01/10/2026
⬇️⬇️ This sounds really promising.
Research to prevent repeat heart attacks 🫀🧪
A treatment that targets the immune system could help stop repeat heart attacks in people who have recently had one, according to the results of an early-stage clinical trial run here in Cambridge.
Two years after joining the trial, none of the participants that received treatment had further heart attacks.
Sixty patients who had recently had heart attacks took part in the IVORY trial. Of these patients, 55 then participated in up to five years of follow-up health monitoring, known as IVORY-FINALE.
This includes Mark (pictured), from Fulbourn in Cambridgeshire, who had a heart attack in August 2022 while cycling home from the gym.
After initial tests at Addenbrooke's, he quickly received treatment here at Royal Papworth to have a stent fitted that opened a narrowed artery and restored blood flow to his heart. He has had no further heart attacks or symptoms since.
Mark said, “I was keen to join the trial. It wasn’t just the possibility that the treatment could stop me from having another heart attack. It was knowing the team would be closely monitoring my health, so they would probably spot it early if anything started to go wrong."
In the trial, low-dose treatment with a drug called aldesleukin helped patients to avoid further heart attacks by reducing inflammation in major blood vessels, while also reducing other signs of heart attack risk.
This trial is a superb example of collaboration between researchers at Royal Papworth, Cambridge University Hospitals NHS Foundation Trust, the University of Cambridge and others, as we look to bring tomorrow's treatments to today's patients. 💙
🔗 https://royalpapworth.nhs.uk/our-hospital/latest-news/targeting-immune-system-to-prevent-future-heart-attacks