Rheumatology Winter Clinical Symposium

11/24/2025

Got tough clinical questions? RWCS 2026’s 'Ask the Consultant' connects you with top experts for real answers you can use today. Don’t miss it—register now: https://buff.ly/gpU2tnF

11/21/2025

Biopsy or ultrasound for GCA? The Great Debate at ACR heats up. Can one truly replace the other—or do we need both? Read more:

My favorite session at ACR Convergence is often the “Great Debate.” The debate this year also evaluated one of my favorite topics – ultrasound in giant cell arteritis (GCA). More specifically, it asked the question of whether biopsy or ultrasound should be the preferred modality for diagnosing...

11/18/2025

7-year RA and 2-year GCA data show upadacitinib’s safety is stable with thoughtful use. These results help move the conversation beyond just risk. Read more:

For the last several years, conversations about JAK inhibitors have often started and ended with safety. The shadow cast by ORAL Surveillance has made clinicians more cautious and regulators more restrictive. Yet in practice, many of us continue to reach for upadacitinib when we face challenges in t...

11/16/2025

IgG4-RD has new treatment options on the horizon—CD19 mAbs, BTKis, and JAKis show promise in trials. Read more:

IgG4 is a rare autoimmune disease with excessive IgG4 immunoglobulins that can affect multiple organs yielding plasma cell deposition (inflammation) and fibrosis.There has been great progress in treatment. Traditionally, glucocorticoids were used and if ineffective, then an oral immunesuppressive (e...

11/13/2025

Turn research into real-world impact. RWCS 2026’s 'Evidence-Based Medicine' gives you tools to treat with confidence. Register now: https://buff.ly/gpU2tnF

11/11/2025

New data show weight loss improves PsA outcomes—regardless of method. From GLP-1s to diet, BMI reduction consistently boosts response. Read more:

Psoriatic arthritis (PsA) is a complex inflammatory disease often complicated by obesity, which not only worsens disease activity but also impairs treatment response. At ACR Convergence 2025, three compelling studies spanning pharmacologic, lifestyle, and longitudinal observational data converged on...

11/09/2025

CAR-T shows promise in RA—but who gets access? New data expose major equity gaps and high costs:

At ACR Convergence 2025, abstract 1039 entitled, “Global Cost-Effectiveness and Equity in CAR-T Cell Therapy for Rheumatoid Arthritis” adds a critical dimension to the growing enthusiasm around cellular therapies in autoimmune disease.

11/07/2025

Do you have a rheumatology question or case for Dr. Cush? Record it today and you might be featured in an upcoming podcast episode!

Record a Question or Comment... Got a Rheumatology question or case for Jack Cush? Record it here and we'll feature it on an upcoming podcast. Tell us your name and where you practice rheumatology.

11/04/2025

Two positive Phase 3 trials in Sjögren’s disease—ianalumab and telitacicept show real promise after years of setbacks. Read more about this turning point:

After several failures of therapies in Phase 3 trials of Sjogren’s disease (SjD) over many years, all hope is not lost! At this year’s ACR25 Convergence Conference in Chicago, not one but two drugs presented their efficacy and safety data in patients with moderate to severe disease activity as d...

11/01/2025

Oral IL-23R blockade? Icotrokinra shows robust skin clearance and early promise in PsO and PsA—backed by strong safety data. Read More:

A new player is entering the IL-23 arena — and it’s a tablet! Icotrokinra (ICO), a first-in-class peptide that binds and blocks the interleukin-23 receptor (IL-23R), is showing encouraging efficacy and safety across a range of psoriasis (PSO) and psoriatic disease (PsD) studies.

10/30/2025

What’s next in rheumatology? RWCS 2026 explores future therapies + autoimmune breakthroughs you won't want to miss. Be one of the first to know—register now: https://buff.ly/gpU2tnF

10/27/2025

Systematic review and meta-analysis highlight HRCT as a key tool for diagnosing and characterizing ILD in CTD patients. Findings support its diagnostic value across CTDs.

A systematic review and meta-analysis examined the role of high-resolution computed tomography (HRCT) in diagnosing and characterizing interstitial lung disease (ILD) associated with connective tissue diseases (CTDs). The study analyzed 23 studies published between 2015-2024, encompassing 2020 patie...