Mark Vitale, MD, MPH

08/27/2025

I’m excited to be participating in the DocMatter platform to help colleagues treat patients with Dupuytren's disease. Read more at the link to follow: https://tinyurl.com/3jpnz7wh

I’m excited to be participating in the DocMatter platform to help colleagues treat patients with Dupuytren's disease. See this post for more information: https://lnkd.in/eMmjhiJm

05/24/2025

I was honored to be a speaker at the International Conference on Dupuytren Disease in Brussels, May 16-17 where I discussed the role of collagenase and the problem of contracture recurrence. I learned about new findings on genetics, cellular biology and evolving treatments from speakers from Europe, Australia and the US. These presenters spoke about the role for humira in early disease, radiation therapy and innovative surgical techniques. Thanks to Dr. DeGreef for hosting a great meeting!

03/08/2025

I am excited to have performed the first ten endoscopic carpal tunnel releases with the newly released VECTR device by Rafael Medical Devices. The VECTR is an all-in-one peel pack system that allows a surgeon to efficiently and safely perform endoscopic carpal tunnel release in a very small footprint without bulky arthroscopy equipment or need to sterilize equipment. This will allow surgeons to reduce turnover times and sterilization costs at ASCs and even enhance the ability to perform this surgery under WALANT local analgesia in the office setting.

12/19/2024

Wishing you and your families Happy Holidays as we celebrate the end of 2024 and ring in the New Year.

10/31/2024

Proud to support Project Music. Last week, I attended Project Music's Tenth Anniversary Gala Extravaganza with my partner and fellow hand surgeon Dr. Matthew Cantlon. All proceeds from the event supported Project Music and their mission to use the transformative power of music to effect positive social change for the students most in need of access, opportunity, and inspiration.

https://www.facebook.com/ProjectMusicCT
Orthopaedic and Neurosurgery Specialists

09/28/2024

I learned a lot about Dupuytren's contracture from our panel of thought leaders from around the world as I moderated an Instructional Course Lecture at the 2024 ASSH in Minneapolis—International Perspectives on Dupuytren's Disease. Thank you to our speakers, Drs. Prosper Benhaim (USA), Juan Carlos Marquez (Spain), Donald Lalonde (Canada), Ilse Degreef (Belgium), and Paul Werker (Netherlands).

American Society for Surgery of the Hand

08/10/2024

Proud of my coauthors at the ONS Foundation and honored to coauthor this study with one of my mentors who developed this technique, Dr. Bernard Morrey, from the Mayo Clinic. Intrabursal injection of doxycyline was a safe and effective alternative to surgical treatment for olecranon bursitis refractory to conservative management.

Orthopaedic and Neurosurgery Specialists

06/21/2024

On Saturday, Greenwich Hospital welcomed Dr. Charlie Eaton, one of the world’s experts on Dupuytren’s Disease of the hand and the surgeon who brought needle fasciotomy to the US. He presented a seminar on the challenges of treating this condition and his work with the Dupuytren Research Group to accelerate the quest for a cure. Thank you, Dr. Eaton, for sharing your wisdom.

05/25/2024

I am such a proud daddy of my daughter, Sienna, who did a beautiful job at her ballet recital this week.

04/06/2024

Spent a day teaching my son about bones at the dinosaur exhibit at the Museum of Natural History. Maybe Luca is a budding orthopedic surgeon?

12/29/2023

Happy holidays from the Vitale family as 2023 comes to a close and we prepare to ring in 2024.

10/14/2023

Fascinating study out of UK and Netherlands examining anti-TNF therapy as a target to treat early stage Dupuytren's disease of the hand. TNF is thought to activate the contractility of myofibroblasts, and this trial found that anti-TNF (adalimumab) injected into nodules reduced nodule size and hardness at 18 months. Currently surgery, collagenase and percutaneous needle aponeurotomy are the only options to treat later stage Dupuytren's once contractures have already developed, but the ideal "cure" would be a way to prevent nodules from progressing to contractile cords. https://pubmed.ncbi.nlm.nih.gov/35949922/

Intranodular injections of adalimumab in participants with early-stage Dupuytren's disease resulted in softening and reduction in size of the nodules. Longer follow-up would be required to assess the effect of tumour necrosis factor inhibition on disease progression, extension deficit and hand funct...