Global Regenerative Group

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Global Regenerative Group

Global Regenerative Group invests, identifies, develops and markets groundbreaking medical technologies related to Regenerative Medicine, globally!

Global OrthoBiologic is a privately-held groundbreaking medical technologies’ company for use in therapies that significantly enhance the body’s natural healing ability. The company has developed extensive experience in the most advanced medical device industries. In the past several years, the emphasis has been focused exclusively on Regenerative Medicine and stem cell technologies, products, and

therapies. The technologies for stem cells are cutting edge, safe, clean and do not use any additives, enzymes, or require culturing or growing of cells. Global OrthoBiologic consults with medical technology companies that are startups and/or companies looking to expand and grow their business. Global OrthoBiologic has built a comprehensive network of experts in Europe, South America, Middle East, Asia, and Australia. The company partners with recognized medical facilities worldwide for evidence-based clinical medicine. Global OrthoBiologic subsidiary Global ACADEMY, therefore, provides educational events allowing physicians and healthcare practitioners to expand their knowledge of best practices and clinical applications of regenerative medicine in stem cell and gene therapy, novel biotechnologies, and tissue engineering. Global ACADEMY provides training workshops consisting of lectures and hands-on practicum to mentor physicians and healthcare professionals in best practices and standardized methods for optimal results and better patient outcomes. Additionally, larger, international conferences are provided in various locations to provide opportunities for physicians to learn new information and relevant protocols that impact their work while creating an occasion for networking with highly respected and esteemed international thought leaders with clinical experience in a variety of specialties. Educational information is provided to physicians both at sponsored events as well as through Global ACADEMY’s digital websites, physician portal, newsletters, email content, and social media. Membership in Global ACADEMY is available for healthcare professionals interested in up-to-date information about novel therapies, innovative technology, specialized protocols and best clinical translation practices. Global OrthoBiologic holds exclusive distribution rights for various medical devices, topical skin care products, food supplements, biotechnologies and gene therapies in the International markets OUS, as well as other jurisdictions, with a steady stream of products in the pipeline through our Global Life subsidiary and Global partners. Global OrthoBiologic’s current focus is in Europe, Middle East and Asia; however, Global OrthoBiologic is quickly expanding its reach through collaborations with international companies and academic institutes. Global OrthoBiologic, therefore, is cognizant of the regulatory status of various countries and seeks to spotlight various regulatory governments open to regenerative medicine. Global LIFE is a subsidiary involved in regenerative medicine research for auto-immune disorders, chronic pain, injuries, Alzheimer’s disease and cancer. These goals require Global LIFE to search for funding in order to maintain these programs and provide better patient options and outcomes for difficult diseases. Finally, Global ACADEMY provides access for its membership and those within the healthcare industry to participate in events focused on diseases due to aging. Using various anti-aging strategies, Global ACADEMY collaborates with educational institutes, regenerative medicine companies and governmental bodies to globally impact patients through anti-aging medicine Regenerative Medicine, allowing them to live a better quality of life as they advance in years. What separates Global OrthoBiologic from the competition? Other companies would believe that once a distributor is selected, the job is done. However, Global OrthoBiologic knows that the job has only just begun. Once the selection process is completed, the company ensures that all the necessary support is provided to our exclusive distributor for success in the host market.

27/07/2025

💉 liposmart® is a sterile, single-use Class IIa medical device designed for efficient purification and processing of small volumes of lipoaspirate. Using gentle micro-fragmentation and washing, the procedure is quick, safe, and performed entirely at the point of care —whether in a clinic or surgical suite.

🧬 Unlike conventional systems, liposmart® preserves the stromal vascular niche, maintaining the full regenerative potential of the adipose tissue—without enzymes, chemicals, or centrifugation. Its dual-stage filtration system (1200μm and 700μm) ensures consistent tissue sizing, enhancing nutrient exchange and integration with recipient tissues 🔄.

Thanks to its refined texture, the final product can be easily reinjected through 21G to 27G needles, allowing for precise and even distribution. The complete kit includes everything needed for harvesting, processing, and reinjection—ideal for orthopedic and regenerative applications.

25/07/2025

🧬 Understanding Exosomes – Nature’s Healing Packages

Exosomes are microscopic messengers packed with powerful healing instructions. So what’s inside these natural delivery systems? Let’s break it down:

1️⃣ Proteins – including regenerative growth factors:
🔹 PDGF – Signals cells to multiply and repair
🔹 VEGF – Stimulates new blood vessel formation
🔹 TGF-β – Calms inflammation and aids in tissue repair

2️⃣ Genetic Instructions (RNA):
∙ Turn healing genes ON
∙ Switch inflammatory genes OFF
∙ Guide stem cells to become specific tissues

3️⃣ Lipids – the delivery support team:
∙Protect the cargo during transport
∙Help exosomes fuse with target cells
∙Ensure precise delivery where healing is needed

These natural nano-carriers are redefining regenerative medicine—targeted, intelligent, and 100% your own.

25/07/2025

liposmart® is a CE Class IIa medical device engineered to process adipose tissue into a clinically valuable, cell-rich fraction—UFAT (Unfiltered Fat-derived Autologous Tissue).

Using patented elastomeric pump technology and dual-stage filtration, liposmart® preserves the full therapeutic profile of adipose tissue, including stem cells, growth factors, and the structural cellular matrix—without enzymes, chemicals, or centrifugation.

Key Advantages:
• >95% regenerative cell preservation
• No enzymatic digestion or additives
• 20-minute point-of-care protocol
• Consistent, reproducible output
• CE Mark Class IIa certified for professional use

Technical Specifications:
🔹 Processing Volume: Up to 120ml adipose tissue
🔹 Output Volume: 80–100ml UFAT
🔹 Cell Viability: >95%
🔹 Filtration: 1200μm / 700μm
🔹 Needle Compatibility: 21G–27G
🔹 Shelf Life: 2 years | Sterile | Room temp storage

Designed for precision. Built for clinical efficiency. liposmart® enables a new standard in autologous regenerative therapies.

25/07/2025

🇰🇷exosmart™️ Successfully Registered in South Korea 🇰🇷

We are pleased to announce that exosmart™️ has received regulatory approval from the Korean Ministry of Food and Drug Safety (MFDS), allowing us to enter one of Asia’s most advanced healthcare markets.

A Significant Achievement: The Korean medical device registration process is recognized as one of the most stringent globally. Meeting MFDS requirements demanded months of meticulous preparation, comprehensive documentation, and close collaboration with regulatory experts. This approval confirms that exosmart™️ meets the highest international standards for safety and efficacy.

Bringing Innovation to an Innovative Market: South Korea has long been a global leader in medical technology, particularly in regenerative medicine and aesthetic procedures. We are honored to introduce exosmart™️ to Korean healthcare professionals, offering them a new tool that enhances their existing PRP protocols.

For a European medical technology to gain acceptance in Korea—a country known for pioneering medical innovations—represents a significant validation of our technology and approach.

Benefits for Korean Healthcare Providers

exosmart™️ enables Korean clinicians to:
•⁠ ⁠Transform standard PRP into concentrated exosome therapy
•⁠ ⁠Achieve particle concentrations up to 3.0 × 10¹³ per mL
•⁠ ⁠Process treatments in under 30 minutes at point of care
•⁠ ⁠Maintain 100% autologous safety profile
•⁠ ⁠Apply across multiple specialties: orthopedics, dermatology, aesthetic medicine, and more

The technology integrates seamlessly with existing PRP workflows, requiring only an additional 5 minutes to concentrate the therapeutic components typically discarded during standard processing.

Acknowledgments: This achievement reflects the dedication of our regulatory affairs team, who navigated the complex approval process with expertise and persistence. We also thank our Korean partners for their invaluable guidance in understanding local requirements and expectations.

Moving Forward in Korea: With registration complete, we are implementing a comprehensive market entry strategy:
•⁠ ⁠Establishing distribution networks across major Korean cities
•⁠ ⁠Developing Korean-language training materials and protocols
•⁠ ⁠Organizing educational symposiums for healthcare professionals
•⁠ ⁠Building partnerships with leading medical institutions

We look forward to collaborating with Korean medical professionals and learning from their extensive experience in regenerative medicine.

Contact Information: Korean healthcare providers interested in incorporating exosmart™️ into their practice are invited to contact our authorized distributor for detailed information about availability and training opportunities.

exosmart™️ is now available in South Korea through exclusive authorized distribution partner.

23/07/2025

The Stromal Vascular Niche in Adipose Tissue: A Functional Regenerative System 🧬

Adipose tissue is not merely an energy reserve. Within it lies a complex microenvironment known as the stromal vascular niche (SVN) — a critical component in tissue repair and regeneration.

Key structural and functional features:
• Mesenchymal stem cells in direct interaction with their native microenvironment
• Vascular structures with preserved lumens 🩸
• Capillaries embedded between adipocytes
• A naturally regulated release of regenerative signaling molecules 🔄

Conventional processing methods often disrupt this architecture, limiting the clinical potential of adipose-derived cells. liposmart® is designed to preserve the stromal vascular niche without enzymatic digestion or centrifugation, maintaining the full integrity of its regenerative components.

Clinical relevance:
Preserving the native microenvironment allows for the targeted, time-sensitive release of regenerative factors. This supports improved outcomes in various applications — from aesthetic procedures to the management of degenerative joint conditions.

23/07/2025

💉 Transform PRP into powerful exosome therapy with exosmart™ — a CE-MDR certified Class IIa medical device that concentrates your patient’s own healing potential into a highly potent, autologous therapeutic solution.

⏱️ In just 30 minutes, exosmart™ isolates and concentrates up to 30 trillion exosomes per milliliter — 136× the reference standard — while preserving all critical components, including exosomes (30–150nm), growth factors (VEGF, TGF-β, FGF), cytokines, plasma proteins, and up to 95% of platelets.

🔬 Validated under MISEV2023 standards, exosmart™ delivers 93.2% CD9-positive purity and a 47% increase in PDGF-bb growth factor.

🩺 From orthopedics to aesthetics, surgical recovery to wound care, exosmart™ delivers standardized, autologous therapy with zero rejection risk, no adverse events, and a 100% processing success rate.

This is precision regenerative medicine — standardized, elevated, and entirely yours. This is exosmart™.

21/07/2025

✨ Transform Your Practice with Scientific Excellence ✨

🧬 30 trillion exosomes/mL
🚀 136× reference concentration
🩸 100% autologous = zero rejection risk
⏱️ 20-minute total processing
✅ MISEV2023 compliant
🇪🇺 CE-MDR certified medical device

exosmart™ turns your PRP into power-packed exosome therapy—preserving every healing molecule while removing only water and salts. Release 5× concentrated exosomes, growth factors, and proteins—purely yours, exceptionally potent.

20/07/2025

Traditional adipose stem cell processing requires enzymatic digestion and complex lab expansion - but strict regulations make clinical use challenging. It's time for a breakthrough ✨

Enter liposmart® - Revolutionary UFAT Technology 🌟

We've created the world's first Unified Fat Tissue (UFAT) derivative - recapturing ALL the biophysical properties of your original fat tissue in one revolutionary product 💯🧬

Why UFAT changes everything:
✅ Mechanical processing only - no enzymes needed
✅ Minimal manipulation = regulatory compliance
✅ Preserves complete stromal vascular niche
✅ Maintains natural regenerative fullness
✅ Ready for immediate clinical use

Your own adipose tissue, in its regenerative fullness. | The future of fat grafting is unified, personalized, and powerful 🚀

18/07/2025

🩸 FROM BLOOD DRAW TO BREAKTHROUGH The exosmart™ 3-Step Revolution

STEP 1: COLLECTION - ⏱️ 2 minutes
Draw 60mL blood using standard anticoagulant tubes → Same as routine blood test

STEP 2: SEPARATION - ⏱️ 5-20 minutes
Centrifuge separates components → Red cells sink, plasma rises → Result: 25-30mL plasma ready for processing

STEP 3: CONCENTRATION - ⏱️ 3-5 minutes
exosmart™ ultrafiltration magic happens → Water and salts pass through membrane → Exosomes, platelets, growth factors concentrated → Result: 6-7mL therapeutic powerhouse

⏰ TOTAL TIME: 15-30 MINUTES | 🎯 RESULT: CONCENTRATED HEALING
Transform routine procedures into advanced regenerative therapy with the body's own healing messengers.

18/07/2025

liposmart® - Precision Engineering Meets Regenerative Science 🧬✨

Use the full regenerative potential of human adipose tissue through sophisticated processing technology designed to preserve nature's healing blueprint 🔬💫

Advanced Micro & Nano Fragmentation: 🎯 Progressive size reduction using dual filtration (1,200μm + 700μm) removes fibrous tissue while preserving beneficial regenerative elements and natural fat architecture

Scientific Washing Protocol: 🧪 Physiological solution cleansing eliminates blood, cellular debris, and pro-inflammatory contaminants without compromising therapeutic components

Cell Stress Protection: 🛡️ Constant fluidic immersion during processing minimizes mechanical trauma, preserving the stromal vascular niche and protecting mesenchymal stem cells and pericytes

Precision Volume Control: 📏 Integrated reference scale provides real-time monitoring of liquid and tissue volumes throughout processing for consistent, measurable results

Zero Waste Technology: ♻️ Double withdrawal access system captures regenerative cells and cytokines from wash fluid - nothing valuable is lost in the process

The result: Optimally processed adipose tissue that maintains maximum regenerative capacity while achieving ideal consistency for therapeutic application

Where science meets surgical precision 🔬⚕️

16/07/2025

Transform your PRP into advanced exosome therapy with exosmart™—the revolutionary CE-MDR certified medical device that concentrates your body’s own healing power.

⚡ PROCESSING POWER:
▪ 30mL plasma → 6-7mL concentrated therapeutic product
▪ 5x concentrated autologous exosomes
▪ 136x higher than reference standards
▪ 100% processing success rate

🎯 TECHNICAL SPECIFICATIONS:
▪ CE-MDR certified Class IIa medical device
▪ 15 kDa molecular weight cutoff membrane
▪ Patented ultrafiltration technology
▪ MISEV2023-compliant validation

🏆 CLINICAL ADVANTAGE: Achieve in ONE session what traditional approaches require multiple treatments. From orthopedics to aesthetics—standardized, reproducible results every time.

16/07/2025

🚀 Meet liposmart® boost 60 ml — the future of fat processing is here! 🔬

Precision-engineered to refine, purify, and reinject your own adipose tissue with unmatched accuracy, liposmart® boost uses the power of natural regeneration and rejuvenation.

Perfect for orthopedic, aesthetic, and regenerative therapies, this next-gen technology works right at the point of care — minimally invasive, biologically intelligent, and incredibly effective.

Step into tomorrow’s treatment today with liposmart® boost.

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http://globalregenerative.group/

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