02/05/2026
If depression symptoms keep returning, or never fully lift, even after trying treatment, it may be time to ask a different question. Not every low mood is TRD, but persistent symptoms deserve a full medical review.
Treatment resistant depression is often used when two or more antidepressants have not helped enough, despite being taken correctly and for long enough. At Heal + Glow Wellness, our clinicians look at the full picture, including medication history, sleep, stress, hormone health, and other medical factors that can affect mood, so you are not guessing your next step.
Learn more about TRD and your options at healandglowwellness.com. If you are in crisis, call or text 988, or contact your local emergency services.