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Aesthetic Surgery Journal

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Aesthetic Surgery Journal

Aesthetic Surgery Journal, an official publication of The Aesthetic Society. It is also the official journal of The Rhinoplasty Society.

Aesthetic Surgery Journal is a peer-reviewed international journal focusing on scientific developments and clinical techniques in aesthetic surgery. An official publication of the American Society for Aesthetic Plastic Surgery (ASAPS), ASJ is also the official English-language journal of many major international societies of plastic, aesthetic and reconstructive surgery representing South America, Central America, Europe, Asia, and the Middle East.

08/30/2025

Artificial intelligence technologies are rapidly transforming the field of plastic surgery, offering new opportunities for improving patient outcomes through enhanced diagnostic capabilities, personalized treatment planning, and outcome prediction. However, the integration of these technologies into clinical practice requires navigation of complex regulatory frameworks established by the US Food and Drug Administration.
This review outlines the current FDA regulatory pathways relevant to AI applications in plastic surgery.

Read now: https://doi.org/10.1093/asj/sjaf051

08/28/2025

Should preoperative testing be routine in outpatient aesthetic surgery?
A new study of over 2,500 patients in a Canadian ambulatory surgery center found that routine bloodwork and ECGs frequently revealed unexpected abnormalities—leading to changes in care for nearly 1 in 10 patients.

But what do these results really mean for patient safety? Should testing be standardized for all, or risk-stratified for some?

📊 Article: Ziolkowski et al share real-world data on preoperative workups in the outpatient setting.
🗨️ Commentary: Expert perspective explores whether these findings justify universal protocols—or more selective approaches.
🎧 Plus: Audio abstract available!

🔗 Read the full article: https://doi.org/10.1093/asj/sjaf054

🔗 Read the commentary: https://doi.org/10.1093/asj/sjaf105

08/27/2025

RelabotulinumtoxinA is a novel, complex-free, ready-to-use liquid formulation of BoNT-A, approved in some markets for the treatment of adults with moderate-to-severe glabellar lines and lateral canthal lines.

How do patients feel about this novel treatment?

Read now to find out!
https://doi.org/10.1093/asj/sjaf063

08/25/2025

What do private equity and exosomes have in common? They’re both reshaping the landscape of modern aesthetic medicine—one from the top down, and the other at the cellular level.

📈 In one study, researchers tracked a 4300% rise in PE acquisitions of U.S. plastic surgery practices since 2000, with a sharp focus on high-demand aesthetic specialties and cash-only models. While investors tout operational efficiency, concerns around access and quality remain.
Read here: https://doi.org/10.1093/asj/sjaf034

🧬 Meanwhile, in a separate study, researchers explored how adipose-derived stem cell exosomes (ADSCs-exo) modulate skin T-cell responses during wound healing. Findings suggest a regulatory effect on inflammatory cytokines and T-cell activation—highlighting their potential to control immune responses in post-procedure recovery.
Explore the science: https://doi.org/10.1093/asj/sjaf040

Together, these studies reflect two very different, yet equally critical, directions in plastic surgery research: macroeconomic forces shaping the business of care—and microscopic interventions redefining how we heal.

08/22/2025

Patients with large or ptotic breasts undergoing ni**le-sparing mastectomy (NSM) face reconstructive challenges, including higher risks of complications and suboptimal aesthetic outcomes. Preshaping procedures, such as mastopexy or reduction mammoplasty, have been proposed to optimize surgical outcomes by improving breast dimensions before NSM. This systematic review evaluates the safety and efficacy of these approaches.

Read now: https://doi.org/10.1093/asj/sjaf058

08/21/2025

This study investigates the change in symptoms, quality of life, and patient satisfaction in patients who underwent abdominoplasty with diastasis correction

Read now: https://doi.org/10.1093/asj/sjaf057

08/20/2025

Stem cell enrichment without enzymes? This device platform makes it possible.
Mechanical processing of lipoaspirate is evolving—and this latest study explores how shear forces can refine regenerative output without enzymatic digestion.

Here’s what the team found when using their new 3-device platform (including a novel shearing device):
🧬 Significant enrichment of endothelial progenitor cells
🧪 Enhanced angiogenesis in vitro
🧠 Stronger activation of wound-healing genes after culture
📉 No loss in mesenchymal stem cell viability

Compared to standard nanofat prep, the results show real promise for improving cell-based therapies—with scalable tech already in the pipeline.

🔗 Full paper: https://doi.org/10.1093/asj/sjaf055

08/19/2025

Many board-certified plastic surgeons believe that accessibility of hands-on training in ultrasound-guided gluteal fat grafting (US-GGFG) is insufficient. Cadaver models utilized to practice ultrasound-guided fat grafting have proven to be expensive and difficult to procure.

The authors of this study present a novel, clinically relevant buttock model, and compare this model with the costs and logistics of the cadaver model with the aim of providing affordable hands-on training for US-GGFG.

Read here: https://doi.org/10.1093/asj/sjaf065

08/18/2025

What if the future of HA fillers didn’t rely on heat? 🔬
A new generation of cold-crosslinked HA fillers—Evolysse Form and Evolysse Smooth—was recently evaluated in a split-face trial comparing them to a widely used traditional filler, Restylane-L.

Here’s what stood out from this rigorous 140-patient study:
📈 Both cold-crosslinked fillers achieved statistically superior wrinkle improvement at key time points
📆 Results held for up to 12 months
🤝 Blinded raters, treating physicians, and patients all aligned on outcome quality
💡 FACE-Q scores confirmed aesthetic improvement

Why this matters: For practices looking to diversify their HA offerings, these data suggest that cold-crosslinking may offer enhanced performance—without sacrificing tolerability.

🔗 Full study: https://doi.org/10.1093/asj/sjaf080

08/15/2025

What if improving submental fullness could go beyond fat reduction—and enhance both skin and muscle tone?

This prospective study evaluated a novel combination of high-intensity focused electrical stimulation (HIFES) and Synchronized Radiofrequency+ (Sync RF+) in the submental and cheek region.

🔬 MRI and 3D imaging showed measurable volume reductions at both 1- and 3-month follow-ups.
📉 Submental fat decreased by more than 30% at 3 months.
💬 Nearly 94% of patients were satisfied with their results.

But the true value? This dual-modality approach may offer more than just fat reduction—suggesting improvements in tissue quality, muscle tone, and aesthetic contour.

✔️ New evidence for noninvasive lower-face sculpting
✔️ High patient tolerability and satisfaction
✔️ Objective volume reductions confirmed by MRI & 3D imaging

💡 Curious what sets this technology apart from other noninvasive treatments?
🔗 Read the full study: https://doi.org/10.1093/asj/sjaf048

08/14/2025

Higher grades of gynecomastia with marked skin excess, an enlarged ni**le-areola complex (NAC), and a feminine chest shape pose certain unique challenges. To achieve outcomes similar to the those for lower grades, management of excess skin and an enlarged NAC is critical. Surgical removal of excess skin produces visible scars, and repositioning of the NAC with a free ni**le graft leads to loss of sensation.

The aim of the study was to compare the skin tightening or “chest lift” and reduction in the NAC area achieved with a combination treatment of radiofrequency (RF) energy and power-assisted liposuction (PAL) to those treated with PAL alone in higher grades of gynecomastia.

Read now: https://doi.org/10.1093/asj/sjaf074

08/13/2025

Post-op bruising and swelling: What actually works?

In rhinoplasty recovery, we’ve long used dexamethasone to minimize edema and ecchymosis—but what if a topical agent could do the same, minus the systemic effects?

This triple-blind RCT compared:
🔹 Systemic dexamethasone
🔹 Topical tranexamic acid (TXA)
🔹 Their combination
🔹 Control

Here’s what stood out:
📉 TXA and dexamethasone both worked—about equally well
🚫 Combining them didn’t move the needle
💡 Topical TXA offers a steroid-free option for patients with contraindications

For surgeons managing high-demand patients, these results offer practical guidance for customizing post-op care—and perhaps avoiding unnecessary polypharmacy.

🔗 Full study: https://doi.org/10.1093/asj/sjaf073

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