MGD MGD is a CLIA certified lab based in NJ specialized in genetic testing.

Lifestyle plays a major role, sometimes even more than genetics. Obesity is the strongest lifestyle-related cause of end...
12/06/2025

Lifestyle plays a major role, sometimes even more than genetics. Obesity is the strongest lifestyle-related cause of endometrial cancer—about 40% of cases are linked to excess body fat. This is because fat tissue converts hormones into estrogen, creating a constant high-estrogen environment. Insulin resistance, prediabetes, and metabolic syndrome also increase risk by raising insulin and growth-factor levels that stimulate cell growth in the uterus. A diet high in sugar, refined carbs, and processed foods can worsen these changes. Smoking, long-term physical inactivity, and chronic inflammation add to the risk as well. Improving diet quality, losing even a small amount of weight, and staying active can significantly reduce the chances of developing endometrial cancer.

A smaller but important percentage of endometrial cancer cases come from genetic mutations, especially Lynch syndrome, w...
12/04/2025

A smaller but important percentage of endometrial cancer cases come from genetic mutations, especially Lynch syndrome, which affects DNA repair and dramatically increases the risk of uterine and colon cancers. Women with a family history of endometrial, colon, or ovarian cancer may also be at higher risk. Certain medical issues contribute as well: diabetes, chronic high blood pressure, thyroid problems, and polycystic o***y syndrome can all raise risk due to metabolic and hormonal changes. Tamoxifen, a medication used for breast cancer, slightly increases the chance of endometrial cancer because it acts like estrogen in the uterus. Even having previous radiation to the pelvis can elevate the long-term risk.

Endometrial cancer is strongly tied to long-term exposure to unopposed estrogen—meaning estrogen levels stay high withou...
12/01/2025

Endometrial cancer is strongly tied to long-term exposure to unopposed estrogen—meaning estrogen levels stay high without enough progesterone to balance them. This imbalance causes the uterine lining to keep thickening, which can eventually lead to abnormal or cancerous cells. This happens more often in women with PCOS, irregular or absent periods, early first period, late menopause, or those who take estrogen-only hormone replacement after menopause. Conditions like estrogen-producing ovarian tumors also increase risk. Even factors like not having children, because pregnancy gives long breaks from estrogen exposure, can raise the chances. Hormonal balance is a major piece of the puzzle in understanding how this cancer develops.

Several lifestyle and environmental factors can influence leukemia risk over time. Smoking introduces benzene and other ...
11/27/2025

Several lifestyle and environmental factors can influence leukemia risk over time. Smoking introduces benzene and other toxins directly into the bloodstream, significantly raising the risk of certain leukemia types. People with weakened immune systems, such as those taking long-term immune-suppressing drugs after organ transplants, are also more vulnerable. Long-term exposure to industrial chemicals, pesticides, or solvents can contribute as well. Reducing harmful exposures, avoiding smoking, and maintaining regular medical follow-ups can make a real difference in lowering overall risk.

While leukemia isn’t usually considered a hereditary disease, some genetic conditions can increase risk. People with Dow...
11/24/2025

While leukemia isn’t usually considered a hereditary disease, some genetic conditions can increase risk. People with Down syndrome, Li-Fraumeni syndrome, Fanconi anemia, or other inherited bone-marrow or immune disorders have cells that are more prone to DNA changes. These conditions don’t guarantee leukemia will happen, but they raise the likelihood. Families with a strong history of blood cancers may also need more regular checkups. Understanding these genetic links helps with early detection and better long-term monitoring.

Leukemia often starts when DNA in bone-marrow cells becomes damaged, leading to abnormal blood cell growth. One major tr...
11/22/2025

Leukemia often starts when DNA in bone-marrow cells becomes damaged, leading to abnormal blood cell growth. One major trigger is exposure to high levels of radiation, such as previous radiotherapy for another cancer or accidental radiation exposure. Certain chemotherapy drugs used in the past can also slightly increase the risk of developing leukemia years later. Another important factor is benzene, a chemical found in gasoline fumes, industrial factories, and even cigarette smoke. Long-term contact with these triggers can raise the chances of leukemia, which is why protective safety measures and avoiding smoke exposure are so important.

Chronic inflammation in the colon is another major cause of colon cancer. People with long-term bowel diseases like ulce...
11/20/2025

Chronic inflammation in the colon is another major cause of colon cancer. People with long-term bowel diseases like ulcerative colitis or Crohn’s disease are more likely to develop abnormal cell growth. Over many years, inflammation damages the lining of the colon, leading to mutations that can progress to cancer. Type 2 diabetes and insulin resistance are also linked to higher colon cancer risk. Managing these conditions through medication, diet, and lifestyle changes — along with regular colonoscopies — helps protect colon health and prevent cancer.

Having a family history of colon cancer significantly raises your personal risk, especially if a close relative was diag...
11/17/2025

Having a family history of colon cancer significantly raises your personal risk, especially if a close relative was diagnosed before age 50. Some people inherit genetic syndromes like Lynch syndrome (HNPCC) or familial adenomatous polyposis (FAP), which cause abnormal growths (polyps) in the colon that can turn cancerous over time. If colon cancer runs in your family, genetic counseling and early screening — sometimes starting as young as 20–25 — are vital. Detecting and removing precancerous polyps early can prevent the disease altogether.

What you eat and how you live play a major role in colon cancer risk. Diets high in red and processed meats — like sausa...
11/15/2025

What you eat and how you live play a major role in colon cancer risk. Diets high in red and processed meats — like sausages, bacon, and deli meats — are linked to DNA damage in colon cells. At the same time, low intake of fiber, fruits, and vegetables slows digestion and increases contact time between toxins and the intestinal lining. Obesity, lack of exercise, and excessive alcohol consumption also raise risk by increasing inflammation and hormone imbalances in the body. On the other hand, regular physical activity, a diet rich in fiber, and maintaining a healthy weight can dramatically reduce your risk of developing colon cancer.

About 10% of pancreatic cancer cases are linked to genetics. Inherited mutations — such as BRCA1, BRCA2, PALB2, or Lynch...
11/13/2025

About 10% of pancreatic cancer cases are linked to genetics. Inherited mutations — such as BRCA1, BRCA2, PALB2, or Lynch syndrome — can impair DNA repair and lead to abnormal cell growth in the pancreas. Having multiple close family members with pancreatic cancer increases personal risk significantly. Individuals with hereditary risk factors should consider genetic counseling and regular medical follow-up. Knowing your family history allows earlier detection and empowers proactive prevention.

Long-term inflammation of the pancreas — known as chronic pancreatitis — increases the risk of pancreatic cancer. It can...
11/10/2025

Long-term inflammation of the pancreas — known as chronic pancreatitis — increases the risk of pancreatic cancer. It can develop due to repeated pancreatitis attacks, gallstones, heavy alcohol use, smoking, or genetic disorders. People with type 2 diabetes or obesity are also at higher risk, as these conditions cause insulin-related metabolic changes that stress pancreatic cells. Managing chronic pancreatitis, controlling blood sugar, maintaining healthy weight, and limiting alcohol intake help protect the pancreas and reduce long-term cancer risk.

Smoking is one of the strongest known risk factors for pancreatic cancer. Chemicals from ci******es enter the bloodstrea...
11/08/2025

Smoking is one of the strongest known risk factors for pancreatic cancer. Chemicals from ci******es enter the bloodstream and reach the pancreas, causing DNA damage and inflammation that can lead to cancer over time. Smokers are 2–3 times more likely to develop pancreatic cancer than non-smokers, and even exposure to second-hand smoke increases risk. The good news? Risk starts to drop soon after quitting and continues to decrease over the years. Protecting your lungs also protects your pancreas — quitting smoking is one of the most powerful prevention steps you can take.

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Haddonfield, NJ
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