12/10/2025
An oldie but a goodie, a study in the Journal of Clinical Psychiatry back in 2015, found that a single course of antibiotics increases the incidence of depression.
Five rounds of antibiotics increases risk of depression to more than 50% (and anxiety, but not psychosis).
I am not recommending to avoid all antibiotics, at all times, but rather to be wise. Not every cough or every discomfort requires antibiotics, but when you visit the urgent care, this is what you are going to be prescribed because - you are visiting a retail clinic.
Your primary care provider builds a relationship with you and they have better follow-up so watch and wait - diligently and wisely -can be better implemented.
A provider who is holistic minded or one in integrative medicine can offer alternatives, when appropriate, that are consistent with the modern scientific literature and backed by traditional medicine practices.