
10/08/2025
HOW CBC WORKS IN THE BODY
Cannabichromene (CBC) is one of the lesser-known cannabinoids, but its mechanism of action makes it particularly exciting to researchers. Unlike THC, CBC does not strongly bind to the CB1 receptors in the brain, which explains why it isn't intoxicating. Instead, it interacts with CB2 receptors found throughout the immune system and peripheral tissues, playing a role in regulating inflammation and pain responses.
What makes CBC stand out is its effect on the body's natural endocannabinoids. Research shows that CBC can inhibit the breakdown of anandamide, often called the "bliss molecule." By helping anandamide stick around longer, CBC may enhance mood and create a greater sense of balance without producing a high.
CBC also engages with TRPV1 and TRPA1 receptors - two receptors' families linked to how the body perceives pain, temperature, and inflammation. This interaction suggests a unique pathway for CBC in pain and inflammation support that sets it apart from other cannabinoids.
Though studies are still early, CBC's ability to work through multiple receptor systems - immune, mood, and sensory - makes it one of the most versatile non-intoxicating cannabinoids in the plant.