Jali Medical

Established in 1991, Jali Medical is a company at the cutting edge of the emerging field of non-invasive brain stimulation.

We are proud to be the US distributor for the best magnetic and electrical nerve stimulation products available.

08/21/2025

Researchers make some noise with a silent stroke tool

Author: Steven Barlow

One of the most common strokes is termed “ischemic stroke.” It obstructs blood flow to the brain, depriving it of the oxygen it needs to survive. Ischemic stroke is the leading cause of long-term disability and fifth-leading cause of death in the U.S. “They have this phrase in the stroke literature, ‘time is brain.’

Using brain imaging, Barlow and his colleagues have found that their technology can increase brain blood flow up to 20 percent. In animal studies, it forced the brain to reroute blood supply to affected areas to protect the cells.

To read full article, click: https://jalimedical.com/ -bulletin

At the University of Nebraska–Lincoln, Steven Barlow’s research team is developing solutions for front-line treatment after a stroke. It’s all a question of blood flow.

This innovative device, the Galileo Pneumatic Tactile Stimulator, will be showcased at the Society for Neuroscience 2025 in San Diego, November 16–19. Stop by Jali Medical, Inc. at Booth 922 for live demonstrations and discover how Galileo is helping advance neuroscience research.

Join us at and explore how Galileo can support your work in understanding and treating brain disorders.

07/31/2025

Boosting working memory in the elderly: driving prefrontal theta–gamma coupling via repeated neuromodulation

Authors: Lukas Diedrich, Hannah I Kolhoff, Clara Bergmann, Mathias Bähr, Andrea Antal

DOI: https://doi.org/10.1007/s11357-024-01272-3

Our study provides evidence for targeted improvement of WM in older adults via repeated non-invasive neuromodulation using tACS. Specifically, driving prefrontal theta–gamma coupling in a treatment-like 16-day interventional series leads to enhanced sensitivity associated with a modulation of response bias. Additionally, we have shown that repeated stimulations increase the impact of intervention. Conversely, a marginal decelerating effect was noted in relation to the process of reducing RT through training.

Click here to read full article: https://jalimedical.com/ -bulletin

07/18/2025

Synchronizing the transcranial magnetic pulse with electroencephalographic recordings effectively reduces inter-trial variability of the pulse artefact

Authors: Mitsuaki Takemi, Hartwig Roman Siebner

DOI: https://doi.org/10.1371/journal.pone.0185154

Synchronizing TMS and data acquisition markedly reduced trial-to-trial variability of the pulse artefact in recordings from the phantom or from the scalp. Reduced trial-to-trial variability was also observed at high sampling frequencies. The use of a soft sheet reduced the variability in recordings on the head phantom, but not in human participants. Effective reduction of the trial-to-trial variability renders it possible to create an artefact template for off-line filtering. Template-based subtraction of the artefact from the EEG signals is a prerequisite to effectively recover the immediate physiological response in the stimulated cortex and inter-connected areas.

To read full article, click: https://jalimedical.com/ -bulletin

07/03/2025

Open-source toolbox for EEG-based Stimulation Monitoring (EStiMo) of brain states during TMS burst delivery

Authors: Armita Faghani Jadidi, Adam Ryszczuk, Domenico Voso, Angela Mastropasqua, Leo Tomasevic, Hartwig Roman Siebner

DOI: https://doi.org/10.1016/j.brs.2024.12.001

Real-time EEG monitoring is needed during testing of novel rTMS protocols with new burst patterns or accelerated schedules involving multiple sessions per day, offering online visualization of EEG metrics that could signal immediate effect and also potential induced abnormalities.

To read full article, click: https://jalimedical.com/ -bulletin

06/26/2025

Brain encoding of saltatory velocity through a pulsed pneumotactile array in the lower face

Authors: Rebecca Custead, Hyuntaek Oh, Yingying Wang, Steven Barlow

Processing dynamic tactile inputs is a primary function of the somatosensory system. Spatial velocity encoding mechanisms by the nervous system are important for skilled movement production and may play a role in recovery of sensorimotor function following neurological insult. Little is known about tactile velocity encoding in mechanosensory trigeminal networks required for speech, suck, mastication, and facial gesture.

Click here to read full article: https://jalimedical.com/ -bulletin

06/12/2025

A set of electroencephalographic (EEG) data recorded during amplitude-modulated transcranial alternating current stimulation (AM-tACS) targeting 10-Hz steady-state visually evoked potentials (SSVEP)

Authors: David Haslacher, Khaled Nasr, Stephen E. Robinson, Christoph Braun,
Surjo R. Soekadar

DOI: https://doi.org/10.1016/j.dib.2021.107011

Transcranial alternating current stimulation (tACS) can affect perception, learning and cognition, but the underlying mechanisms are not well understood. A promising strategy to elucidate these mechanisms aims at applying tACS while electric or magnetic brain oscillations targeted by stimulation are recorded.

To read full article, click: https://jalimedical.com/ -bulletin

06/02/2025

🔬🧠 Big shoutout to the NonInvasive Brain Stimulation Clinical Workshop at Beth Israel Deaconess Medical Center (BIDMC) in Boston’s Berenson-Allen Center for NIBS! The Brain Ultimate TMS Therapy System is currently on display and generating excitement among clinicians and researchers. Cutting-edge technology, expert-led training, and hands-on learning driving the future of neuroscience!

05/28/2025

Noninvasive Deep Brain Stimulation via Temporally Interfering Electric Fields

Authors: Nir Grossman, David Bono, Nina Dedic, Suhasa B Kodandaramaiah, Andrii Rudenko, Ho-Jun Suk, Antonino M Cassara, Esra Neufeld, Niels Kuster, Li-Huei Tsai, Alvaro Pascual-Leone, Edward S Boyden

DOI: https://doi.org/10.1016/j.cell.2017.05.024

(excerpt)...Given the remarkable therapeutic benefits of DBS for patients with otherwise treatment-resistant movement and affective disorders (Kringelbach et al., 2007), the prospects for noninvasive DBS using electricity are potentially exciting. Other methods for noninvasive DBS have been proposed, e.g., using transcranial ultrasound (Legon et al., 2014) or using expression of heat-sensitive receptors and injection of thermomagnetic nanoparticles (Chen et al., 2015), but the unknown mechanism of action (Plaksin et al., 2014) and the need to genetically manipulate the brain, respectively, may limit their immediate use in humans.

To read full article, click: https://jalimedical.com/ -bulletin

05/06/2025

Electric field temporal interference stimulation of neurons in vitro

Authors: Annika Ahtiainen, Lilly Leydolph, Jarno M. A. Tanskanen, Alexander Hunold, Jens Haueisen, Jari A. K. Hyttinen

DOI: 10.1039/D4LC00224E

A promising new technique known as temporal interference stimulation (TIS) has been proposed to open up new possibilities in the treatment of neurological and psychiatric conditions. TIS is a non-invasive electrical stimulation (ES) method that promises targeting of neuronal structures at specific depths.

Traditional non-invasive brain stimulation methods, such as transcranial magnetic stimulation (TMS) and transcranial electrical current stimulation (tES), have lacked selectivity and effectiveness to therapeutically address target structures at the necessary depth. Hence, the primary option has been invasive deep brain stimulation (DBS), despite its associated risks. TIS, however, possesses considerable promise, as it can be steered to affect specific deep regions without modulating the superficial layers of the brain.

TIS has been demonstrated to have the ability to target deep brain structures and modulate brain functions in vivo. TIS has been reported to cause minimal side effects and high tolerability.

Click here to read more: https://jalimedical.com/ -bulletin

04/23/2025

Are you considering offering TMS Therapy at your practice but hesitant about the upfront investment?

Click here to start your journey with us: https://www.jalimedical.com/tms-leasing

04/16/2025

The Use of Magnetic Resonance Spectroscopy as a Tool for the Measurement of Bi-hemispheric Transcranial Electric Stimulation Effects on Primary Motor Cortex Metabolism

Authors: Sara Tremblay, Vincent Beaulé, Sébastien Proulx, Louis-Philippe Lafleur, Julien Doyon, Małgorzata Marjańska, Hugo Théoret

DOI: https://doi.org/10.3791/51631

The idea of applying electricity to the human brain to modulate its activity has been studied since ancient times. In fact, writings from as early as the 11th century have been found that describe the use of the torpedo electric fish in the treatment of epileptic seizures. Yet, it is not until recently that non-invasive brain stimulation has received widespread interest in the scientific community as it was shown to produce modulatory effects on cognitive function and motor response. While transcranial magnetic stimulation (TMS) has been extensively studied since the early 1980's, recent interest in transcranial direct current stimulation (tDCS) has increased as it is now considered a viable treatment option for a wide range of neuropathologies, such as stroke, alcohol addiction, and chronic pain. tDCS has many advantages over neurostimulation techniques like TMS, for example, since it is relatively inexpensive, painless, well tolerated by patients, and portable, thus making it possible to administer at bedside.

Read full article by clicking: https://jalimedical.com/ -bulletin

03/07/2025

How Brain Ultimate TMS Makes Advanced Mental Health Care Easier and More Affordable

Exploring advancements in mental health treatment technology, the Brain Ultimate TMS Therapy System stands out as a notable innovation in Transcranial Magnetic Stimulation (TMS). TMS is an FDA-cleared, non-invasive therapy primarily used to treat major depressive disorder, with ongoing research aimed at expanding its approval to other neurological conditions.

Key advantages of the Brain Ultimate TMS include:

Cost Accessibility: Delivering high-quality treatment without excessive costs, making advanced mental health care more accessible for clinics and patients alike.

Optimized Patient Comfort and Efficiency: The system's design minimizes downtime between treatment sessions and ensures patient comfort, improving overall treatment efficiency.

Integrated Patient Management: Built-in software simplifies patient monitoring and documentation, streamlining clinical operations and enhancing patient care.

Transparent Cost Structure: Unlike many systems, Brain Ultimate does not involve ongoing per-session fees, reducing operational expenses for healthcare providers.

Comprehensive Setup: The Brain Ultimate system includes all essential equipment and accessories, facilitating quick and seamless integration into clinical practice.

Dedicated Customer Support for Clinical and Research Settings: Supported by Jali Medical, renowned for its exceptional customer service and reliability, the system benefits from customized support catering both to neuroscience researchers and clinical professionals. Jali Medical provides extensive training resources and ongoing assistance, ensuring optimal outcomes for both research and patient care.

Ideal for New Clinicians: Clinicians new to TMS solutions will find Brain Ultimate particularly user-friendly due to its intuitive design, comprehensive training support, and simplified operational protocols, making it easy to adopt and implement effectively in their practice.

The Brain Ultimate TMS Therapy System, combined with Jali Medical's versatile and committed support, offers clinicians and researchers a powerful, reliable, and accessible treatment solution in mental health care.

To learn more about Brain Ultimate TMS Therapy System, click here: https://jalimedical.com/brainultimate-yingchi-tms-clinical

Address

111 Speen St., 200 WorkBar, Suite 213
Framingham, MA
01710

Telephone

+17813760008

Website

http://www.jalimedical.com/

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