02/19/2026
Glutathione is often called the body’s “master antioxidant.” It’s a naturally occurring molecule made from three amino acids: glutamine, cysteine, and glycine. It plays a major role in cellular protection, detoxification, and immune health.
Here are the main benefits:
1. Powerful Antioxidant Protection
Glutathione neutralizes free radicals and reduces oxidative stress, which is linked to aging, chronic disease, and inflammation. It also helps regenerate other antioxidants like vitamins C and E.
2. Detoxification Support
It plays a key role in liver detox pathways (Phase II conjugation), helping the body eliminate:
• Heavy metals
• Environmental toxins
• Medications
• Alcohol byproducts
This is why it’s often associated with liver health.
3. Immune System Support
Adequate glutathione levels help:
• Support T-cell function
• Improve immune response
• Reduce excessive inflammation
Low levels are often seen in chronic illness and autoimmune conditions.
4. Skin Health & Brightening
Glutathione may:
• Reduce hyperpigmentation
• Promote a brighter complexion
• Decrease oxidative skin damage
It works partly by influencing melanin production.
5. Brain Health
It protects neurons from oxidative stress and may support cognitive function. Low levels have been observed in neurodegenerative conditions.
6. Mitochondrial & Energy Support
Because it reduces oxidative damage inside cells, it may help improve cellular energy production.
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Who May Have Low Glutathione?
Levels tend to decline with:
• Aging
• Chronic stress
• Alcohol use
• Chronic illness
• Poor nutrition
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Forms of Supplementation
• Oral glutathione (variable absorption)
• Liposomal glutathione (better absorption)
• IV glutathione (medical supervision)
• NAC (N-acetylcysteine) – precursor that helps the body make its own glutathione
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Safety
Generally considered safe when used appropriately, but high doses may:
• Cause GI upset
• Interact with certain chemotherapy agents
• Affect zinc levels