IP-6 Research

07/27/2025

IP-6 Research is advancing an exciting strategic research collaboration with BioLink Therapeutics, INDIA (https://BioLinkTherapeutics.com), aimed at unlocking the full therapeutic potential of IP6 far beyond its traditional role as a dietary supplement. Together, the two organizations are pioneering innovative research programs focused on developing IP6-based medicines. This international partnership combines BioLink’s translational drug development expertise with IP-6 Research Inc.’s deep scientific foundation, paving the way for a new class of therapeutics that could transform the landscape of chronic disease management.

07/10/2025

IP6 improves skin barrier function in an experimental model of Atopic Dermatitis (eczema) thereby potentially being useful as skin cream in this condition: https://onlinelibrary.wiley.com/doi/epdf/10.1111/all.16644

06/07/2025

IP6 in Bone Health

Dietary phytic acid/phytate/myo-inositol hexaphosphate (IP6), a phosphate reservoir in plants, was viewed as antinutrient, caused by an influence on the bioavailability of minerals through its chelating activity. However, there is a growing body of ...

05/28/2025

Further evidence that IP6 can be beneficial in neurodegenerative diseases such as Parkinson’s, Alzheimer’s disease etc.

Myo-inositol-1,2,3,4,5,6-hexakisphosphate (IP6) is commonly found in plant-derived foods and has important pharmacological properties against many pathologies. One of them appears to be neurodegeneration, which is notably stimulated by dysregulated metal metabolism. Consequently, we explore the role...

02/08/2025

Potential benefits of IP6 and its related compounds/enzymes in various neurodegenerative diseases:

Inositol is a vital sugar molecule involved in numerous signaling pathways required for cellular homeostasis and cell survival. Myo-inositol and its phospho-derivatives, inositol phosphates (IPs), are the most prevalent forms of inositol found in living cells. They are involved in regulating ion cha...

02/08/2025

https://a.co/d/e1YFtY7

When Sarah Cripps’ little boy was diagnosed with leukaemia, her reaction was to find out as much as she could as fast as she could, to help her child get well. This book is the result of that work. It is the book she wishes she had found when Teddy was facing chemotherapy. Underpinned by scie...

01/08/2025

IP6 ameliorates ulcerative colitis (UC) in an experimental model.

Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) with an unknown etiology that is currently difficult to treat effectively. Phytic acid, a natural compound found in high-fiber foods, such as grains, has been shown to have many pharmacological functions, such as anti-inflammatory and bl...

10/09/2024

https://www.mdpi.com/journal/biomolecules/special_issues/OE15ZZ10FW

Special Issue in journal Biomolecules: Inositol Phosphates in Health and Disease, 2nd Edition

10/01/2024

For those who are concerned about the safety of InoCell IP6, please read this comprehensive and up-to-date paper:

Dietary phytic acid/phytate/myo-inositol hexaphosphate (IP6), a phosphate reservoir in plants, was viewed as antinutrient, caused by an influence on the bioavailability of minerals through its chelating activity. However, there is a growing body of evidence indicating that IP6 has beneficial (e.g.,....

09/18/2024

Encapsulated IP6 of InoCell enters Breast Cancer cells and induces apoptosis more efficiently "T[t]his work has potential for developing cancer therapeutic applications...that are likely to overcome the severe toxic effects associated with synthetic chemotherapeutic drugs."

Inositol hexakisphosphate (InsP6) is the most abundant inositol polyphosphate both in plant and animal cells. Exogenous InsP6 is known to inhibit cell proliferation and induce apoptosis in cancerous cells. However, cellular entry of exogenous InsP6 is hindered due to the presence of highly negative....

08/17/2024

Hexa-sodium IP6 received "Orphan Drug" designation from FDA

  Palma, Spain and San Diego, USA, February 10, 2021 – Sanifit, a clinical-stage biopharmaceutical company focused on developing treatments for calcification disorders, today announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation (ODD) to its lead compound ...

07/19/2024

Cyclophosphamide (CP) is one of the most used cancer chemotherapeutic drugs. However, it has numerous severe side-effects, not least of which is infertility due to its toxicity in the te**is. Alkhalaf et al show that orally administered IP6 (of InoCell) ameliorates the CP-induced testicular toxicity in rats. “Hence, for cancer patients receiving CP treatments, IP6 can be considered an effective medical treatment for avoiding male infertility.” conclude the authors:

Cyclophosphamide (CP) is commonly used as an anticancer agent but has been associated with high toxicity in several animal organs, including the te**es. Inositol hexaphosphate (IP6) is a polyphosphorylated carbohydrate that is present in foods with high fibre contents and has a wide range of essenti...