Keck Lab

Keck Lab The Keck lab studies the basic mechanisms of DNA replication, recombination and repair.

Research in the Keck lab examines the structural mechanisms that drive DNA replication, replication restart, recombination, and repair reactions. Successful ex*****on of these pathways is essential in all cells, and defects in the proteins that facilitate genome maintenance reactions lead to genome instability, cell death, and disease. Our studies combine structural approaches with biochemical and cell biological methods to answer fundamental structure-function questions in genome biology.

Check out this early holiday gift from our lab friend and collaborator, Kavi Mehta!
12/04/2024

Check out this early holiday gift from our lab friend and collaborator, Kavi Mehta!

Congratulations to Rachel Cueny who received the 2024 Sigrid Leirmo Memorial Award in Biochemistry!
06/18/2024

Congratulations to Rachel Cueny who received the 2024 Sigrid Leirmo Memorial Award in Biochemistry!

Christine Hustmyer (Landick Lab) and Max Rector (Record Lab) were awarded this year's Denton Award. Rachel Cueny (Keck Lab) was awarded this year's Leirmo Award.

Congratulations to Dr. Rachel Cueny! She rocked our second defense in as many weeks! Excellent job!
05/30/2024

Congratulations to Dr. Rachel Cueny! She rocked our second defense in as many weeks! Excellent job!

Congratulations to Dr. Sarah McMillan! A wonderful defense capping off an outstanding five years of scholarship in the ...
05/17/2024

Congratulations to Dr. Sarah McMillan! A wonderful defense capping off an outstanding five years of scholarship in the lab!

We’ve got a couple of (almost) graduates! Sarah defends in one week and Rachel defends in three!
05/10/2024

We’ve got a couple of (almost) graduates! Sarah defends in one week and Rachel defends in three!

Get ready for Sarah's thesis defense on Friday May 17!
05/01/2024

Get ready for Sarah's thesis defense on Friday May 17!

McMillan’s research in the Keck Lab investigated replicative helicase and associated proteins.

As is always the case, this award is the lab’s award. Congratulations and thanks to all Keck Lab members past and prese...
04/18/2024

As is always the case, this award is the lab’s award. Congratulations and thanks to all Keck Lab members past and present!

The honor, presented annually since 1874, recognizes efforts to advance science and society, with the fellows expected to maintain the highest standards of scientific integrity and professional ethics.

04/16/2024

Congratulations to Sarah McMillan whose paper describing how mutations of a helicase loader affect its biochemical function was just published in the Journal of Biological Chemistry!

Ready for commencement to commence!
12/17/2023

Ready for commencement to commence!

It is really neat to see two Keck lab alumni publishing together in their post-Wisconsin lives! Congratulations to Tric...
12/15/2023

It is really neat to see two Keck lab alumni publishing together in their post-Wisconsin lives! Congratulations to Tricia Windgassen and Brian Ferrer!

Immunoglobulin-degrading proteases are secreted by pathogenic bacteria to weaken the host immune response, contributing to immune evasion mechanisms d…

12/14/2023

We are thrilled to welcome Molly Dolan and Zoe Wetmore, both graduate students in the Integrated Program in Biochemistry, to their PhD home in the Keck Lab!

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