05/03/2025
๐ฃ๐ฑ๐ฎ ๐ฟ๐ฒ๐ฝ๐ช๐ต ๐ฌ๐ธ๐ท๐ท๐ฎ๐ฌ๐ฝ๐ฒ๐ธ๐ท ๐ซ๐ฎ๐ฝ๐๐ฎ๐ฎ๐ท ๐12 &. ๐๐พ๐ฝ ๐ฑ๐ฎ๐ช๐ต๐ฝ๐ฑ ๐ช๐ท๐ญ ๐ฝ๐ฑ๐ฎ ๐๐ฎ๐ป๐ฟ๐ธ๐พ๐ผ ๐ข๐๐ฝ๐ผ๐ฝ๐ฎ๐ถ
Vitamin B12 is a powerhouse nutrient essential for both optimal digestion and a healthy nervous system. Unlike most vitamins, B12 requires a complex absorption process that begins in the gut, making digestive function critical for its bioavailability.
B12 absorption depends on:
Stomach acid (to release B12 from food)
Intrinsic factor (a protein made by stomach cells)
A healthy small intestine (for uptake)
Conditions like low stomach acid (hypochlorhydria), leaky gut, H. pylori infections, or autoimmune gastritis (pernicious anemia) can severely impair B12 absorption, leading to deficiency.
Even with a B12-rich diet, poor gut function can trigger deficiency symptoms like fatigue, brain fog, and nerve damage.
The Gut-Brain-Nerve Axis
B12 is crucial for:
Myelin sheath formation (protects nerves, prevents neuropathy)
Neurotransmitter production (serotonin, dopamineโ90% made in the gut!)
Methylation (detox, energy, mood regulation)
A deficiency can contribute to depression, cognitive decline, and peripheral neuropathy highlighting why gut health directly impacts neurological resilience.
- If you have gut issues (IBS, SIBO, acid reflux), test B12 levels!
- Sublingual or injectable B12 may be needed if absorption is impaired.
- Support gut health (probiotics, betaine HCl if low acid) to optimize B12 status
Supporting Studies:
1. B12 Deficiency & Gastrointestinal Disorders
[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993789/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993789/)
2. B12โs Role in Neurological Function
[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262614/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262614/)
Struggling with fatigue, brain fog, or gut issues? Letโs check your B12 status!