09/23/2025
WHAT ARE PPX™ Exosomes?
The human body contains more than 37 trillion cells. These intrinsic biological building blocks must communicate with each other and cooperate for the body to function. Cells interact through very small vesicles — tiny bubble-like packages that move signaling molecules and matter around within a cell and most importantly from neighboring cells.
When a cell releases these vesicles, they are referred to as extracellular vesicles, or EVs for short. One type of EV is the exosome. These nano-sized particles carry various biological materials including proteins, lipids, and genetic information like messenger RNA (mRNA) and microRNA (miRNA). The primary function of these exosomes is to transport their cargo from one cell to another, helping regulate physiological processes such as immune response, inflammation, tissue repair, and cellular regeneration in what biologists call the “paracrine effect.”
This high level cellular communication has made the study and exploitation of exosomes invaluable in the field of orthopaedics. Current studies demonstrate that an important mechanism of action of exosomes is deploying their cargo of microRNA, a class of noncoding small RNAs that are important regulators of musculoskeletal disease, into the area of pathology to turn on the healing processes and turn off the destructive mechanisms. The use of exosomes allows the benefits of Stem Cell Therapy without the logistical challenges associated with exogenous nucleated cell therapy.
Biotechnology company ZEO Scientifix™ has introduced Patient Pure X™ (PPX™) — a highly-concentrated autologous product that contains billions of bioactive proteins and growth factors extracted from your blood that can help your body’s natural ability to decrease cellular inflammation and promote tissue healing.
We now offer this treatment at the Zehr Center! Call us at 239-596-0100 for more info.