The Journal of Urology

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The Journal of Urology

The official journal of the AUA, The Journal of Urology® is the most widely read and highly cited p

01/16/2026

Testosterone is a critical hormone that impacts various aspects of men's health, and understanding its association with lifestyle factors such as time spent outdoors (TSO) is crucial, especially given increasingly sedentary lifestyles. Analysis of 2205 men revealed that increased TSO is significantly associated with higher serum testosterone levels (b = 9.25 per 1 hour outside daily, P = .007), and a 14% decrease in the odds of low testosterone (odds ratio 0.86, P = .01), independent of several confounding variables.

🔗 Click to read more: https://bit.ly/3LHmPJA

01/15/2026

This study explored the potential of micro-ultrasound-guided biopsy (MB) as a resource-effective alternative to MRI/ultrasound fusion-guided biopsy (PFB) for detecting clinically significant prostate cancer (csPCa). The results showed that MB detected csPCa at higher rates in combined (45% vs. 34%) and systematic biopsies (39% vs. 24%) compared to PFB.

🔗 Click to read more: https://bit.ly/3YGLiBS

01/09/2026

In this study, researchers used imaging mass cytometry and machine learning to map the immune microenvironment of Hunner lesions in IC/BPS. Findings reveal macrophage-rich neighborhoods and distinct immune cell patterns, offering clues to disease mechanisms and future therapies.

🔗 Read more: https://bit.ly/4j7u4qP

01/07/2026

ARTICLE INSIGHTS! Thank you Dr. Rena Malik for your insights into "Perioperative Antimicrobial Strategies in IPP Surgery: Associations Between Antifungals, Oral Antibiotics, and IV Antibiotic Duration, and Infection Outcomes."

🔗 Read the full article: https://bit.ly/48Cm0JD

01/06/2026

In this comment, the authors underscore the significance of this large, high-quality study on active surveillance for small renal masses. With 5-year metastasis rates at just 2% and treatment rates at 21%, these findings confirm AS as a safe option and represent a landmark addition to the literature.

🔗 Read more: https://bit.ly/4j2183r

01/05/2026

In this study, active surveillance for small renal masses (≤4 cm) was shown to be safe, with 5-year rates of local treatment at 21% and metastasis at just 2.3%. These findings support AS as a guideline-backed option for well-selected patients, helping avoid unnecessary interventions while maintaining excellent outcomes.

🔗 Read more: https://bit.ly/4aY917R

01/02/2026

In this study, over half of women delayed seeking care for urinary incontinence—most often due to cost, misconceptions about treatment, and fear. Findings highlight the need for education, telehealth, and outreach to improve access and quality of life.

🔗 Read more: https://bit.ly/45fZHIG

12/30/2025

In this comment, the authors highlight long-term results for NAI plus BCG in BCG-unresponsive papillary NMIBC, showing durable disease-free and progression-free survival and high cystectomy avoidance at 36 months. These findings set an important benchmark for efficacy and reinforce the need for continued long-term reporting.

🔗 Read more: https://bit.ly/491MZ1t

12/29/2025

In this study, NAI (an IL-15 receptor agonist) plus BCG delivered durable outcomes for BCG-unresponsive papillary NMIBC, with 36-month data showing strong disease-free and progression-free survival and high cystectomy avoidance—highlighting a promising chemo-free treatment option.

🔗 Read more: https://bit.ly/4sjAwiC

12/24/2025

In this comment, the authors highlight the potential of semen-based biomarkers (sTWEAK and exomiRs) for prostate cancer diagnosis, prognosis, and active surveillance upgrading. While promising, practical challenges and comparisons with existing tools remain before clinical adoption.

🔗 Read more: https://bit.ly/4j47Buo

12/23/2025

In this study, semen-based biomarkers (sTWEAK and exomiR-221-3p) showed strong accuracy for diagnosing prostate cancer, predicting aggressiveness, and guiding active surveillance decisions—offering a noninvasive path to more personalized care.

🔗 Read more: https://bit.ly/4jahiI8

12/22/2025

ARTICLE INSIGHTS! Thank you Dr. Bogdana Schmidt for the insights on "Neoadjuvant Chemotherapy With Transurethral Resection for Bladder Preservation: 15-Year Follow-Up of the Retained Bladder." Click the link below to read the full article.

🔗 https://bit.ly/4nYebUe

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Linthicum, MD

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