
05/19/2025
As an allergist, I never recommend Benadryl.π....
Benadryl (active ingredient: diphenhydramine) is a first-generation antihistamine that crosses the Blood Brain Barrier, causing significant sedation and cognitive effects.
Most are already exhausted due to their allergic symptoms of nasal congestion and stuffiness, itching and sneezing.
Why compound this effect with a first generation antihistamine?
All of our food allergy kiddos and adults receive a food allergy action plan which is a step by step emergency guide for handling food allergic reactions.
After epinephrine administration for a food allergic reaction, one needs to remain alert for proper ongoing medical assessment β not groggy and sedated from outdated medication, so I typically always recommend a non-sedating antihistamine such as (cetirizine, loratidine, fexofenadine) instead of a sedating antihistamine.
The global medical community is already taking action....
Countries like Germany and Sweden have begun restricting access to first-generation antihistamines entirely.
Meanwhile, in the US we have numerous second-generation options (cetirizine, loratadine, fexofenadine) that provide effective symptom relief with minimal side effects.
Consider this and discuss it with your trusted doctor and allergist.