City of Hope Orange County

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Irvine, CA
City of Hope Orange County

Orange County’s most advanced cancer research and treatment.

03/06/2026

Happy Employee Appreciation Day. 💙

To every member of the City of Hope Orange County team — thank you for the care, compassion and dedication you bring to our patients and to one another. Because of you, hope lives here every day.

03/03/2026

The first human trials for bispecific antibodies happened at City of Hope, changing the field of blood cancer.

Today, this targeted immunotherapy continues to transform care for people with lymphoma and other blood cancers. Often delivered in an outpatient setting, bispecific antibodies help the immune system recognize and attack cancer cells — even in complex, recurring cases.

For some patients, this breakthrough has resulted in complete remission. And with it, renewed hope.💙

Learn more: https://bit.ly/4b985MC

02/23/2026

City of Hope is built on the dedication of people who care deeply about patients. From every role across our organization, compassion guides our work as we come together with one goal: to deliver hope and healing when patients need it most.

Eligible medical professionals can vote for City of Hope Comprehensive Cancer Center, a top cancer hospital, in the U.S. News and World Report rankings. Their vote can help give more tomorrows to patients and families who need lifesaving care.

02/20/2026

In 2018, City of Hope set a bold vision to motion: to bring world-class cancer care to Orange County. By 2019, that vision became a promise, unveiling plans for a second academic campus and comprehensive network in Orange County, made possible by the passion, partnership and belief of the community. Built with the community, for the community, this campus stands as a testament to what we can achieve together.

02/19/2026

Healing isn’t only about the care you receive — it’s also about the environment in which it happens. That’s why, at Orange County’s only cancer specialty hospital, every window and every view is thoughtfully designed to create a space that feels calm, grounded and supportive of the healing journey.

02/17/2026

Celebrating the Lunar New Year and welcoming the Year of the Fire Horse.🏮

The Horse represents energy, independence and bold forward momentum. As a Fire Horse year, 2026 carries added intensity and passion. A reminder that meaningful progress often requires courage, adaptability and decisive action. We embrace that spirit as we pursue breakthroughs, expand access to care and transform the lives of people with cancer. May this Lunar New Year inspire confidence, growth and renewed hope for the journey ahead. 💙

02/14/2026

They met at 19 in college. They fell in love, had a son, and then life pulled them apart for 40 years.

Cancer became a defining part of their journey. Michael survived pancreatic cancer, and Pamela is a double survivor — thyroid cancer and breast cancer a decade later. Genetic testing revealed that Michael carries the BRCA2 mutation and Pamela carries the BLM mutation — insights that shaped their care and ultimately became the thread that brought them all back together.

Decades later, their now-grown son took a DNA test — and it reunited the family. That reunion rekindled the connection between Michael and Pamela that had been lost for decades.

Soon after the reunion, Michael proposed. Pamela said yes, and their son stood beside them as best man.

“We feel reborn, with a new life,” said Michael. “Each of us has survived cancer. And we’re together!”

Today, they walk into City of Hope Orange County hand in hand. Survivors. Parents. Partners. Grateful for more time together. This Valentine’s Day, we’re celebrating this special love story. 💙

Their full love story: https://bit.ly/4qA8r4s

02/11/2026

Our wishing tree is more than branches and tags — it’s a living symbol of hope. 💙 Each note represents courage, dreams, and the strength of our community, reminding us that even in the toughest journeys, hope takes root and grows.

02/04/2026

On World Cancer Day, we’re looking ahead with optimism. People are living longer with cancer, with advanced disease increasingly managed as a chronic condition. New advances in cell therapies, AI, nutrition science and broader access to clinical trials are transforming care and expanding what long-term survivorship can look like. This is progress. This is hope. 💙

02/03/2026

On National Women Physicians Day, we celebrate the women physicians whose expertise and leadership are shaping the future of cancer research and treatment. Their work brings hope to patients and families across our community. 💙

01/29/2026

Morning light fills the lobby of Orange County’s only cancer specialty hospital. Every detail was carefully designed to bring comfort, hope and healing to our patients and their families. 💛

01/23/2026

A grateful patient wrote this team a heartfelt letter after receiving care at our new cancer specialty hospital. The team ensured the patient felt cared for every step of the way and welcomed her children as active members of her care team. Written with the help of her daughter, the letter now hangs in their office as a daily reminder that compassionate, inclusive care leaves a lasting impact — not just on our patients, but on their families too. 💙

Address

1000 FivePoint
Irvine, CA
92618

Telephone

+18883334673

Website

https://www.cityofhope.org/oc

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Our Story

The City of Hope story began in 1913, when a group of volunteers, spurred by compassion to help those afflicted with tuberculosis, established the Jewish Consumptive Relief Association (JCRA) and raised money to start a free, nonsectarian tuberculosis sanatorium.

After several fundraisers, the JCRA put a down payment on 10 acres of sun-soaked land in Duarte, where they would establish the Los Angeles Sanatorium a year later. The original sanatorium consisted of two canvas cottages. So was launched a century-long journey that would place City of Hope at the forefront of the nation’s leading medical and research institutions.

By the mid-1940s, thanks to the discovery of antibiotics, tuberculosis was on the decline in the U.S. However, City of Hope rose to the next medical challenge, tackling the catastrophic disease of cancer — and later on, diabetes and HIV/AIDS — while reaffirming its humanitarian vision that “health is a human right.”

In the spirit of that vision, Samuel H. Golter, one of City of Hope’s early leaders, coined the phrase, “There is no profit in curing the body if, in the process, we destroy the soul.” Those words became City of Hope’s credo.