04/26/2026
Is a more flexible GLP-1 always a better option?
In this episode, I’m breaking down different GLP-1 medications and here, I’m focusing on Foundayo (Orforglipron).
This is a non-peptide, synthetic oral GLP-1, which makes it more resistant to breakdown in the stomach.
So practically:
✔️ Higher bioavailability
✔️ No fasting requirements
✔️ No strict timing or food restrictions
And while that makes it easier to take, it’s also not a full GLP-1 receptor agonist — which is an important distinction when comparing it to other treatments.
I break all of this down in this week's episode, including how I think about using each option in practice.
🎧 Don’t miss this one — this is where the conversation around oral GLP-1s is heading.
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