02/10/2026
Great Study on Ozone in Periodontal Therapy
To summarize… Key question:
Does adjunctive ozone therapy improve periodontal clinical parameters (probing depth, gingival inflammation, bleeding, plaque levels, and attachment loss) in patients with chronic periodontitis compared to conventional scaling and root planing (SRP) alone?
Results
Probing Depth reduction showed significant reduction in 655 total patients.
Interpretation: Ozone + SRP reduces pocket depth more than SRP alone, but variability in ozone application methods may influence results. Both ozone water and gas were studied. Ozone reduces gingival inflammation, likely due to its anti-inflammatory and antimicrobial effects.
Ozone showed no significant difference when looking at Bleeding on Probing.
Interpretation: Bleeding is usually caused by inflammation, but may also be influenced by systemic factors (e.g., smoking, diabetes) not fully controlled in studies.
Plaque Index & Clinical Attachment Level also showed no significant improvements. Interpretation: Ozone may not enhance plaque control or tissue regeneration beyond SRP alone. Ozone is antimicrobial, but once calculus starts to form, ozone alone is not enough to remove it.
Conclusions
Ozone therapy along with SRP is superior to SRP alone in reducing probing depth and gingival inflammation, suggesting benefits in pocket depth and inflammation control. No significant effects on BOP, PI, or CAL, indicating ozone may not improve all periodontal parameters. Ozone is safe & well-tolerated: no adverse events reported.
My interpretation: While ozone is an incredible antimicrobial gas that should absolutely be used in biologic periodontal therapy, it is not a cure all. To better address bone loss, gingival inflammation / bleeding, and overall periodontal health, I would utilize other adjuncts like oil pulling, salt water, colloidal silver, red/blue light therapy, and oral probiotics on top of professional hygiene cleanings.
therapy as a complementary approach in periodontal therapeutics
https://zurl.co/ZPZXr