Global Regenerative Group

Global Regenerative Group Global Regenerative Group invests, identifies, develops and markets groundbreaking medical technologies related to Regenerative Medicine, globally!

Global OrthoBiologic is a privately-held groundbreaking medical technologies’ company for use in therapies that significantly enhance the body’s natural healing ability. The company has developed extensive experience in the most advanced medical device industries. In the past several years, the emphasis has been focused exclusively on Regenerative Medicine and stem cell technologies, products, and therapies. The technologies for stem cells are cutting edge, safe, clean and do not use any additives, enzymes, or require culturing or growing of cells. Global OrthoBiologic consults with medical technology companies that are startups and/or companies looking to expand and grow their business. Global OrthoBiologic has built a comprehensive network of experts in Europe, South America, Middle East, Asia, and Australia. The company partners with recognized medical facilities worldwide for evidence-based clinical medicine. Global OrthoBiologic subsidiary Global ACADEMY, therefore, provides educational events allowing physicians and healthcare practitioners to expand their knowledge of best practices and clinical applications of regenerative medicine in stem cell and gene therapy, novel biotechnologies, and tissue engineering. Global ACADEMY provides training workshops consisting of lectures and hands-on practicum to mentor physicians and healthcare professionals in best practices and standardized methods for optimal results and better patient outcomes. Additionally, larger, international conferences are provided in various locations to provide opportunities for physicians to learn new information and relevant protocols that impact their work while creating an occasion for networking with highly respected and esteemed international thought leaders with clinical experience in a variety of specialties. Educational information is provided to physicians both at sponsored events as well as through Global ACADEMY’s digital websites, physician portal, newsletters, email content, and social media. Membership in Global ACADEMY is available for healthcare professionals interested in up-to-date information about novel therapies, innovative technology, specialized protocols and best clinical translation practices. Global OrthoBiologic holds exclusive distribution rights for various medical devices, topical skin care products, food supplements, biotechnologies and gene therapies in the International markets OUS, as well as other jurisdictions, with a steady stream of products in the pipeline through our Global Life subsidiary and Global partners. Global OrthoBiologic’s current focus is in Europe, Middle East and Asia; however, Global OrthoBiologic is quickly expanding its reach through collaborations with international companies and academic institutes. Global OrthoBiologic, therefore, is cognizant of the regulatory status of various countries and seeks to spotlight various regulatory governments open to regenerative medicine. Global LIFE is a subsidiary involved in regenerative medicine research for auto-immune disorders, chronic pain, injuries, Alzheimer’s disease and cancer. These goals require Global LIFE to search for funding in order to maintain these programs and provide better patient options and outcomes for difficult diseases. Finally, Global ACADEMY provides access for its membership and those within the healthcare industry to participate in events focused on diseases due to aging. Using various anti-aging strategies, Global ACADEMY collaborates with educational institutes, regenerative medicine companies and governmental bodies to globally impact patients through anti-aging medicine Regenerative Medicine, allowing them to live a better quality of life as they advance in years. What separates Global OrthoBiologic from the competition? Other companies would believe that once a distributor is selected, the job is done. However, Global OrthoBiologic knows that the job has only just begun. Once the selection process is completed, the company ensures that all the necessary support is provided to our exclusive distributor for success in the host market.

liposmart® offers a standardized, enzyme-free, non-centrifuged approach to adipose tissue processing. The system preserv...
12/14/2025

liposmart® offers a standardized, enzyme-free, non-centrifuged approach to adipose tissue processing. The system preserves the intrinsic vascular stromal network, including slit-lumen capillaries, stromal stem cells, and preadipocytes, producing a structurally intact, clinically ready product.

💡 Clinical Mechanism
Following micro-injury or degeneration, pericytes within the preserved microvascular matrix transition into MSC-like reparative cells. These cells release targeted chemokines and cytokines supporting:

✔️ Controlled angiogenesis
✔️ Reduction of fibrosis
✔️ Enhanced cellular viability
✔️ Local immune modulation

Immunohistochemical evaluation demonstrates abundant MSCs and pericytes throughout the liposmart® stromal matrix, confirming the integrity and therapeutic value of the processed tissue.

Science meets simplicity. The exosmart™ Skin Protocol. ✨Our streamlined 4-step method transforms your own blood into a p...
12/11/2025

Science meets simplicity. The exosmart™ Skin Protocol. ✨

Our streamlined 4-step method transforms your own blood into a potent autologous regenerative solution for skin rejuvenation - safe, precise, and clinic-ready.
🩸 STEP 1: Prepare PRP + PPP
💉 STEP 2: Load exosmart™
⚡ STEP 3: Activate
🌟 STEP 4: Ready for application

The final activated exosomes can support a wide range of dermatologic goals, including skin regeneration, skin boosters, texture refinement, and overall rejuvenation.

Swipe to explore the full process ➡️

exosmart™: A safe and precise autologous regenerative solution for skin health.

Adipose-Derived Exosomes: Small Messengers, Big Regenerative Potential ✨Adipose tissue is one of the body’s most abundan...
12/10/2025

Adipose-Derived Exosomes: Small Messengers, Big Regenerative Potential ✨

Adipose tissue is one of the body’s most abundant sources of regenerative exosomes. These tiny vesicles carry proteins and signaling molecules that help guide inflammation, metabolism, and tissue repair. No surprise they’ve become a major focus in regenerative science.

Why They’re Studied 🔬
• Support natural tissue repair and wound healing
• Play a role in metabolic regulation
• Influence immune responses linked to inflammatory and autoimmune conditions

The Catch ⚠️
Getting adipose exosomes requires liposuction - an invasive procedure followed by complex lab processing that can take weeks. That makes point-of-care treatment nearly impossible.

A Practical Alternative for Clinics 💡
The exosmart™ system avoids surgical harvesting by using a simple blood draw. The full plasma sample is processed to capture a broad range of natural healing factors, producing a complete autologous therapy in about 30 minutes—all within the clinic.

Adipose exosomes are powerful, but not practical for routine care. exosmart™ delivers a safe, efficient, same-visit solution shaped for modern regenerative practice.

liposmart® Concept - Where Precision Meets Regeneration 🧬liposmart® refines human adipose tissue into a highly regenerat...
12/10/2025

liposmart® Concept - Where Precision Meets Regeneration 🧬

liposmart® refines human adipose tissue into a highly regenerative product while preserving the tissue’s intrinsic healing potential.

▪️ Micro & Nano Fragmentation
Reduces tissue particle size without disrupting regenerative components.
▪️ Gentle Washing
Removes blood and impurities while protecting therapeutic elements.
▪️ Cell Protection
Maintains the stromal vascular niche, preserving stem cells, pericytes, and supportive structures.
▪️ Precision Control
Regulates tissue and fluid volumes for stable, reproducible outcomes.
▪️ Zero Waste
Recovers valuable regenerative cells and signaling factors from the wash fluid.

The outcome is adipose tissue optimized for regenerative use - highly effective, biologically rich, and delivered in a consistent, treatment-ready form.

exosmart™ - A scientifically grounded solution for stronger, denser hairexosmart™ uses advanced ultrafiltration technolo...
12/08/2025

exosmart™ - A scientifically grounded solution for stronger, denser hair

exosmart™ uses advanced ultrafiltration technology to concentrate autologous exosomes and growth factors, providing a personalized therapy for hair restoration. 🧬

▪ Particle concentration: up to 3.0 × 10¹³ particles/ml
▪ Marker expression: CD9 (93.2%), CD63 (90.1%), CD81 (69.0%)
▪ Growth factors: PDGF-bb +47%
▪ Safety: No serious adverse reactions

exosmart™ is a safe, effective, and scientifically proven solution for stronger, fuller, and healthier hair. 💡

Images provided by Cànons Clinics

liposmart® - an innovative Class IIa medical device designed to provide a sterile, single-use, closed system for safely ...
12/07/2025

liposmart® - an innovative Class IIa medical device designed to provide a sterile, single-use, closed system for safely harvesting and processing fat grafts. Engineered for versatility, it supports a wide range of regenerative and aesthetic applications with precision and consistency.

🧪 Why liposmart®?

✅ Purification & Micro-sizing
Converts lipoaspirate into highly bioavailable tissue suitable for infiltrative use in injured, aging, or degenerative areas.
✅ Preservation of the Stromal Vascular Niche
Advanced filtering and washing protect the native architecture of adipose tissue, enhancing cellular responsiveness and regenerative potential.
✅ No Enzymes. No Centrifuge. No Guesswork.
Processed through gentle mechanical refinement in a single surgical stage—whether in-clinic or in an OR.
✅ Minimally Invasive, Maximally Effective
A smart, surgeon-friendly solution engineered to support restoration within the micro-environment of damaged tissues.

Why it works: liposmart® UFAT 60 ml BOOST 💉✨This system taps into the body’s natural regenerative potential by preservin...
12/05/2025

Why it works: liposmart® UFAT 60 ml BOOST 💉✨

This system taps into the body’s natural regenerative potential by preserving the integrity of adipose tissue, avoiding the disruption and inconsistency often seen with traditional fat grafting.

🔹 Preserves the Vascular Stromal Niche
Maintains adipose-derived cells, vascular elements, and native matrix essential for sustained regeneration.
🔹 Gentle Mechanical Processing
Creates a clean, uniform injectate in a closed, sterile environment - no enzymes, no thermal or chemical damage.
🔹 Retains Native Extracellular Matrix
Keeps collagen and structural scaffold intact, supporting growth factors and seamless tissue integration.
🔹 Delivers visible, durable outcomes
Enhances skin, hair, and texture within weeks, with results that typically last 12 months or more.

Regeneration. Precision. Results.
📩 Interested in distribution or partnership opportunities? Reach out to us directly.

✨ Platelet-Derived Exosomes: The Heart of Autologous Therapy ✨Platelets are key players in tissue repair, releasing grow...
12/03/2025

✨ Platelet-Derived Exosomes: The Heart of Autologous Therapy ✨

Platelets are key players in tissue repair, releasing growth factors and exosomes that trigger healing. But standard PRP methods often fall short:

❌ Inconsistent results – Platelet concentrations vary by patient, protocol, and equipment.
❌ Wasted potential – Most methods discard platelet-poor plasma (PPP), losing billions of exosomes and growth factors.

exosmart™ changes the game:
✅ Total Plasma Processing – Captures all regenerative components from both platelet-rich and platelet-poor plasma.
✅ High Potency – Concentrated platelets + exosomes + full spectrum of plasma growth factors.
✅ Standardized & Predictable – Automated system delivers a consistent, high-quality therapeutic dose every time.
✅ Validated Excellence – Up to 3.0 x 10¹³ particles/mL, >90% exosome purity, meets MISEV2023 guidelines.

The future of regenerative medicine isn’t just platelets—it’s the complete healing profile of a patient’s blood. That’s the power of exosmart™.

✨ liposmart® brings a new standard to regenerative care ✨Instead of relying on complex machines or harsh processing meth...
12/03/2025

✨ liposmart® brings a new standard to regenerative care ✨

Instead of relying on complex machines or harsh processing methods, liposmart® streamlines fat grafting into a clean, efficient, single-step process. The tissue stays protected, the structure stays intact, and the body receives material it recognizes as its own.

Fat is gently harvested, refined, and prepared in a closed, sterile system - ready to support natural repair and regeneration. The approach is minimally invasive, making recovery easier for patients and workflow smoother for practitioners. Whether used in-office or in a surgical suite, the system is engineered for consistency, safety, and clinical confidence.

Technology that respects biology. Healing that starts from within.
📱 To learn more or bring liposmart® into your practice, contact us for details. 📱

✨ A Smarter Choice: exosmart™ ✨💡 What it is: exosmart™ is a plasma separated from human blood through ultrafiltration.Th...
12/01/2025

✨ A Smarter Choice: exosmart™ ✨

💡 What it is: exosmart™ is a plasma separated from human blood through ultrafiltration.
This is a medical device that activates high concentrations of platelet-derived components to induce tissue repair.

⚡ How it works: Ultrafiltration mechanically stimulates platelets to release exosomes, boosting purity and concentration for more effective regenerative results.

🌱 Why exosomes over PRP:
▪ Superior stability & lower immunogenicity
▪ Enhanced intercellular signaling
▪ More precise tissue regeneration
▪ Key mediators of PRP’s physiological effects

Experience the next level of personalized regenerative therapy with exosmart™.

liposmart® sets a new standard in adipose tissue processing - a cutting-edge F.A.T. (Fluid Adipose Tissue) system defini...
11/30/2025

liposmart® sets a new standard in adipose tissue processing - a cutting-edge F.A.T. (Fluid Adipose Tissue) system defining the next era of regenerative medicine with Unified F.A.T. Tissue (UFAT). 💉

As a Class IIa medical device, it’s engineered to harvest, process, purify, and reinject autologous adipose tissue with remarkable precision and efficiency.
A refined approach for clinicians ready to elevate their practice with advanced, science-driven regeneration. 🚀🔬

✨ Exosomes: Tiny Messengers, Big Impact These nanoscale vesicles (30–150 nm) are the powerhouses of regenerative medicin...
11/27/2025

✨ Exosomes: Tiny Messengers, Big Impact

These nanoscale vesicles (30–150 nm) are the powerhouses of regenerative medicine. They deliver growth factors, cytokines, and genetic instructions to:

💉 Calm inflammation and support healing
🌱 Stimulate tissue regeneration and cell growth
🩸 Promote angiogenesis for new, healthy blood vessels
The exosmart™ solution:
⚡ Unmatched Concentration: Up to 3.0 x 10¹³ particles/mL
✅ Validated Purity: Follows MISEV2023 guidelines
🛡 Superior Safety: 100% autologous, eliminating immune reaction risks

Autologous, concentrated exosomes deliver precise cellular signaling to target the root of tissue damage. Experience the next level of regenerative therapy with exosmart™.

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