11/20/2025
The U.S. released a study showing what most sensible people have always known: it is NOT SAFE to put on or give them to try to change their s*x.
The government calls this "s*x-rejecting procedures." The Biden administration called it "gender-affirming care." One of them is based in reality and the other is not.
The review examined the evidence behind , cross- *xhormones, and surgical interventions for and found the scientific support to be weak, inconsistent, or nonexistent. Long-term outcomes are largely unknown, the risks to fertility and bone development are significant, and the quality of most studies was rated “low” or “very low.”
The report makes clear that psychological support, not irreversible medical procedures, should be the first-line approach for children in distress. It warns that the medicalization of minors has outpaced the evidence, driven more by ideology and clinical momentum than by data.
Notably, the report does not address two of the most scientifically significant realities in this field: there are unusually high rates of autism and other neurodevelopmental conditions among gender-dysphoric youth. The report also omits longstanding research showing that most children with early-childhood gender dysphoria naturally resolve once they pass through puberty. Those omissions matter, because both factors dramatically affect diagnosis, treatment planning, and long-term outcomes.
This is very much in line with the UK’s Cass Report from 2024, which reached a similar conclusion after a years-long independent investigation: the evidence supporting pediatric gender-transition treatments is unreliable, the harms are under-studied, and mental-health evaluation must come before medicalization. Taken together, the Cass Report and the new HHS study form the strongest international repudiation yet of rushing children into life-altering procedures under the banner of “affirmation.”
