11/20/2025
Long educational post alert 🔊🔊
✨ Why We Compound Tirzepatide With Glycine (Not B Vitamins) ✨
At IYKYK Aesthetics, we’re intentional about every ingredient we choose — especially when it comes to your weight-loss medications. One of the most common questions we get is:
“Why is my tirzepatide compounded with glycine instead of B vitamins?”
Here’s the simple answer:
➡️ Rapid weight loss can put you at risk for muscle loss… and glycine helps protect your lean muscle.
Let’s break down how it works 👇
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💪 Glycine’s Role in Protecting Muscle During Weight Loss
When your body loses weight quickly, it doesn’t just burn fat — it may break down muscle tissue for energy. This is something we want to prevent, because muscle is crucial for:
• A healthy metabolism
• Maintaining your strength and energy
• Long-term weight management
• Overall body composition and tone
Glycine is a foundational amino acid that helps keep your muscle tissue strong while you're losing fat.
Here’s how:
🔹 1. Supports Collagen & Connective Tissue
Glycine is one of the three main amino acids that build collagen — which is essential for healthy muscles, joints, and connective tissue. Stronger connective tissue means your muscles stay supported during rapid fat loss.
🔹 2. Helps Reduce Muscle Breakdown (Anti-Catabolic)
Glycine has been shown to reduce the breakdown of muscle proteins by calming inflammatory pathways and supporting better recovery. This means your body is less likely to use muscle as fuel.
🔹 3. Improves Glucose Management & Insulin Sensitivity
Better blood-sugar control allows your body to burn fat more efficiently instead of dipping into muscle stores for energy. Glycine naturally supports these pathways — and when combined with tirzepatide, the benefits stack beautifully.
🔹 4. Supports Better Sleep (Which = Better Muscle Retention)
Glycine helps promote deeper, restorative sleep. And since muscle repair happens at night, better sleep means better preservation of lean muscle.
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🌿 Why Not B Vitamins?
B12 and other B vitamins are fantastic for energy, but they don’t protect muscle tissue during rapid weight loss the way glycine does.
Many patients already get B vitamins from their diet or supplements, but glycine provides a targeted benefit exactly where tirzepatide users need it most: maintaining muscle integrity.
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✨ The Bottom Line
We chose glycine because:
✔ It protects lean muscle
✔ Supports body composition
✔ Enhances metabolic health
✔ Complements tirzepatide’s mechanism beautifully
At IYKYK Aesthetics, our goal is not just weight loss — it’s healthy, sustainable, body-composition-friendly weight loss.
If you’re ready to start your journey with a science-backed plan that protects your muscle and your metabolism, we’re here to help. 💚