Grand River Aseptic Manufacturing

05/07/2026

Discover our newest syringe and cartridge filling capability for the growing biologics market—built to deliver precise control of critical drug‑device parameters at medium to high volumes.

Featuring the Groninger USA UFVN syringe filler with SKAN isolator technology for advanced sterility assurance and consistent ISO-compliant performance.

https://hubs.la/Q04dWXxc0

05/01/2026

CEO Denis Johnson recently spoke with Crain's Grand Rapids Business about GRAM’s continued expansion in both facilities and talent. https://hubs.la/Q04f257d0

Investment will expanding the company's capacity to fill syringes and cartridges for pharmaceutical clients.

04/17/2026

Stay current on Grand River Aseptic Manufacturing's U.S.-based sterile filling capacity in this webinar 🎤💉

https://hubs.la/Q04bXLnj0

04/14/2026

Today, we announce a significant investment to expand GRAM's sterile injectable drug product manufacturing capacity and capabilities for high-volume commercial products.

GRAM has invested $100 million in its fifth sterile-filling line and fifth Good Manufacturing Practice (GMP) facility.

The new sterile filling line, a Groninger USA 10-head fill line equipped with a SKAN isolator, is designed to manufacture high-volume prefilled syringes and cartridges while ensuring compliance with evolving Annex 1 standards. The line will accommodate a variety of syringe sizes ranging from 1mL to 10mL, and cartridge sizes from 1.5mL to 20mL.

🎉Congratulations to both teams on the successful FAT for our groninger 10-head syringe and cartridge filling line!

Read the latest press release and watch a video from the FAT: https://hubs.la/Q04bXJmV0

03/31/2026

Tune in to the Outsourced Pharma Fill-Finish Capabilities Update in April to hear from Kevin Wess as he walks through the latest on GRAM’s sterile fill-finish capacity and how it can support your pipeline.

Stay current on U.S.-based CDMO capacity and inform your outsourcing strategy.
https://hubs.la/Q047-0wC0

03/31/2026

At Grand River Aseptic Manufacturing, we do not view Annex 1 as the end goal—it is our starting point. We use it as our foundation for building a modern sterility assurance program that anticipates how regulatory expectations will continue to evolve.

In our latest article, our Director of QA & Regulatory Affairs shares how GRAM moves beyond basic Annex 1 compliance to build more resilient, future-ready aseptic operations.

https://hubs.la/Q0496FrK0

03/17/2026

Where is sterile fill-finish headed next?

GRAM CEO Denis Johnson outlines how the CDMO landscape is likely to evolve over the next three years—and how Grand River Aseptic Manufacturing is preparing for its next phase of sterile filling growth. From a more segmented, highly specialized CDMO market to the critical need for consistency amid rapid expansion, he shares what pharma leaders should know to stay ahead of what’s coming.
➡️ https://hubs.la/Q0477VcP0

03/16/2026

Be on the lookout for Dave Powell and Mico Holguin at the International Society for Pharmaceutical Engineering San Francisco Chapter's 33rd Annual Vendor Night!

Date: March 19, 2026 | 4-8 PM
Location: Oracle Park | San Francisco, CA

See you there!

02/26/2026

In this episode of The Top Line, Denis Johnson, CEO of Grand River Aseptic Manufacturing (GRAM), shares his insights on the growing demand and evolving specialization expected in the next three years. He highlights how increased regulatory oversight and a focus on U.S.-based manufacturing make expertise, rather than just equipment, a crucial factor for success in our industry.

For leaders navigating supply and growth, this conversation offers a clear view of where sterile manufacturing is headed — and how to prepare.

Listen to the podcast -
https://hubs.la/Q044d4hf0

02/11/2026

DCAT Week is quickly approaching! Denis Johnson, Dave Powell, Kevin Wess, Brent Todd, and Mico Holguin will be on-site to discuss how GRAM’s advanced aseptic manufacturing and filling platforms bring the flexibility you need from clinical to commercial. Are you exploring new syringe, cartridge, or vial formats and need a more agile CDMO partner?

Schedule a meeting now to connect in New York: https://hubs.la/Q041MBwh0

02/03/2026

Engaging with a CDMO can significantly enhance your pharmaceutical manufacturing endeavors. By choosing a partner that prioritizes safety, quality, and innovation, companies can navigate the industry’s complexities with greater confidence. The journey towards manufacturing excellence is continuous, and with the right collaboration, the possibilities are endless.
https://hubs.la/Q041nPKV0

Change is constant in pharma, and companies must keep pace with regulatory requirements, technological advancements, and patient expectations.

01/29/2026

Looking to make a difference this summer?

At Grand River Aseptic Manufacturing (GRAM), our work helps bring sterile injectable therapies one step closer to the patients who need them most—and our interns are part of that mission.

If you’re a sophomore or above, this is an opportunity to build meaningful experience while making a tangible impact. Learn more about our at
https://hubs.la/Q040YJVW0