12/15/2025
✨Take a look at this stunning confocal image of a mouse duodenum intestinal organoid!
⚪White: Cell nuclei stained with DAPI
🟡Yellow: Filamentous actin (cytoskeleton) marked by phalloidin
🟣Purple: Mucin 2, a major gel-forming mucin from goblet cells, detected using a MUC2-specific antibody and Alexa Fluor™ 594
This organoid was grown in Matrigel, fixed after the first passage, and captured using the Nikon AX/R confocal microscope. Notice the vibrant mucin signal in goblet cells and the organoid lumen—shedding light on intestinal epithelial biology!
🔬 Research by Katarina Tokarcikova (https://bit.ly/4rGoBLr), Ales Pavlik (https://bit.ly/48ZxB6T), Lubomira Gresakova, and Petr Slama
📍 Mendel University in Brno, Czech Republic
📍 Centre of Biosciences SAS, Košice, Slovak Republic
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Ústav morfologie, fyziologie a genetiky zvířat