07/05/2025
Sharp Wave Transients in Neonates - Abnormal Negative Sharp Wave Transients
These appear as sharp waves or true spikes. They most commonly arise in the context of an abnormal EEG background for PMA. Although they may also appear in the familiar midtemporal, central, or centrotemporal locations, they may be heavily concentrated in one region or hemisphere, rather than being randomly or evenly distributed spatially. They may also be seen in atypical locations such as the frontal, midline vertex, or occipital regions. They may be much more abundant compared with physiologic negative sharp wave transients. Data for neonates who were assessed developmentally at 1 year or older indicate that negative sharp waves more frequent than 11 per hour for preterm and 13 per hour for term infants are abnormal (Biagioni et al., 1996b; Clancy and Spitzer, 1985; Karbowski and Nencka, 1980; Rowe et al., 1985; Scher et al., 1994a; Statz et al., 1982). Abnormal negative sharp EEG transients are more likely than physiologic negative sharp waves to recur in brief runs or trains (Clancy, 1989).
Source: Tsuchida TN, Wusthoff CJ, Shellhaas RA, Abend NS, Hahn CD, Sullivan JE, Nguyen S, Weinstein S, Scher MS, Riviello JJ, Clancy RR; American Clinical Neurophysiology Society Critical Care Monitoring Committee. American clinical neurophysiology society standardized EEG terminology and categorization for the description of continuous EEG monitoring in neonates: report of the American Clinical Neurophysiology Society critical care monitoring committee. J Clin Neurophysiol. 2013 Apr;30(2):161-73. doi: 10.1097/WNP.0b013e3182872b24. PMID: 23545767.