American Society of Pediatric Nephrology

American Society of Pediatric Nephrology The ASPN is an organization of pediatric nephrologists and affiliated health care professionals.

Our primary goals are to promote optimal care for children with kidney disease through advocacy,
education and research; and to disseminate advances in clinical practice and scientific investigation.

Kidney and blood pressure sequelae after pediatric extracorporeal membrane oxygenation: a secondary analysis of the Kidn...
01/26/2026

Kidney and blood pressure sequelae after pediatric extracorporeal membrane oxygenation: a secondary analysis of the Kidney Injury During Membrane Oxygenation pediatric ECMO cohort

Background Acute kidney injury (AKI) is common in children treated with extracorporeal membrane oxygenation (ECMO) and is associated with increased morbidity and mortality. AKI may also increase the risk of long-term chronic kidney disease (CKD) and persistent kidney dysfunction. Hospital discharge....

Corticosteroids augment cyclosporine nephrotoxicity in pediatric nephrotic syndrome: potential role of alternatively act...
01/26/2026

Corticosteroids augment cyclosporine nephrotoxicity in pediatric nephrotic syndrome: potential role of alternatively activated macrophages

Background Cyclosporine A (CsA) is an effective steroid-sparing agent for steroid-dependent nephrotic syndrome (SDNS); however, long-term use can cause chronic kidney injury (CsA nephropathy). We previously reported that alternatively activated macrophages (M2-type) are linked to interstitial fibros...

Case report: Successful treatment of severe, refractory polyomavirus disease with partially HLA-matched donor-derived BK...
01/25/2026

Case report: Successful treatment of severe, refractory polyomavirus disease with partially HLA-matched donor-derived BKPyV-specific T cells in a pediatric kidney recipient

BK polyomavirus–associated nephropathy is a significant therapeutic challenge in kidney transplant recipients, often leading to allograft dysfunction. We report on a 12-year-old male kidney transplant recipient with severe, biopsy-proven BK polyomavirus–associated nephropathy and concurrent JC p...

Review: Proteinuria in adolescence
01/25/2026

Review: Proteinuria in adolescence

Proteinuria is a common laboratory finding in adolescents. It is often benign and due to transient causes or orthostatic proteinuria. However, it can also be an early sign of underlying conditions that may lead to long-term kidney damage. Early recognition and appropriate diagnostic evaluation are c...

Hospitalization burden in children on dialysis: insights from the Italian Registry of Pediatric Chronic Dialysis (IRPCD)...
01/25/2026

Hospitalization burden in children on dialysis: insights from the Italian Registry of Pediatric Chronic Dialysis (IRPCD)

Background Children receiving kidney replacement therapy frequently face complications resulting in recurrent hospitalizations. This nationwide retrospective observational study, conducted using data from the Italian Registry of Pediatric Chronic Dialysis (IRPCD), aimed to compare hospitalization ra...

Neuraminidase activity in pediatric nephrotic syndrome
01/24/2026

Neuraminidase activity in pediatric nephrotic syndrome

Home Pediatric Nephrology Article Neuraminidase activity in pediatric nephrotic syndrome Research Letter Open access Published: 17 January 2026 (2026) Cite this article You have full access to this open access article Download PDF Save article View saved research Pediatric Nephrology Aims and scope....

Exergaming as a promising approach to promote physical activity in children and adolescents during hemodialysis?
01/24/2026

Exergaming as a promising approach to promote physical activity in children and adolescents during hemodialysis?

Home Pediatric Nephrology Article Exergaming as a promising approach to promote physical activity in children and adolescents during hemodialysis? Research Letter Open access Published: 15 January 2026 (2026) Cite this article You have full access to this open access article Download PDF Save articl...

Oral liposomal iron vs. oral iron polymaltose in children with chronic kidney disease iron deficiency anemia: a cross-ov...
01/24/2026

Oral liposomal iron vs. oral iron polymaltose in children with chronic kidney disease iron deficiency anemia: a cross-over study

Background Limited data exist on the use of novel iron therapies in children with chronic kidney disease (CKD). We conducted a cross-over study to compare iron polymaltose complex (IPC) and liposomal iron in pediatric patients with CKD and iron deficiency anemia (IDA). Methods Cross-over study of 33...

Hyperkalemia in pediatric nephrectomy: a common complication
01/23/2026

Hyperkalemia in pediatric nephrectomy: a common complication

Background Hyperkalemia following nephrectomies in children is a poorly studied, potentially life-threatening complication. We describe the frequency and risk factors for hyperkalemia in pediatric patients who underwent nephrectomies resulting in an anephric state. Methods This was a single center r...

APOL1 kidney risk variants and outcomes in children with congenital anomalies of the kidney and urinary tract
01/23/2026

APOL1 kidney risk variants and outcomes in children with congenital anomalies of the kidney and urinary tract

Background APOL1 high-risk variants predispose to chronic kidney disease (CKD) in individuals of African genetic ancestry due to podocyte toxicity. As congenital anomalies of the kidney and urinary tract (CAKUT) have variable outcomes potentially driven by podocyte injury, we hypothesize that the ou...

N-terminal pro B-type natriuretic peptide levels in a paediatric haemodialysis cohort
01/23/2026

N-terminal pro B-type natriuretic peptide levels in a paediatric haemodialysis cohort

Background Accurate volume assessment is essential in the management of children on dialysis as excess volume is a key cause of arterial hypertension and is associated with the development of hypertension-mediated organ injury. Our objective was to describe NT-proBNP concentrations in a cohort of ch...

Dialysis modality and mortality of the Contemporary Infant and Neonatal Dialysis (COINED) Cohort: a Pediatric Nephrology...
01/23/2026

Dialysis modality and mortality of the Contemporary Infant and Neonatal Dialysis (COINED) Cohort: a Pediatric Nephrology Research Consortium (PNRC) study

Background Recent technologic advances in neonatal dialysis have changed current dialysis practices. The goal of this study was to define demographics, diagnoses, initial dialysis modality, modality changes, and outcomes of neonates receiving dialysis. Methods Retrospective, multicenter cohort of ne...

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