Hoboken Functional Medicine

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Hoboken Functional Medicine

Our treatment focus is on nutrition, lifestyle, stress management, herbs & supplements, as well as m

09/13/2025

Risks of prebiotics and probiotics are nominal. Benefits likely clinically significant. Can we say the same for any of the prescriptions we use for PCOS?

For the record I use both. Maximize all the tools in our collective tool boxes.

“The prebiotics or synbiotics supplementation significantly reduced weight, BMI, WC, TG, LDL-C, HDL-C, hs-CRP, MDA, and total testosterone and increased HDL-C and TAC. Prebiotic supplementation for small periods (8 weeks) may have caused a significant improvement in obesity indices, lipid profile, and FPG. Probiotics led to significant reductions in insulin, HOMA-IR, and TG. Therefore, prebiotics or synbiotics can be recommended as a therapeutic approach for improving health outcomes in PCOS patients.”

https://www.sciencedirect.com/science/article/pii/S175646462500338X

08/01/2025

Larazotide is an 8 amino acid peptide taken orally, which was first studied for potential benefits in the celiac population. It antagonizes zonulin proteins that regulate tight junctions in the GI tract. Basically that means it can help heal a hyper-permeable intestinal lining (leaky gut). I’ve used it personally, with family and patients.

In this just published phase 2a randomized, double-blind, placebo-controlled clinical trial 12 children with MISC were treated with adjuvant larazotide therapy four times daily for 3 weeks. There was 24 weeks of safety monitoring. No larazotide-related adverse events were reported.

“The concentration of SARS-CoV-2 spike protein antigen in blood samples correlated with inflammatory markers, including interferon-γ and interleukin-6 and with gastrointestinal symptoms. Children treated with larazotide displayed faster resolution of gastrointestinal symptoms, faster clearance of spike antigen, and a faster return to usual activities.”

https://www.science.org/doi/10.1126/scitranslmed.adu4284

This is a small study. More are warranted. However from an overall risk benefit assessment it a very promising. Based on its mechanism of actions and the data we have to date, there are no downsides currently known.

My trusted source is Lvlup Health
I use code CHIARAMD for friends and family discounts

This post is for informational purposes only and not meant to be taken as medical advice.

03/13/2025

This is from 1 daily seltzer in aluminum cans x 2 months.

Lab result courtesy of my husband who didn’t believe me. 🤣

Plan of action:
1- stop drinking from aluminum cans
2- stop drinking from aluminum cans
3- stop drinking from aluminum cans

Then maybe consider a silica containing product of it doesn’t go to zero on its own (I prefer here)

03/08/2025

Thanks to my brilliant sister’s idea I finally was able to sneak some PC into my daughter 🤩🥰

I use a lot of high dose PC from in my practice as part of cellular detoxification support plans. In lower doses I still recommend for maintenance to replenish bioactive lipids and replace damaged cellular and mitochondria membranes. These are constantly being damaged by any inflammatory/oxidative inputs including aging, chronic infections, emf, microplastics and mycotoxins. These bioactive lipids also support the brain, liver, gallbladder and a healthy intestinal lining.

02/26/2025

Long overdue baby steps.

“Parents should know that when their children eat at school, they are getting real, nutritious food—not the kind of processed junk that’s banned in other countries. This is common sense”

“HB2164 prohibits the sale or serving of school foods that contain potassium bromate, titanium dioxide, brominated vegetable oil, propylparaben, and synthetic food dyes like Red 40 and Yellow 5—several of which are already restricted or banned in Europe due to harmful effects on children’s health.”

What say you New Jersey ?

11/07/2024

“According to a recent study, each cup of tea produced by one plastic tea bag steeped at brewing temperature included roughly 11.6 billion microplastics (MPs) and 3.1 billion nanoplastics (NPs)”

“Prior studies on animals have demonstrated that intestinal oxidative and inflammatory imbalance was brought on by exposure to NPs and MPs.”

“MPs include additives, adsorb pollutants, irritants, and the development of bacterial pathogens may occur on their surface, making them extremely dangerous to consume”

“Additionally, they carry intestinal toxins that disrupt intestinal processes and upset the balance of the organisms in the gut, perhaps setting the stage for the emergence of long-term immune system problems. A multiendpoint toxicological investigation on colorectal cancer cell lines revealed higher absorption and intracellular accumulation of MP and NP particles with regard to gastrointestinal cancer.”

Tea recommendations:
Organic, loose leaf or 100% plastic free bags

Brands I like:

https://pmc.ncbi.nlm.nih.gov/articles/PMC10389239/

10/30/2024

When I discuss this topic with patients (which is every single day for a decade now and side note it’s exhausting) I usually get one of three responses.

1- Oh my god we’re all gonna die! (panic)
2- Damn if they’re everywhere why bother? (avoidance)
3- Lady you’re nuts. (which may also be true)

For the record these 4 recommendations are ok but I teach it like this:

Clean water
Clean food
Clean personal care and household products
Clean indoor air

There are tons of resources to help navigate this path.

My 6 year old knows not to take the receipts!! That’s an extra goodie. Online shopping for the win 🥇

If you want to learn more I’d bet this episode will be worth the time.

10/19/2024

The future of medicine… has already been around for a long time, according to Hippocrates and the movement. About time the broader medical community catches up! And I’ll add as a plea to other medical practitioners- please stop passive aggressively putting the term dysbiosis in quotes as if it doesn’t exist. Have we forgotten how to search pubmed?!

https://www.medscape.com/viewarticle/how-future-medicine-will-revolve-around-our-gut-2024a1000h8m?ecd=mkm_ret_241019_mscpmrk_gastro_microbiome_etid6915264&uac=326383DX&impID=6915264

10/18/2024

The fact that medscape used this title. I’m 💀

At the end of the video where she talks about all the bad things ultra processed foods are associated with she turns the tables to discuss some studies with better outcomes and she uses the specific example of YOGURT. When the ** did yogurt become an ultra processed food. What are these people trying to prove?

https://www.medscape.com/viewarticle/ultraprocessed-foods-and-cvd-myths-vs-facts-2024a1000iqn?ecd=a2a

10/16/2024

Sometimes you gotta ask the tough questions 🙋🏻‍♀️ 🧐 💯

is just the start of this movement

08/11/2024

Interesting research, takeaways:
BPA free plastic is a meaningless label
All bisphenols are endocrine disrupting
Maternal exposure is detrimental to the fetus
Royal jelly may be beneficial in these cases

There’s a reason I flew with empty canteens that I’d fill from glass bottles at an airport restaurant when I was pregnant. Regardless of the crazy looks I got 😂

“Although bisphenol A (BPA) has been replaced by other bisphenols such as bisphenol S in BPA-free plastics, all bisphenols are endocrine-disrupting chemicals that can alter steroid signaling and metabolism. Elevated maternal prenatal BPA levels are associated with child neurobehavioral issues.”

“it is possible that estrogen supplementation, such as with 10-hydroxy-2-decenoic acid (10HDA), a major lipid component of the royal jelly of honeybees, may be relevant as a nutritional intervention for ASD.”

https://www.nature.com/articles/s41467-024-48897-8

07/01/2024

Yes they’re right. Sorry le creuset, this is now my favorite skillet. Bought as a gift but had a chip (on non-cooking surface) so they sent replacement for free and I got to keep this one for myself! This is not an ad I posted this because I love sharing amazing companies who make non toxic products for those of us who obsess over those things 🤷🏻‍♀️🥰

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http://hobokenfunctional.com/

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