05/07/2026
Most people think detoxing means a juice cleanse for a few days. In my 30 years of functional medicine, I can tell you that is not how the body actually works.
Your liver runs two separate detox pathways, Phase I and Phase II, and they have to work together. If Phase I fires without Phase II being ready, you actually create more reactive, more harmful compounds in the process. That is not a cleanse. That is a burden.
Real detoxification starts with the gut. Before your liver can do its job, the intestinal lining has to be intact. When it is not, toxins that should be on their way out simply get reabsorbed. This is the part most protocols miss entirely.
I put together a free Detoxification Protocol guide that walks through exactly how I approach this with my patients, including the three pillars I use, the specific nutrients that support each phase, and the supplements I recommend most often.
You can download it here>>https://menoclinic.com/wp-content/uploads/Detoxification.pdf
If you are looking for a place to start, L-Glutamine is the first thing I reach for. It is the primary fuel source for the cells lining your gut wall, and repairing that lining is step one in any serious detox program.