NovaSterilis

NovaSterilis NovaSterilis uses supercritical CO2 solutions to promote safe, innovative products and improve lives.

NovaSterilis is the global leader in the development and manufacturing of supercritical carbon dioxide (scCO2) processes for biomaterials and medical devices, including the decellularization and sterilization of allograft and xenograft tissues. At its core, NovaSterilis is a team of scientists, engineers, and business people committed to meeting our customers' needs through problem-solving. Our multi-disciplinary team of engineers, biochemists, and molecular and cellular biologists bring their broad and deep knowledge to every development challenge. We have the team, equipment, and processes readily available to provide scCO2 solutions that enable the implementation of manufacturing solutions that meet product safety requirements and performance and enable our partners to deliver safe, innovative products that advance patient healing and outcomes. With NovaSterilis you can count on a sterility assurance level 10-6, an environmentally friendly solution, shorter turnaround times, and more. Protect and differentiate your products with supercritical CO2.

The   delivers supercritical CO2 performance in a 60 lb., 24”x20”x12” package that is engineered for versatility and pre...
10/27/2025

The delivers supercritical CO2 performance in a 60 lb., 24”x20”x12” package that is engineered for versatility and precision at lab scale to give researchers the control and repeatability they need. Learn more about this system: https://bit.ly/3Ow1SA6

Dive into each stage of the   process, from liquid fill to supercritical transition and return to ambient conditions.  T...
10/24/2025

Dive into each stage of the process, from liquid fill to supercritical transition and return to ambient conditions. This is a look inside the pressure vessel- you can see the supercritical CO2 process—it will get you thinking of the possibilities..

Watch the process in full:

This short timelapse provides a complete perspective of the supercritical CO₂ sterilization process. Watch as the chamber:• Starts clear and empty• Fills wit...

Allograft tendon sterilization SAL6, full cycle 240 minutes.   sterilization is providing clinicians with sterile soft t...
10/23/2025

Allograft tendon sterilization SAL6, full cycle 240 minutes. sterilization is providing clinicians with sterile soft tissue. This study provides process and methods insight with results confirming SAL6 terminal sterility. Med Device and Tissue Banks can draw on this work for their manufacturing process development. Read more: https://bit.ly/3UxVdc3

Balancing sterility assurance with material compatibility is a persistent challenge in   manufacturing. Discover how   s...
10/22/2025

Balancing sterility assurance with material compatibility is a persistent challenge in manufacturing. Discover how sterilization can be an alternative to and traditional terminal methods:

As device complexity increases, supercritical CO₂ is redefining sterilization - going beyond the limits of aseptic manufacturing. Learn more.

Selecting the right   modality can directly influence data integrity and material performance in R&D environments. Learn...
10/21/2025

Selecting the right modality can directly influence data integrity and material performance in R&D environments. Learn how systems enable contamination control for temperature-sensitive materials and complex biomaterials: https://bit.ly/3Bk6t4l

Achieving sterility assurance level 10-6 is a necessity for advanced   and  . NovaSterilis’   approach offers deep pe***...
10/20/2025

Achieving sterility assurance level 10-6 is a necessity for advanced and .

NovaSterilis’ approach offers deep pe*******on, short cycle times, and compatibility with sensitive materials. Explore how this terminal solution is helping innovators move from proof of concept to regulatory approval: https://bit.ly/42XHtrP

As combination drug-delivery products become more complex, traditional   methods can compromise material integrity and t...
10/17/2025

As combination drug-delivery products become more complex, traditional methods can compromise material integrity and therapeutic function.

NovaSterilis’ process preserves both physical and biologic properties while enabling uniform bioactive deposition. Explore more: https://bit.ly/40fUNbI

  and   are tightly connected as materials must allow effective sterilization while maintaining barrier integrity. For s...
10/16/2025

and are tightly connected as materials must allow effective sterilization while maintaining barrier integrity. For sensitive devices and biologics, requires compatible, gas-permeable packaging. Read our full blog to explore best practices and considerations: https://bit.ly/3zyKeXr

This study dives into a novel   method using   and   that showed promising results for preserving key growth factors in ...
10/15/2025

This study dives into a novel method using and that showed promising results for preserving key growth factors in amniotic membrane allografts, which provides a powerful alternative to irradiation. Read the full study: https://bit.ly/41nAd9L

Overkill, bioburden-based, and combined validation methods offer different balances of microbial reduction, material imp...
10/14/2025

Overkill, bioburden-based, and combined validation methods offer different balances of microbial reduction, material impact, and process complexity. For temperature-sensitive devices, supercritical carbon dioxide enables effective at mild conditions. Learn more:

Strong Bioburden control processes give device manufacturers more flexibility when choosing sterilization validation strategies. Read more.

Discover the power of   sterilization as a sustainable and effective method for processing  ,  , and proteins in therape...
10/13/2025

Discover the power of sterilization as a sustainable and effective method for processing , , and proteins in therapeutic drugs and medical devices. Download NovaSterilis' Therapeutic Sterilization Compatibility Guide today: https://bit.ly/45HI7ux

Traditional   methods present limitations for the tissue bank industry.   offers a proven alternative that delivers term...
10/10/2025

Traditional methods present limitations for the tissue bank industry. offers a proven alternative that delivers terminal sterilization while preserving the native structure and function of allograft tissue.

Connect with our team to discuss how can advance your tissue sterilization process: https://bit.ly/3Cz9oU5

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3109 North Triphammer Terrace
Lansing, NY
14882

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