07/19/2024
Could the SARS-CoV-2 virus trigger Hashimoto's and autoimmune disease? Is Long-COVID really an early-stage autoimmune disease that hasn't been detected?
In this episode of The Hashimoto's Doctor Functional Medicine Podcast, Dr. Shook explores the potential link between COVID-19 and the onset of Hashimoto's and other autoimmune diseases. Could the lingering effects of Long COVID be an early indicator of autoimmune conditions?
Dr. Shook delves into the latest research, discusses possible mechanisms, and offers insights into how understanding these connections can aid in better managing and preventing autoimmune diseases.
Read the research article mentioned in this episode here:
Reaction of Human Monoclonal Antibodies to SARS-CoV-2 Proteins With Tissue Antigens: Implications for Autoimmune Diseases by Aristo Vojdani, Elroy Vojdani, and Datis Kharrazian.
Here’s a summary of the specific tissues that showed cross-reactivity with COVID-19 protein antibodies and the potential autoimmune diseases that might be triggered:
- Mitochondrial antigen (M2): Primary biliary cirrhosis, other liver diseases, scleroderma.
- Actin: Autoimmune diseases affecting muscles, such as polymyositis.
- Extractable Nuclear Antigen (ENA): Systemic lupus erythematosus (SLE), mixed connective tissue disease.
- Nuclear Antigen (NA): Autoimmune diseases like SLE.
- Histone: SLE and other autoimmune diseases affecting the nucleus.
- S100B: Neurodegenerative diseases like Alzheimer's, multiple sclerosis.
- Myelin Basic Protein (MBP): Multiple sclerosis, other demyelinating diseases.
- Neurofilament Protein (NFP): Neurodegenerative diseases like ALS, Alzheimer's.
- Synapsin: Neurological disorders such as epilepsy, schizophrenia.
- Beta-amyloid Protein: Alzheimer's disease.
- Tau Protein: Alzheimer's, other tauopathies.
- Collagen: Rheumatoid arthritis, scleroderma.
- Alpha-myosin: Autoimmune myocarditis, other heart diseases.
- Thyroid Peroxidase (TPO): Hashimoto's thyroiditis, Graves' disease.
- Liver Microsome: Autoimmune hepatitis.
- Pyruvate Dehydrogenase (PDH) peptide: Primary biliary cirrhosis.
- Glutamic Acid Decarboxylase 65 (GAD-65): Type 1 diabetes, stiff-person syndrome.
- Insulin Receptor (Insulin-R): Type 1 diabetes.
- Phospholipid: Antiphospholipid syndrome.
- Transglutaminase-6 (tTG-6): Gluten ataxia.
- Transglutaminase-3 (tTG-3): Dermatitis herpetiformis.
- Transglutaminase-2 (tTG-2): Celiac disease.
- Intestinal Epithelial Cells: Celiac disease, other gastrointestinal disorders.
- Beta-catenin: Cancer, certain autoimmune diseases.
- Occludin and Zonulin (Occ + zon): Increased gut permeability, various autoimmune diseases.
- Claudin: Increased gut permeability, associated autoimmune diseases.
- Aquaporin-4 (AQP4): Neuromyelitis optica.
- Presenilin: Alzheimer's disease.
These findings highlight the potential for COVID-19 to trigger a variety of autoimmune conditions by causing the immune system to attack these tissues.
Unlock your path to better health with our free Hashimoto's Reset Protocol. This comprehensive approach is designed by Dr. Shook, a Certified Functional Medicine Clinician, who combines diet, lifestyle, and optional supplementation to support your thyroid health. Get started today and access everything you need through our easy-to-use app. Click here to begin your journey to better health! https://l.bttr.to/Gga9s
Would you like one-on-one help from Dr. Shook anywhere in the world via telemedicine and the option to order immune-based testing to identify your specific immune triggers? You can learn more on our website here https://drbradshook.com/new-patient-center-2/
Disclaimer: The information provided in this video is for informational purposes only and does not constitute medical advice. Always consult with your physician or a qualified healthcare professional before starting any new treatment or protocol. Dr. Shook is a Board Certified Chiropractic Physician with extensive training and qualifications in functional medicine. He is a Certified Functional Medicine Clinician through the Kharrazian Institute and is eligible for certification as a Functional Medicine Practitioner by the Institute for Functional Medicine. Additionally, Dr. Shook is eligible for a fellowship in Anti-Aging and Metabolic Medicine from the American Academy of Anti-Aging Medicine. He is also an Apollo Health Certified Practitioner, having completed ReCODE 2.0 training in the Bredesen Protocol for Cognitive Decline and Alzheimer’s.