
06/18/2025
This case includes the use of alpelisib for long-term treatment of tumor-induced hypoglycemia in 2 patients with insulin-producing or proinsulin-producing tumors.
Tumor-induced hypoglycemia (TIH) is a rare and often fatal complication of cancers that produce or induce secretion of hormones such as insulin, insulin-like growth factor 2, and proinsulin. We present a case series describing the effectiveness and tolerability of the phosphatidylinositol 3-kinase i...