especially in rural areas.
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This geospatial cross-sectional study examined how access to pediatric extracorporeal membrane oxygenation varies across U.S. states and Pediatric Emergency Referral Regions. Researchers identified 258 pediatric ECMO centers and 169 ECPR centers, finding major differences in direct access, especiall...

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