12/23/2025
Between wrapping gifts and decking the halls, don’t forget the one person who deserves a little lift — you. 👀💧If you have low-lying lids, talk to your healthcare provider or visit upneeq.com to see if the eyedrop that lifts might be right for you this holiday season.
IMPORTANT SAFETY INFORMATION
UPNEEQ® (oxymetazoline hydrochloride ophthalmic solution), 0.1% is a prescription eyedrop used to treat acquired blepharoptosis (low-lying eyelids) in adults.
Warnings and precautions
Low-lying eyelids may be related to conditions such as stroke and/or brain aneurysm, Horner syndrome, myasthenia gravis, loss of the ability to move eye muscles, eye infection and eye tumors. Your doctor should evaluate you for these conditions.
Ask your doctor if you have any of the following conditions or if any of the following symptoms, which UPNEEQ may increase, get worse:
-Heart disease, uncontrolled high or low blood pressure, or if you feel faint at rest or when quickly standing up;
-Reduced blood flow to the brain or heart, or eye or mouth dryness due to an immune system disorder (Sjögren’s syndrome);
Increase in eye pressure due to fluid buildup due to untreated narrow-angle glaucoma.
Do not let the tip of the UPNEEQ vial touch your eye or any other surface. This can help prevent eye injury or contamination. Each UPNEEQ vial is for one-time use. Discard after use.
Common side effects
The most common side effects with UPNEEQ (1-5% of patients) were eye inflammation, eye redness, dry eye, blurred vision, eye pain at time of use, eye irritation, and headache.
Tell your doctor
-Your full medical history.
-If you currently take an alpha-adrenergic antagonist medication to treat heart disease or an enlarged prostate, beta-blockers, or other medications to treat hypertension or an abnormal heartbeat.
-If you use a certain class of antidepressant medication (monoamine oxidase inhibitors), as it may affect the way your body absorbs the medication.
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Upneeq® is a registered trademark of RVL Pharmaceuticals, Inc.
