MGD MGD is a CLIA certified lab based in NJ specialized in genetic testing.

Some people inherit genetic abnormalities that make them more prone to leukemia. Conditions like Down syndrome, Fanconi ...
10/23/2025

Some people inherit genetic abnormalities that make them more prone to leukemia. Conditions like Down syndrome, Fanconi anemia, and Bloom syndrome are associated with a higher risk. Additionally, patients who have undergone chemotherapy or radiation therapy for other cancers can develop secondary leukemia years later due to DNA damage from treatment. Family history also plays a role — having a close relative with leukemia slightly increases the risk. Regular health checkups and blood tests are recommended for those with known genetic predispositions or previous cancer treatment.

Certain toxic chemicals, especially benzene, play a strong role in leukemia development. Benzene, found in cigarette smo...
10/20/2025

Certain toxic chemicals, especially benzene, play a strong role in leukemia development. Benzene, found in cigarette smoke, industrial emissions, and some solvents, harms bone marrow and interferes with normal blood cell formation. Workers in industries like rubber manufacturing, oil refineries, and chemical plants may face higher exposure risks. Prolonged inhalation or contact allows benzene to enter the bloodstream, damaging the cells that produce healthy white and red blood cells. Avoiding cigarette smoke, ensuring proper workplace ventilation, and using protective equipment are vital preventive measures.

Exposure to high levels of ionizing radiation is a major known cause of leukemia. This type of radiation can pe*****te d...
10/18/2025

Exposure to high levels of ionizing radiation is a major known cause of leukemia. This type of radiation can pe*****te deep into the body and damage the DNA of bone marrow cells, where blood is produced. When this DNA damage isn’t properly repaired, abnormal white blood cells start multiplying uncontrollably, leading to leukemia. People previously treated with radiation therapy for other cancers or exposed to nuclear accidents are at higher risk. Even though daily background radiation (like from X-rays or the environment) is minimal, unnecessary or repeated exposure should still be avoided whenever possible.

Melanoma risk is much higher in people with fair skin, light eyes, or blond/red hair because they have less melanin, the...
10/16/2025

Melanoma risk is much higher in people with fair skin, light eyes, or blond/red hair because they have less melanin, the pigment that naturally protects against UV damage. Having many moles, especially atypical or irregular ones, also raises the risk since they are more likely to turn cancerous. Weakened immune systems (from conditions like HIV or after organ transplantation) further reduce the body’s ability to detect and destroy abnormal cells. Regular skin checks, both self-exams and professional exams, are vital for early detection, when melanoma is highly treatable.

Around 1 in 10 people with melanoma have a close relative who also developed it. Inherited mutations, such as in the CDK...
10/13/2025

Around 1 in 10 people with melanoma have a close relative who also developed it. Inherited mutations, such as in the CDKN2A or BRAF genes, disrupt the body’s ability to control cell growth or repair DNA, making melanoma more likely. People with a strong family history should be extra cautious about UV exposure and monitor their skin regularly. Genetic counseling and early dermatology screenings can help identify changes before they turn into invasive cancer.

Ultraviolet (UV) radiation from the sun and tanning beds is the leading cause of melanoma. UV rays pe*****te the skin an...
10/11/2025

Ultraviolet (UV) radiation from the sun and tanning beds is the leading cause of melanoma. UV rays pe*****te the skin and damage DNA in pigment-producing cells (melanocytes). When these cells accumulate mutations, they can begin growing uncontrollably, forming melanoma. Sunburns — especially blistering ones during childhood — double the lifetime risk. Indoor tanning is equally dangerous, with studies showing it significantly increases melanoma rates in young people. Protecting skin with sunscreen, hats, clothing, and avoiding midday sun is one of the most effective ways to prevent melanoma.

Smoking increases the risk of gastric cancer by exposing the stomach lining to carcinogens found in to***co smoke. These...
10/09/2025

Smoking increases the risk of gastric cancer by exposing the stomach lining to carcinogens found in to***co smoke. These chemicals are ingested and accumulate in the stomach, causing DNA damage that can lead to cancerous mutations. Smokers face almost double the risk of developing stomach cancer compared to non-smokers, and the risk is especially high for tumors in the upper stomach near the esophagus. The longer and heavier the smoking habit, the greater the danger. The good news: quitting smoking reduces the risk steadily, and after about 10–15 years, the risk drops significantly compared to current smokers.

Diet is a powerful factor in gastric cancer risk. Foods that are heavily salted, smoked, or pickled — such as processed ...
10/06/2025

Diet is a powerful factor in gastric cancer risk. Foods that are heavily salted, smoked, or pickled — such as processed meats, cured fish, and preserved vegetables — damage the protective lining of the stomach. Salt itself weakens the stomach’s defense, while processed foods often contain nitrates and nitrites that can form nitrosamines, potent carcinogens directly linked to stomach cancer. Regions with diets high in these foods, such as parts of East Asia and Eastern Europe, report much higher gastric cancer rates. On the other hand, fresh fruits and vegetables, rich in antioxidants and vitamin C, help protect the stomach lining and reduce cancer risk.

Chronic infection with Helicobacter pylori (H. pylori) is the leading cause of gastric cancer worldwide. This bacteria l...
10/04/2025

Chronic infection with Helicobacter pylori (H. pylori) is the leading cause of gastric cancer worldwide. This bacteria lives in the stomach lining and, if left untreated, can cause chronic gastritis, ulcers, and progressive changes in stomach cells. Over years, these changes may evolve into precancerous lesions and eventually cancer. Not everyone with H. pylori develops cancer — genetics, diet, and lifestyle also play a role — but those with long-term infection face a much higher risk. Simple tests can detect H. pylori, and antibiotics combined with acid-reducing drugs can eliminate it, dramatically lowering the chance of stomach cancer if treated early.

Chronic lung diseases such as chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, and even old tuberculosi...
10/02/2025

Chronic lung diseases such as chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, and even old tuberculosis infections increase lung cancer risk. These conditions cause scarring, inflammation, and structural changes in lung tissue, which create an environment where abnormal cells can grow unchecked. Studies show that patients with COPD have up to a fourfold higher risk of developing lung cancer compared to those without. Managing these conditions with medication, pulmonary rehab, and regular monitoring doesn’t just improve quality of life — it can also help reduce the risk of lung cancer.

Lung cancer isn’t always tied to smoking. People with close relatives who had lung cancer face a higher risk, suggesting...
09/29/2025

Lung cancer isn’t always tied to smoking. People with close relatives who had lung cancer face a higher risk, suggesting that inherited genetic factors play a role. Some families carry mutations that impair how lung cells repair DNA or handle toxins, making them more susceptible to cancerous changes. Even non-smokers with a family history may benefit from regular health check-ups, imaging if recommended, and lifestyle adjustments like avoiding smoke and pollutants. Knowing your family history and discussing it with a doctor is an important step in prevention.

Smoking is the direct cause of most lung cancer cases. The carcinogens in to***co smoke damage the DNA of lung cells, le...
09/27/2025

Smoking is the direct cause of most lung cancer cases. The carcinogens in to***co smoke damage the DNA of lung cells, leading to mutations in critical genes like KRAS and TP53 that drive lung cancer growth. Each cigarette increases the cumulative damage, making lung cancer more likely over time. Heavy smokers face up to 30 times higher risk compared to non-smokers. Even people exposed to secondhand smoke have a measurable increase in lung cancer risk. The good news is that quitting slows down this damage — within a few years, the risk of developing lung cancer starts to decline, though it never returns fully to that of a non-smoker. Smoking remains the single most important factor in preventing lung cancer deaths worldwide.

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