Biolexis Therapeutics

02/04/2026

In this episode of the Good Medicine Podcast, Dr. David Bearss sits down with Dr. Jim Hotaling and Dr. Brad Cairns from Paterna Biosciences to talk about a new way of thinking about male infertility.

Dr. Brad Cairns explains that in many cases, stem cells themselves are not the root of the problem. Instead, the issue lies in the supporting or chaperoning cells that guide stem cells through normal development. Paterna’s work focuses on restoring that developmental process rather than replacing cells outright.

The conversation also explores how Paterna is developing approaches to help men with infertility at many different stages, offering options even when traditional treatments have failed. Dr. Jim Hotaling shares the deeply personal side of this work, reflecting on his role in delivering life altering news to families and how that responsibility drives his commitment to building better solutions.

This episode blends cutting edge science with the human reality behind infertility and why progress in this space matters so much.

In this episode of the Good Medicine Podcast, Dr. David Bearss sits down with Dr. Jim Hotaling and Dr. Brad Cairns from Paterna Biosciences to talk about a n...

01/09/2026

https://www.biospace.com/press-releases/biolexis-therapeutics-to-present-at-j-p-morgan-healthcare-conference

Company to Highlight the complete solution to the GLP-1 weight regain crisis: Only All-Oral Dual-Mechanism Metabolic Platform in Clinical Development, Featuring First-in-Class Oral GLP-1 Agonist and Muscle-Selective AMPK Activator

12/16/2025

This week on the Good Medicine Podcast, we are sharing a prerecorded panel hosted by Dr. David Bearss at the BioUtah Life Science Summit. The panel brings together leaders from across the industry, including Hariprasad Vankalapati of Biolexis, Alison O’Mahony of Seek Labs, and Ian Quigley of Leash Bio.

Together, they discuss how artificial intelligence is beginning to reshape drug discovery, diagnostics, and the way companies make decisions. The conversation highlights how AI helps teams understand both positive and negative data, identify emerging threats, and improve the success rate of bringing new drugs to market. This panel offers a grounded look at how AI is being used in real life science organizations today and what the future may hold.

This week on the Good Medicine Podcast, we are sharing a prerecorded panel hosted by Dr. David Bearss at the BioUtah Life Science Summit. The panel brings to...

12/09/2025

This week on the Good Medicine Podcast, Dr. David Bearss speaks with Dr. Karson Kump of Aditum Bio, an organization focused on advancing treatments for unmet medical needs by guiding programs through development with a disciplined, data-driven approach.

Dave opens the discussion by explaining how business development in life sciences is really about resource allocation. Scientists often follow what interests them, but companies must stay focused on what patients actually need and where the biggest gaps in medicine still exist.

Karson shares how spending enough time in science humbles you. He explains that good decisions come from yielding to the science and letting objective data lead the way. At the same time, choosing to take a program outside your own company and into the world of partnerships can feel risky, even though it may be the best path forward.

The conversation ends with Dave reflecting on ego, humility and delegation. In a field filled with smart, driven people, he has learned that real success comes from knowing when to step back and let someone who is better at a specific task take the lead.

This week on the Good Medicine Podcast, Dr. David Bearss speaks with Dr. Karson Kump of Aditum Bio, an organization focused on advancing treatments for unmet...

12/02/2025

https://www.biospace.com/press-releases/biolexis-therapeutics-vp-of-clinical-development-selected-for-dual-featured-presentations-at-the-2nd-innovation-in-obesity-therapeutics-summit

Dr. Jeremiah Bearss, MD, PhD, to Present Groundbreaking Research on Exercise Mimetics and Lead Panel Discussion on Redefining Success in Obesity Care

12/02/2025

This week on the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss explore what fat is actually communicating to your brain and why the body often fights against weight loss.

Jeremiah explains how the body is wired to hold onto fat as a survival mechanism. Fat storage has always been the backup plan for famine, injury, and cold, which means the body’s default mode is to protect those reserves in case something goes wrong.

Dave discusses how inflammation influences this process. When the body is inflamed, fat can send signals to the brain that increase appetite and encourage the body to store even more fat. Reducing inflammation can help reverse that signal and make it easier to lose weight and keep it off.

They also talk about the many different GLP-1 targets currently being explored and why inflammation may be the reason these drugs work for so many people. Jeremiah explains how the next phase of drug development and health innovation will likely focus on shifting the course of the obesity crisis.

This week on the Good Medicine Podcast, Dr. David Bearss and Dr. Jeremiah Bearss explore what fat is actually communicating to your brain and why the body of...

12/01/2025

Tomorrow on the Good Medicine Podcast, Jeremiah Bearss explains why the body is designed
to hold onto fat.

Fat storage is the backup system for famine, injury, and cold, and the body protects it in case
something goes wrong.

11/26/2025

This week on the Good Medicine Podcast, Dr. David Bearss sits down with Dr. Christin Glorioso of NeuroAge to explore new ideas in brain health and aging.

Dr. Glorioso explains how NeuroAge’s comprehensive test measures your brain’s “age” and provides personalized recommendations to help you work toward reversing brain aging. She also talks about how aging itself is not a disease, but how aging increases the risk for many diseases such as Alzheimer’s, and why understanding brain age matters for long-term health.

She also shares her interest in GLP-1 drugs and how she uses microdosing as part of her personal brain-health approach.

This episode blends science, innovation, and practical strategies for anyone interested in staying mentally sharp as they age.

This week on the Good Medicine Podcast, Dr. David Bearss sits down with Dr. Christin Glorioso of NeuroAge to explore new ideas in brain health and aging.Dr. ...

11/24/2025

Tomorrow on the Good Medicine Podcast, Dr. Christin Glorioso from NeuroAge explains how
their brain-age test works and how personalized recommendations can help you start reversing
brain aging.

11/21/2025

On the Good Medicine Podcast, Dr. David Bearss sits down with Zeke Misner of Medix Life Sciences to talk about improving access to care, speeding up innovation, and using AI responsibly in the life sciences industry.

Dave opens the conversation by emphasizing that where you live or your ZIP code should not determine your health outcome. Zeke shares how technologies like artificial intelligence and data-driven processes are helping companies like Medix accelerate progress while maintaining strong ethical standards.

Whether you’re interested in healthcare access, life sciences operations, or how AI is shaping the future of medicine, this episode offers both practical insights and big-picture perspective.

This week on the Good Medicine Podcast, Dr. David Bearss sits down with Zeke Misner of Medix Life Sciences to talk about improving access to care, speeding u...

10/29/2025

https://www.biospace.com/press-releases/biolexis-therapeutics-to-present-groundbreaking-data-on-first-in-class-dual-mechanism-oral-therapy-for-obesity-at-obesityweek-2025

Novel Combination of Oral GLP-1 Receptor Agonist BLX-7006 and γ3-Selective AMPK Activator BLX-0871 Demonstrates Superior Weight Loss with Unprecedented Muscle Preservation

10/28/2025

This week on the Good Medicine Podcast, Dr. David Bearss sits down with Dr. Thomas Gambles to talk about his journey in medicine and the cutting-edge science behind his work in cancer treatment.
Dr. Gambles shares how his experience at Primary Children’s Medical Center, caring for young patients battling cancer, became the driving force behind his career. That experience shaped his purpose — to dedicate his life to improving outcomes for people facing cancer.
Now as the founder of Thera-T, he’s leading efforts to develop next-generation antibody therapies that use artificial intelligence to accelerate discovery and design smarter, more effective drugs. His work represents a new era in precision medicine.

This week on the Good Medicine Podcast, Dr. David Bearss sits down with Dr. Thomas Gambles to talk about his journey in medicine and the cutting-edge science...