10/23/2025
Some people inherit genetic abnormalities that make them more prone to leukemia. Conditions like Down syndrome, Fanconi anemia, and Bloom syndrome are associated with a higher risk. Additionally, patients who have undergone chemotherapy or radiation therapy for other cancers can develop secondary leukemia years later due to DNA damage from treatment. Family history also plays a role — having a close relative with leukemia slightly increases the risk. Regular health checkups and blood tests are recommended for those with known genetic predispositions or previous cancer treatment.