11/28/2025
Every Thanksgiving, we hear a lot about the power of gratitude. 🙏
But beyond the warm feelings, there’s fascinating neuroscience behind it.
When I first started exploring longevity medicine, one thing stood out: people who lived longer and aged well often had one thing in common: a deep sense of thankfulness.
Here’s what science shows:
- Gratitude activates dopamine and serotonin, the same neurotransmitters that lift your mood and motivation.
- It lowers cortisol, reducing stress and inflammation that accelerate aging.
- It improves sleep and enhances brain repair overnight.
And over time, gratitude literally rewires neural pathways to focus more on what’s working, not what’s missing.
That’s not just philosophy. It’s neurobiology in action.
This week, as we pause for Thanksgiving, I hope we all reflect on how something as simple as gratitude can be one of the most profound longevity tools we have.