01/16/2026
Chronic neuropathic pain in patients with Charcot-Marie-Tooth (CMT) disease is common and often overlooked.
CMT is a hereditary peripheral neuropathy characterized by progressive degeneration of the nerves that carry motor and sensory signals between the spinal cord and the limbs. This disease often leads to muscle weakness, sensory loss, and significant neuropathic pain.
While CMT traditionally has been viewed through the lens of motor dysfunction and sensory loss, neuropathic pain is increasingly recognized as a meaningful and often debilitating aspect of the disease.
Spinal cord stimulation is a proven interventional therapy that helps treat this chronic neuropathic pain, with published evidence demonstrating significant pain relief and improved quality of life following SCS implantation in patients with chronic pain due to this condition.
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