09/02/2025                                                                            
                                    
                                                                            
                                            Near-infrared (NIR) light at wavelengths like 808 nm and 905 nm can enhance the proliferation and differentiation of stem cells, promoting their ability to repair tissues. This process, known as photobiomodulation, utilizes specific light wavelengths to stimulate cellular functions and improve stem cell activity.
 deeplyvitalmedical.com BioMed Central
Effects of Near-Infrared Light on Stem Cells
Overview of Near-Infrared Light
Near-infrared (NIR) light, particularly at wavelengths like 808 nm and 905 nm, is used in photobiomodulation (PBM) therapy. This therapy stimulates cellular processes, enhancing stem cell proliferation and differentiation.
Impact on Stem Cell Proliferation
Increased Proliferation: NIR light exposure has been shown to significantly boost the replication rate of stem cells. For instance, studies indicate that NIR light can enhance the proliferation of adipose-derived stem cells, making them multiply faster.
Mechanism: The light interacts with mitochondrial components, particularly cytochrome c oxidase, leading to increased ATP production. This energy boost supports cell growth and survival.
Influence on Differentiation
Enhanced Differentiation: NIR light not only promotes proliferation but also aids in the differentiation of stem cells into various cell types. This is crucial for tissue repair and regeneration.
Specific Wavelengths: Research suggests that different wavelengths may have varying effects. For example, 808 nm is often used for its effectiveness in stimulating cellular responses, while 905 nm may also contribute positively to stem cell behavior.
Summary of Benefits
Wavelength Effect on Stem Cells Mechanism
808 nm Increased proliferation Enhanced ATP production
905 nm Promotes differentiation Stimulates cellular processes
NIR light therapy shows promise as a non-invasive method to enhance stem cell activity, potentially benefiting regenerative medicine and therapies for various conditions.