Karen Zaghiyan, MD

Karen Zaghiyan, MD Dr. Zaghiyan is a colore**al surgeon and proctologist in Los Angeles specializing in treatments for Karen Zaghiyan, M.D.

is a surgeon specializing in the surgical and non-surgical treatments for conditions of the colon, re**um, and a**s. Her special interests include women’s colore**al health, inflammatory bowel disease, minimally invasive techniques for the treatment of colore**al diseases and treatment of complex anore**al conditions. Dr. Zaghiyan graduated magna cm laude from University of California, Los Angeles, with a Bachelor of Science degree in Biology. She received her medical degree from University of California, San Diego. She then commenced her general surgery residency at the prestigious Cedars Sinai Medical Center. During her training, she dedicated a year as a clinical research scholar, investigating surgical outcomes in inflammatory bowel disease. One of her studies, which a**lyzed the optimal dosing of perioperative steroids in IBD, has acquired national recognition and changed current practice standards. Dr. Zaghiyan’s academic accomplishments, leadership skills and commitment to educating her fellow peers, earned her the highly respected position as administrative chief resident. After general surgery, she furthered her career ambitions by completing a coveted fellowship in Colon and Re**al Surgery at Cedars Sinai Medical Center that included advanced training in laparoscopic, single incision and robotic techniques. During her training, Dr. Zaghiyan traveled to Singapore, acquiring further training from international leaders in the field of colore**al surgery. Dr. Zaghiyan is board-certified by the American Board of Surgery. Dr. Zaghiyan has lectured both nationally and internationally at various surgical conferences, authored numerous publications in the most prestigious peer-reviewed medical journals, and participates in training surgical residents and fellows at Cedars Sinai Medical Center in Los Angeles. Dr. Zaghiyan’s ongoing dedication to the advancement of her field, in turn, impacts the well being of her patients. With her clinical and research expertise and dedication to providing the highest quality care, Dr. Zaghiyan offers the most advanced and individualized treatments for patients with colon and re**al diseases.

03/12/2026

Any of these surprise you? **alcancer

03/11/2026

Kelley is now well past 5-years with no evidence of disease after re**al cancer diagnosis treatment and low anterior resection. We call this a cure and I’m beyond grateful to have had the opportunity to participate in his care.

A re**al cancer diagnosis is life altering. The surgeon you choose may be one of the most important decisions you make through the journey. As the head of the colore**al tumor board at Cedars Sinai Medical Cebter my team an I are here to make sure you have a multidisciplinary team evaluation and treatment plan tailored for your specific case. If surgery is indicated, i will utilize the most advanced and innovative robotic and Transa**l techniques to preserve sphincter and nerve function to help with postop recovery. Whether you are local in Los Angeles, Orange County, the Inland Empire, Santa Barbara, in San Diego, Northern California or coming from another state, we’re here to make sure you get the best care possible. Don’t hesitate to reach out to our team if you have been diagnosed with colore**al cancer. We’re here to help ☎️310-289-9224. **alcancer **alcancer

03/10/2026

As a surgeon who specializes in IBD and surgery for ulcerative colitis, I am happy to see actually fewer patients needing surgery for their IBD. Invisible multifocal dysplasia in ulcerative colitis is one of the reasons we’re still doing colectomies for UC patients. Patients with PSC are at even higher risk. Often, these patients have had long standing mild inflammation that has caused the precancerous changes. The most common surgery is ileal pouch a**l anastomosis or Jpouch surgery to reduce the risk of recurrent dysplasia or cancer. As always, the decision is based on a risk benefit discussion with the patient. It’s always best to be seen at a high volume IBD center and with a surgeon with expertise doing this complex and often life changing surgery. **alcancer **alsurgeon

Happy International Women’s Day. 💜✨
03/08/2026

Happy International Women’s Day. 💜✨

03/07/2026

Deep infiltrative endometriosis can often involve the colon or re**um. Symptoms may include bleeding, constipation, bloating, diarrhea and are often worse during menstrual cycles. MRI imaging and colonscopy may help with diagnosis. Multidisciplinary team approach is critical for optimal outcomes. **alsurgeon

03/06/2026

Last night, my dear patient Orly sat down with me as we discussed re**al cancer diagnosis, treatment, chemotherapy, low anterior resection, Ileostomy, and life during and after. She shared how she “never said or acted like she was sick”. The full conversation is available to view on IG. I’m so grateful for her gracious bravery in coming on and talking about it. I hope this helps someone. **alcancer **alcancer **alsurgeon

03/05/2026

Never ever ignore these signs. Yes, most of these signs are not gonna lead you to a cancer diagnosis because symptoms of colore**al cancer overlap with every other diagnosis including irritable bowel, sibo, diverticulitis, Crohn’s, colitis, etc! However, ignoring these signs could lead to a missed or delayed diagnosis and worse outcomes. It’s always better to play it safe. Did you have a gut condition or cancer? Please drop you comments below and let me know what your first symptom was! **alcancer **alcancer

03/04/2026

Colon cancer and re**al cancer have
Come colon date reatment algorithms. GO
While colon cancer is generally treated with surgery first. Re**al cancer may be managed by a combination of chemo, radiation, and surgery including sphincter preserving surgery, low anterior resection, intersphincteric and Transa**l TME when necessary to preserve sphincter function.
**alcancer **alcancer

03/03/2026

Dr Karen Zaghiyan is a board certified colore**al surgeon in Los Angeles and affiliated with Cedars Sinai Medical Center. With decades of expertise, compassion and innovative cutting edge approaches she delivers the best care to her patients with colore**al conditions including colon cancer, re**al cancer, ulcerative colitis needing surgery, Crohn’s disease, diverticulitis, hemorrhoids, a**l fistula, a**l fissure, re**al prolapse, and f***l incontinence. She is a leader in colore**al research and innovation always at the forefront of treatments offering robotic, sphincter preserving, and Transa**l approaches as well as office-based non-invasive treatments and laser when appropriate. If you are facing a colore**al condition, reach out to schedule a consultation today. ☎️310-289-9224.
**alcancer

03/03/2026

Dr Karen Zaghiyan is a board certified colore**al surgeon in Los Angeles and affiliated with Cedars Sinai Medical Center. With decades of expertise, compassion and innovative cutting edge approaches she delivers the best care to her patients with colore**al conditions including colon cancer, re**al cancer, ulcerative colitis needing surgery, Crohn’s disease, diverticulitis, hemorrhoids, a**l fistula, a**l fissure, re**al prolapse, and f***l incontinence. She is a leader in colore**al research and innovation always at the forefront of treatments offering robotic, sphincter preserving, and Transa**l approaches as well as office-based non-invasive treatments and laser when appropriate. If you are facing a colore**al condition, reach out to schedule a consultation today. ☎️310-289-9224.
**alcancer #

03/02/2026

Deaths from colore**al cancer are rising and more young people are getting diagnosed. This calls for urgent awareness, research, education, and screening campaigns. I don’t have all the answers, but I’m here to help. We need to fight this together. **alcancer **alcancer **alsurgeon

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90048

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Karen Zaghiyan, MD, FACS, FASCRS is a surgeon specializing in the surgical and non-surgical treatments for conditions of the colon, re**um, and a**s. Her special interests include women’s colore**al health, inflammatory bowel disease, minimally invasive techniques for the treatment of colore**al diseases and treatment of complex anore**al conditions. Dr. Zaghiyan graduated magna cm laude from University of California, Los Angeles, with a Bachelor of Science degree in Biology. She received her medical degree from University of California, San Diego. She then commenced her general surgery residency at the prestigious Cedars Sinai Medical Center. During her training, she dedicated a year as a clinical research scholar, investigating surgical outcomes in inflammatory bowel disease. One of her studies, which a**lyzed the optimal dosing of perioperative steroids in IBD, has acquired national recognition and changed current practice standards. Dr. Zaghiyan’s academic accomplishments, leadership skills and commitment to educating her fellow peers, earned her the highly respected position as administrative chief resident. After general surgery, she furthered her career ambitions by completing a coveted fellowship in Colon and Re**al Surgery at Cedars Sinai Medical Center that included advanced training in laparoscopic, single incision and robotic techniques. During her training, Dr. Zaghiyan traveled to Singapore, acquiring further training from international leaders in the field of colore**al surgery. Dr. Zaghiyan is board-certified by the American Board of Surgery. Dr. Zaghiyan has lectured both nationally and internationally at various surgical conferences, authored numerous publications in the most prestigious peer-reviewed medical journals, and participates in training surgical residents and fellows at Cedars Sinai Medical Center in Los Angeles. Dr. Zaghiyan’s ongoing dedication to the advancement of her field, in turn, impacts the well being of her patients. With her clinical and research expertise and dedication to providing the highest quality care, Dr. Zaghiyan offers the most advanced and individualized treatments for patients with colon and re**al diseases.