https://linktr.ee/dr.felicegersh, https://integrativemgi.com/

Felice Gersh MD, 4968 Booth Circle, Irvine, CA (2025)

10/26/2025

🚨 4PM Pacific, Sunday
More than hot flashes: Sign you may be in perimenopause

Hot flashes and night sweats are a common and potentially debilitating symptom of perimenopause. But they are not the only symptom!

Let’s explore the many ways that dropping hormone levels can impact your body and overall wellness. And why recognizing and treating all of these symptoms is so important for long term health and quality of life.

⏰ Live Sunday, tune in for my talk.

Sun, 10/26 at 4:00 PM Pacific
Watch live on Instagram.
Or check YouTube for the recording in a few days.

I’ll be checking Instagram for questions so if you have any additional questions that you’d like me to address, please add them to the comments of this post.

Let me know what questions you have! And tune in for this upcoming talk!

10/24/2025

I had a wonderful time speaking at the .medicinaresolutiva conference in Mexico. And it’s always great to meet up with . Thanks to everyone who made this an unforgettable conference, overflowing with great people and great ideas!

10/24/2025

Observational? Yes. Ignorable? No.

This new analysis links perimenopausal estrogen use with ~60% lower odds of breast cancer, heart attack, and stroke vs non-users—while later starts help less. Timing matters.

My stance: Don’t wait for menopause or for severe hot flashes to “qualify.” I encourage women to discuss starting physiologic MHT in perimenopause, not only for vasomotor symptoms but also for brain, heart, and bone health.

Sources in Stories.
Contemporary OB/GYN: “Early estrogen use linked to lower disease risks.” (Oct 23, 2025)
https://www.contemporaryobgyn.net/view/early-estrogen-use-linked-to-lower-disease-risks/

10/23/2025

The Menopause Society’s 2025 Annual Meeting is happening now and a literature review was presented that links menopause to observable changes in brain structure that may correspond to vasomotor symptoms such as hot flashes and cognitive difficulties such as brain fog, mood disorders, and the development of dementia.

Of course we want more research to refine the details—but we don’t have to ignore the obvious driver: hormone loss. And the obvious therapy: hormones!

For most women, a physiologic, individualized HRT approach (transdermal estradiol + cyclic vaginal micronized progesterone) is a safe, beneficial path to support brain health during perimenopause and menopause.

https://www.contemporaryobgyn.net/view/menopause-linked-to-structural-brain-changes-tied-to-cognitive-and-emotional-symptoms/
Sources in Stories.

10/22/2025

Omega-3 is a critical supplement for menopause because...

Omega-3 is a critical fatty acid that our bodies simply can’t make—so we must get it from our diet.

EPA and DHA, the key forms of Omega-3, play powerful roles in supporting both the heart and the brain. And during menopause, that becomes especially important.

Women transitioning through menopause face higher risks of mood changes, anxiety, depression, and even dementia. Cardiovascular issues also rise—so Omega-3s are truly vital to help protect the heart, brain, and overall well-being.

To learn more, watch my full talk,
Best Supplements for Menopause: My Top 6 Picks for Energy, Focus & Longevity
youtu.be/FKKWEOcBAx0

10/22/2025

Omega-3 is a critical supplement for menopause because...

Omega-3 is a critical fatty acid that our bodies simply can’t make—so we must get it from our diet.

EPA and DHA, the key forms of Omega-3, play powerful roles in supporting both the heart and the brain. And during menopause, that becomes especially important.

Women transitioning through menopause face higher risks of mood changes, anxiety, depression, and even dementia. Cardiovascular issues also rise—so Omega-3s are truly vital to help protect the heart, brain, and overall well-being.

To learn more, watch my full talk,
Best Supplements for Menopause: My Top 6 Picks for Energy, Focus & Longevity
youtu.be/FKKWEOcBAx0

10/21/2025

Hormonal rhythms matter, and not just for fertility, because...
our bodies are optimized to cyclically alternate between growth and repair cycles.

We are rhythmic creatures. Just like we follow the cycles of the sun, and the seasons, our hormones also move in dynamic rhythms that keep us healthy and in balance.

Estradiol has the incredible ability to upregulate its own receptor function while also enhancing testosterone, progesterone, and thyroid receptor activity. This means your body becomes more responsive, more finely tuned, and more optimal when estradiol is in play.

Then progesterone steps in. It helps calm things down—downregulating estrogen and testosterone receptors, stopping excess growth, and restoring balance. This dynamic dance is how we achieve true hormonal harmony.

To learn more, watch my full talk,
Cyclic vs. Daily Progesterone: The Case for Rhythmic HRT
http://youtu.be/Fx7gtTOOLBk

10/21/2025

Cyclic human-identical progesterone is better than...
continuous progesterone or MPA (medroxyprogesterone acetate)

Many studies support cyclic progesterone use, not continuous. Remember, the progesterone we use today is real human bioidentical progesterone with powerful health benefits, unlike medroxyprogesterone acetate, the synthetic progestin used in the Women’s Health Initiative, which showed harmful effects early on.

Please don’t confuse the two as they are completely different. Bioidentical progesterone works with your body, while medroxyprogesterone is a toxic chemical that disrupts it. We want hormones that are human identical, not synthetic impostors.

And just as important—it’s not only about the amount, but the rhythm. Our hormones are meant to flow in cycles, up and down, to keep genes, receptors, and growth factors working in harmony. That’s how we keep our bodies functioning optimally, the way they were designed.

10/21/2025

Cyclic human-identical progesterone is better than...
continuous progesterone or MPA (medroxyprogesterone acetate)

Many studies support cyclic progesterone use, not continuous. Remember, the progesterone we use today is real human bioidentical progesterone with powerful health benefits, unlike medroxyprogesterone acetate, the synthetic progestin used in the Women’s Health Initiative, which showed harmful effects early on.

Please don’t confuse the two as they are completely different. Bioidentical progesterone works with your body, while medroxyprogesterone is a toxic chemical that disrupts it. We want hormones that are human identical, not synthetic impostors.

And just as important—it’s not only about the amount, but the rhythm. Our hormones are meant to flow in cycles, up and down, to keep genes, receptors, and growth factors working in harmony. That’s how we keep our bodies functioning optimally, the way they were designed.

10/17/2025

Cyclic progesterone in HRT isn’t new. And it wasn’t controversial until...

Really recently!!!

After the Women’s Health Initiative, two major hormone replacement therapy studies followed—KEEPS and ELITE. Both had flaws, but here’s the key takeaway: they used cyclic progesterone.

Cyclic progesterone never disappeared from the menopause research conversation. The original controversy came when continuous progestin—medroxyprogesterone acetate—was paired with conjugated equine estrogen (Premarin) in a single combo pill (Prempro). Somehow, that low-dose, continuous regimen became the default, but it’s not because that regimen was ever proven to be superior than cyclic.

The evidence consistently points back to cyclic progesterone as the physiologic, safer choice.

To learn more, watch my full talk,
Cyclic vs. Daily Progesterone: The Case for Rhythmic HRT
http://youtu.be/Fx7gtTOOLBk

10/17/2025

Cyclic progesterone in HRT isn’t new. And it wasn’t controversial until...

Really recently!

After the Women’s Health Initiative, two major hormone replacement therapy studies followed—KEEPS and ELITE. Both had flaws, but here’s the key takeaway: they used cyclic progesterone.

Cyclic progesterone never disappeared from the menopause research conversation. The original controversy came when continuous progestin—medroxyprogesterone acetate—was paired with conjugated equine estrogen (Premarin) in a single combo pill (Prempro). Somehow, that low-dose, continuous regimen became the default, but it’s not because that regimen was ever proven to be superior than cyclic.

The evidence consistently points back to cyclic progesterone as the physiologic, safer choice.

To learn more, watch my full talk,
Cyclic vs. Daily Progesterone: The Case for Rhythmic HRT
http://youtu.be/Fx7gtTOOLBk

Felice Gersh MD

10/26/2025

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