Leigh Erin Connealy, M.D.

Leigh Erin Connealy, M.D. Leigh Erin Connealy, M.D. is a prominent leader in the field of Integrative Medicine. Dr. Connealy began practicing medicine in 1986.

She is the Medical Director of Cancer Center for Healing and Center for New Medicine, and the author of The Cancer Revolution. Leigh Erin Connealy, MD attended the University of Texas School of Public Health, and then attended the University of Health Sciences Chicago Medical School. She completed her post-graduate training at the Harbor/UCLA Medical Center in Los Angeles, California. Dr. Connealy

soon realized that conventional medicine had very limited returns and did not always improve the health of her patients. Her patients were hungry for alternative approaches for improving their health. This led her to study integrative and complementary therapies, and since then she has revolutionized the landscape of medicine. Dr. Connealy feels that we must treat the patient with the disease and not the disease of the patient. She has discovered that many factors contribute to the disease process; therefore, many modalities must be used to reverse it. Dr. Connealy treats the WHOLE person, and is open to all potential treatment possibilities. She has over twenty years of experience in finding the ‘root cause of an illness’, and has taken numerous advanced courses, including homeopathic, nutritional and lifestyle approaches, while studying disease, chronic illness, and cancer treatments. She has a true passion to change her patients’ lives, and give them their life back. In 1992, she founded the Center for New Medicine in Irvine, California, where she serves as Medical Director. Her practice is firmly based in the belief that strictly treating the health problems with medications does not find the root cause of the illness. The Center offers a vast array of services for men, women and children, including detoxification, holistic dentistry, nutrition, fitness and weight loss, cosmetic/laser treatment, pain management, allergy therapy, acupuncture, massage therapy, hyperbaric oxygen therapy, sleep disorders, and much more. We also provide specialized services in gynecology, natural fertility, menopause, hormone imbalances for all ages, healthy sexuality, healthy aging, and personalized preventive medicine. Some of the chronic conditions treated at the clinic include cancer, heart disease, diabetes, neurological and auto-immune disorders. Dr. Connealy writes and has been published in monthly health columns for "Coast" and "OC Health", Orange County based magazines and is published in "The Journal of the American Nutraceutical Association" (JANA), along with Healthy Aging Magazine. She is a frequent writer for Natural News. She is also a weekly co-host on Frank Jordan’s national radio show "Healthy, Wealthy and Wise" on Sirius/XM Channel 131 digital cable, KSPA 1510 AM, and WAVA 780. Dr. Connealy is a frequent guest speaker at professional organizations and on local cable television shows when highlighting health topics like KTBN or Know the Cause with Doug Kaufman airing across the country periodically. She has a weekly publication newsletter with Newport Natural Health and Eagle Publishing. To learn more about Leigh Erin Connealy, M.D. we invite you to visit www.centerfornewmedicine.com or www.perfectlyhealthy.com or www.connealymd.com or www.newportnaturalhealth.com.

6 Hughes • Suite 100 • Irvine • California • 92618 949.680.1880 • 949.680.1881 fax www.centerfornewmedicine.com • info@cfnmedicine.com

04/22/2026

Plastic is one of the most pervasive pollutants we face today. They are found in nearly every aspect of our environment— our water, food, clothing, the air we breathe, etc. These tiny plastic particles are released from food packaging, plastic bottles, and synthetic clothing fibers, do not easily break down, and can accumulate in our bodies over time.

Microplastics have the ability to act as endocrine disruptors. They contain chemicals like bisphenol A (BPA) and phthalates, which can mimic or interfere with natural hormone function, potentially leading to reproductive issues, metabolic disorders, and an increased risk of cancer. Microplastics also damage cell membranes, contribute to oxidative stress, and may be linked to long-term carcinogenic effects (PMID: 34326264).

Its important to note that BPA-free plastic can still be estrogenic. A 2011 study found that more than 70% of plastic products release chemicals that act like estrogen, even in products that don’t contain BPA (PMID: 21367689)

Reducing plastic exposure is important for cancer prevention. Although it might seem daunting, ,there are so many things we can do! Stopping exposure is one of the most important steps. Filtering drinking water, avoiding plastic packaging, and opting for natural fiber clothing are just a few ways to minimize exposure. Even though it takes some effort, small lifestyle changes can significantly reduce the impact of plastic on our bodies and the environment.

Some other tips:

⁃Use glass food containers
⁃Use glass water bottles
⁃Use parchment/ wax paper
⁃Vacuum frequently
⁃Never heat up plastic
⁃Look for 100% cotton, linen, wool, etc. clothing
⁃Use an air purifier
⁃Avoid processed foods

Some options for detox:

⁃Sauna
⁃Exercise to sweat everyday
⁃Take hot baths (ideally sweating)
⁃Blood phlebotomy

Small changes make all the difference!

04/21/2026

This is my go to. A big part of nutrition should be enjoying what you eat! Our bodies instinctively tell us what we need. ❤️

04/17/2026

10 things you won’t see me do as a doctor who treats cancer:🩺

1. Cook with aluminum or Teflon. Aluminum can leach into food, especially with acidic ingredients, and accumulate in tissues, contributing to oxidative stress. Teflon (PTFE) releases PFAS compounds when overheated—chemicals linked to thyroid dysfunction and cancer.

2. Estrogen and progesterone are meant to work in balance. Estrogen stimulates growth and cell division, while progesterone keeps that growth in check and supports differentiation. Taking estrogen alone—without progesterone to oppose it—can promote tissue proliferation, water retention, and inflammation, especially in breast and uterine tissue. In my view, unopposed estrogen is one of the most overlooked contributors to hormonal cancers and mood disorders in women.

3. Industrial seed oils (canola, soybean, sunflower, safflower, corn) are high in unstable polyunsaturated fats (PUFAs). When heated, they oxidize easily and form toxic aldehydes that damage mitochondria and cell membranes. I stick with saturated fats like coconut oil, butter, and tallow, or monounsaturated fats like olive oil—stable sources that support metabolic health and hormonal balance.

4. Phones emit electromagnetic frequencies (EMFs) that can damage cells. I charge my phone in another room and keep my sleep environment as free of digital noise as possible. Deep, restorative sleep is one of the most powerful anti-cancer therapies available.

5. When plastic is heated, it releases xenoestrogens—synthetic chemicals that mimic estrogen in the body. These compounds interfere with hormone receptors and have been linked to reproductive disorders and cancer. I reheat food in glass or ceramic instead. It’s a small change that makes a big difference in reducing toxic load.

Continued in comments…😃

04/17/2026

Progesterone is one of the most important hormones in the human body, yet it is also one of the most misunderstood. For decades it has been overshadowed by confusion around synthetic progestins, misconceptions about hormone therapy, and a tendency to reduce hormones to overly simple narratives. As a result, many physicians rarely consider progesterone outside of fertility or pregnancy, despite its broad effects on the brain, metabolism, inflammation, and tissue health.

Progesterone is not a rare or experimental compound. It is an inexpensive hormone the body naturally produces and that has been studied for decades.

We know mechanistically that progesterone has several anticancer effects. Progesterone:

🤍Induces cellular differentiation. It encourages cancer cells to mature into more specialized, less aggressive forms.
🤍 Inhibits cell proliferation. Progesterone slows down the rate at which cancer cells divide, partly by suppressing growth-promoting genes like cyclin D1 and MYC.
🤍 Reprograms estrogen receptor activity. It alters how estrogen receptors bind to DNA, reducing estrogen’s tumor-promoting signals in ER+/PR+ cancers.
🤍 Promotes apoptosis. It triggers programmed cell death by upregulating p53 and downregulating survival genes like BCL-2.
🤍 Improves mitochondrial function. It supports cellular energy production and reduces oxidative stress by enhancing mitochondrial efficiency and promoting a shift away from glycolysis toward oxidative phosphorylation.
🤍 Reduces inflammatory signaling. It suppresses inflammatory mediators like IL-6, COX-2, and TNF-α, which contribute to tumor growth and immune evasion
🤍 Stabilizes the tumor microenvironment. It helps maintain tissue integrity and reduce oxidative stress, creating a less favorable environment for cancer growth.

Continued in the comments…

04/16/2026

Ki-67 is a protein found inside cells that appears only when cells are actively dividing. Because of this, it’s used as a marker of cell proliferation.

Doctors look at a tumor sample under a microscope and calculate the percentage of cells that are Ki-67 positive:

🔬Low Ki-67 ( 20–30% or higher) → fast-growing, more aggressive tumor

This 41 yo breast cancer patient came in with a Ki-67 of around 30% and following lifestyle changes (diet and nutrition, addressing hormones, light environment, sleep, infections, toxicity, digestion, tissue oxygenation, etc.) was able to get it down to less than 10%! 💪

We want to look at all the root causes in addition to the tumor so we can prevent recurrence and heal the environment that allowed the cancer to grow in the first place.

04/16/2026

A 2024 study analyzing U.S. cancer incidence data from 2016 to 2020 found that higher solarUVB exposure was significantly associated with lower incidence rates of several internal cancers, including:

* ��Bladder
* ��Brain (in males)
* ��Breast
* ��Endometrial
* ��Esophageal
* ��Gastric (stomach)
* ��Non-Hodgkin’s lymphoma
* ��Pancreatic
* ��Renal (kidney)
(PMID: 38794688).

According to data from the Centers for Disease Control and Prevention (CDC), states with higher sun exposure, such as New Mexico and Arizona, report some of the lowest cancer incidence rates in the United States:

🏜️New Mexico: Approximately 381.0 cases per 100,000 people people
🏜️Arizona: Approximately 379.5 cases per 100,000

This is notably below the national average of 450.8 cases per 100,000 people.

“Studies in the past decade indicate that insufficient sun exposure may be responsible for 340,000 deaths in the United States and 480,000 deaths in Europe per year, and an increased incidence of breast cancer, colore**al cancer, hypertension, cardiovascular disease, metabolic syndrome, multiple sclerosis, Alzheimer’s disease, autism, asthma, type 1 diabetes and myopia.” (PMID:
32668607).

A lot of data suggests that consistent sun exposure is protective, rather than intermittent, intense exposure.

Obviously, this topic is nuanced because we are often told to stay out of the sun. However, the human body is more complex than black-and-white statements.
In our efforts to avoid the sun (more so than any generation before us), rates of cancer continue to rise.

We are designed to receive the sun’s inputs. Achieving a balance between safe sun exposure and protection from harmful UV rays is key to maintaining health and connection to nature. It’s important to make peace with our environment. 🌞🌞🌞

04/15/2026

MASA Chips are always a fan fav! 🍎

04/14/2026

Underrated practices for cancer prevention!!

▫️Aspirin (when needed). Lowers inflammation, prevents lipolysis, blocks COX enzymes, helps restore glucose oxidation, and prevents metastasis. Linked to lower risk of colore**al, breast, brain, ovarian, prostate, and other cancers (PMID: 39923320).

▫️Coffee. Rich in antioxidants, helps detoxify, and linked to lower risk of thyroid, liver, endometrial, and colore**al cancers (PMID: 36769029).

▫️Sun. Exposure to UVB light boosts vitamin D, infrared light enhances mitochondrial function, regulates immune cells. Linked to lower incidence of breast, brain, colon, bladder, pancreatic, stomach, Non-Hodgkin’s lymphoma, kindey and other internal cancers (PMID: 38794688).

▫️Milk. A 2025 study found a 17% lower risk of colore**al cancer per 300mg/day of calcium intake. Predicted milk consumption (200g/day) was associated with: 40% reduction in colore**al and colon cancer risk and a 51% reduction in re**al cancer risk (PMID: 39779669).

▫️Warm baths/sauna. Cancer cells are very sensitive to heat, which is why hyperthermia is a common adjunct cancer therapy. Heating the body can induce mild hyperthermia, improve immune function, promote detoxification, and reduce systemic inflammation.

▫️Avoiding artificial light. A 2016 study concluded, “artificial light at night is significantly correlated for all forms of cancer as well as lung, breast, colore**al, and prostate cancers individually” (PMID: 27892680). Using candles or incandescent bulbs, sleeping close to sunset, and avoiding screens can help avoid exposure.

▫️Nasal breathing. Supports CO2retention, which improves oxygen delivery to tissues via the Bohr effect. Cancer usually grows in areas of low oxygen, so nasal breathing can help maintain oxygen levels.

▫️Coconut oil. Rich in lauric acid which is converted into energy by the liver & stable at high heat. In 2022, researchers found that lower levels of lauric acid may be associated with a higher risk of breast cancer (PMID: 36558514).

▫️Sunrise and sunset. Higher exposure to infrared and red light supports mitochondrial function and cellular repair. ☀️🤍

04/13/2026

My morning stack! I get my juice delivered from www.earthlyjuicecart.com and all the supplements can purchased from Perfectly Healthy ! 🍊🌱

04/13/2026

In the United States alone, nearly 90 million people are taking statins, yet heart disease remains the leading cause of death. If lowering cholesterol were the full solution, we would expect to see a far greater reduction in cardiovascular mortality—but the data suggests the story is more complex.

We have to start asking a better question: why is cholesterol elevated in the first place? The body does not act randomly. Elevated cholesterol is often a response to underlying dysfunction, not the root cause itself.

Cholesterol is not inherently harmful. It is biologically essential, serving as the foundation for all steroid hormones, supporting cell membrane integrity, and functioning as part of the body’s antioxidant and repair systems. In many cases, the body may increase cholesterol production in response to stress, inflammation, or metabolic imbalance.

Moreover, some research has shown that lower cholesterol levels are associated with higher all-cause mortality, particularly in certain populations (PMID: 21160131, 34764414), raising important questions about the risks of aggressively lowering cholesterol without addressing underlying causes.

If we want to truly prevent cardiovascular disease, we need to shift the focus from simply lowering cholesterol to understanding what is driving its elevation—including thyroid function, insulin resistance, inflammation, oxidative stress, and vascular damage.

Here are key factors I evaluate: 🫀

Continued in the comments…

04/10/2026

Simple and fresh!🍅🤍

04/09/2026

I think it’s always important to remember that everything in the body is connected. We are not just a set of systems! Our oral health is closely tied to other areas in the body including the brain, lymph system, breasts, and digestive organs. For anyone looking for holistic dental care, Holistic Dental Arts in Orange County is my rec! 🦷🪥

Address

Lake Forest, CA

Opening Hours

Monday 8:30am - 5pm
Tuesday 8:30am - 5pm
Wednesday 8:30am - 5pm
Thursday 8:30am - 5pm
Friday 8am - 4pm

Telephone

+19496801880

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