04/05/2020
Acupuncture Improves Neural Function in Middle Cerebral Artery Stroke Study
Chinese Medicine, including acupuncture, herbal medicine, and tuina is widely used as a complementary and even primary treatment for stroke. Particular attention has been paid to stroke recovery for which acupuncture shows particularly positive results.
Recently, researchers from the Acupuncture and Moxibustion and Tuina College at Tianjin University of Traditional Chinese Medicine in Tianjin China conducted a rat model study to explore the beneficial effects of acupuncture on stroke recovery. Middle cerebral artery occlusion in rat models is a widely used method to study stroke affects and recovery. In
OBJECTIVES:
To observe recovery in movement function in rats with middle cerebral artery occlusion (MCAO) after acupuncture treatment.
METHODS:
According to the randomized and controlled principle 1384 rats were divided into the basic control group (including the normal, sham, model control, model without intervention, Nimodipine, and para-Renzhong groups) and the acupuncture group (including the Neiguan (PC 6), Weizhong (BL 40), Sanyinjiao (SP 6), Chize (LU 5), Renzhong (GV 6) and non-acupoint groups). MCAO was modeled by Zea-longa's thread ligation and rats with scores of 1-3, as assessed by Zausinger's six-point method, were used in this study. Moreover, in the acupuncture group each acupoint was set with 12 different parameters by the orthogonal intersection method, resulting in 78 groups with 18 rats per group. The rats were treated by acupuncture once every 12 h for a total of six sessions and neurobehavioral scores were measured after each session. The neurobehavioral scores were compared by one-way ANOVA using the statistical software SPSS 17.0.
RESULTS:
After acupuncture therapy the mean neurobehavioral scores in MCAO rats increased gradually at each time point with a significant difference among the six scores, but with no significant differences between the fourth (48 h) and the fifth score (60 h), and between the fifth (60 h) and the sixth (72 h) score (P > 0.05).
CONCLUSIONS:
MCAO rats gradually recovered movement function over multiple acupuncture sessions. After the forth acupuncture session (48 h), the neurobehavioral scores of rats with cerebral infarction remained stable. Acupuncture treatment had a reliable curative effect on movement function in cerebral infarction rats.
Researchers used 1384 rats divided into various sham, control, western medicine (nimotop, nimodipine) and acupuncture treatment groups.
Points used within the acupuncture treatment group were as follows:
PC6, UB40 , SP6 , LU5, GV6
The acupuncture group received treatment once every 12 hours for 3 days (6 sessions total) and neurobehavioral scores were measured after each session.
Researchers found significant improvements in neurobehavioral scores within the acupuncture group with a stabilization of effects at 48h (after the 4th session). Researchers concluded that acupuncture treatment "had a reliable curative effect on movement function in cerebral infarction rats."