
08/25/2025
I've been told my informative posts tend to be excessive. But I am an educator..and I've always believed knowledge and wisdom to take precedence over dumbing anything down. Especially in this day and age when our when our attention span is being conditioned for poor endurance (a sign of early neurodegeneration, by the way).
I will not enable the dumbing of society. So here we go...
Did you know your body has a detox superhighway just for estrogen?
Your estrogen isn’t just floating around—it's constantly being broken down and cleared by enzymes. Think of it like a relay race:
CYP enzymes decide one of these three paths:
✨️2-OH estrogens = anti-inflammatory, protective.
✨️4-OH estrogens = reactive + DNA-damaging if not neutralized.
✨️16-OH estrogens = growth-promoting, linked to fibroids + hormone chaos.
Then, COMT steps in to calm the fire—methylating harmful metabolites to make them safer.
Finally, UGT & SULT are the packaging crew—boxing everything up so your liver and gut can send estrogen OUT of the body.
But here’s the catch… 🚨
When SNPs (gene variants), toxins, or nutrient deficiencies slow this process, estrogen can pile up in the wrong lanes—leading to PMS, heavy periods, endometriosis, mood swings, and even higher risk states.
So, how do you support your estrogen detox crew? 👇
🥦 Foods that help:
Cruciferous veggies (broccoli, kale, Brussels) → boost CYP’s protective 2-OH pathway.
Green tea, rosemary → enhance COMT.
Citrus, berries, garlic, onions → fuel UGT & SULT.
High-fiber foods → help carry estrogen OUT through the gut.
☠️ Things that block the system:
Pesticides & herbicides 🚜
BPA & plastics 🥤
Obesogens (chemicals that promote fat gain + store estrogens)
Heavy alcohol use 🍷
Endocrine-disrupting cosmetics 💄
Your genes load the gun, but your lifestyle pulls the trigger. Supporting these enzymes = better hormone balance, mood, energy, and lower risk. 💪