Sherrie Koenigseder, MSN, APRN, NP-C

Sherrie Koenigseder, MSN, APRN, NP-C Certified Family Nurse Practitioner since 2016 with an Autonomous APRN and RN license in Florida

01/11/2026

Post 4: Why Estrogen Fluctuations Make Anxiety Worse

Estrogen helps regulate neurotransmitters, including GABA.

In perimenopause, estrogen doesn’t steadily decline—it spikes and crashes. This instability can:

• Disrupt GABA signaling
• Increase nervous system reactivity
• Trigger anxiety, irritability, or panic

This explains why symptoms may worsen at certain points in the cycle.

01/11/2026

Post 3: The Progesterone–GABA Connection

Progesterone isn’t just a reproductive hormone—it plays a major role in brain calm.

Progesterone is converted into a compound that enhances GABA activity in the brain. As progesterone declines during perimenopause:

• GABA becomes less effective
• Anxiety and sleep issues increase
• Emotional regulation becomes harder

This is why many women notice anxiety or insomnia before periods change.

01/11/2026

Post 2: What Is GABA and Why Does It Matter?

GABA (gamma-aminobutyric acid) is your brain’s brake pedal.

It helps:
• Quiet racing thoughts
• Promote restful sleep
• Stabilize mood
• Reduce muscle tension
• Improve stress tolerance

When GABA is working well, you feel calm but alert—not sedated or numb.
When GABA signaling is weak, the brain stays in “fight-or-flight,” even when nothing is wrong.

01/10/2026

Perimenopause & Your Brain: A Calming Neurotransmitter Series

Post 1: Why You Suddenly Feel Anxious in Perimenopause

Many women enter perimenopause feeling calm, capable, and resilient—then suddenly feel anxious, overwhelmed, or “on edge.”

This isn’t personality.
It’s brain chemistry.

During perimenopause, hormone fluctuations directly affect the nervous system, especially your ability to stay calm and regulated.

One key player? GABA, your brain’s main calming neurotransmitter.
If anxiety feels new or different lately, there’s a biological reason—and it deserves attention.

What do you do for fun on a Friday night?
01/10/2026

What do you do for fun on a Friday night?


01/01/2026

My 2026 Commitments & Vision

In 2026, I’m committing to growth that is intentional, ethical, and sustainable.

✨ Personally: protecting my peace with strong boundaries so I can be present, healthy, and grounded for my family.

🩺 Professionally: continuing to grow Navarre Primary Care as an NP-led clinic that prioritizes prevention, education, and root-cause care—not rushed, symptom-only medicine.

🤍 Collectively: advocating for nurse practitioners through mentorship, precepting, leadership, and legislative involvement—because patient-centered care depends on empowered clinicians.

This year isn’t about doing more.
It’s about doing what matters—well, and with purpose.

— Sherrie Koenigseder, APRN

12/29/2025

Today, we remember and honor Dr. Loretta Ford on what would have been her 105th birthday. A veteran, nurse and academic, Dr. Ford made history by founding the nurse practitioner role alongside Dr. Henry Silver in 1965. Dr. Ford’s legacy lives on through the high-quality health care provided by NPs in nearly a billion patient visits annually. Learn more about this nursing legend: bit.ly/Remembering-Dr-Ford.

12/29/2025

⚡ What Is "Good Energy" by Dr. Casey Means About?

At its core, "Good Energy" teaches that most chronic diseases share one root problem: poor metabolic health.

When our cells can’t make energy efficiently, the body shows it through:

• Fatigue
• Brain fog
• Weight gain
• Hormone issues
• Inflammation
• Anxiety
• Chronic disease

💡 The solution isn’t more meds—it’s supporting cellular health through food, movement, sleep, stress regulation, and blood sugar balance. I have yet to meet a patient deficient in any medication.

Healthy cells = good energy = better health.

✅ A Simple “Good Energy” Checklist for Everyday Health

According to Dr. Casey Means, improving health doesn’t require perfection—just consistency.

✔️ Prioritize whole, real foods
✔️ Build meals around protein, fiber, and healthy fats
✔️ Reduce ultra-processed foods and added sugars
✔️ Keep blood sugar stable (avoid constant snacking)
✔️ Move your body daily (walks count!)
✔️ Build muscle with resistance training
✔️ Get morning sunlight
✔️ Protect sleep like it’s medicine
✔️ Manage stress (nervous system health matters)
✔️ Limit alcohol
✔️ Support gut health
✔️ Listen to your body—not just the scale

✨ Small daily choices compound into big health changes.

Your body wants to heal—it just needs the right environment.

12/29/2025

🧠🌸 Perimenopause & Neurodivergent Women: What’s the Connection?

For neurodivergent women, perimenopause can feel especially disruptive—and often confusing—because hormonal changes directly affect the brain.

Perimenopause is the hormonal transition (often starting in the late 30s–40s) when estrogen and progesterone begin to fluctuate. These hormones don’t just regulate periods—they play a major role in brain function, mood, focus, and sensory processing.

💡 Why perimenopause can hit neurodivergent women harder:

🧠 Hormones & the Brain Estrogen supports:
• Dopamine (focus, motivation, executive function)
• Serotonin (mood stability)
• GABA (calm and stress regulation)

When estrogen fluctuates or declines, existing neurodivergent traits can intensify.

⚡ Common Worsening Symptoms Neurodivergent women may notice:
• Increased ADHD symptoms (brain fog, poor focus, forgetfulness)
• Emotional dysregulation or mood swings
• Heightened anxiety or panic
• Sensory overload (noise, lights, crowds)
• Increased burnout and fatigue
• Sleep disruption
• Feeling “less resilient” to stress

🔁 Loss of Coping Capacity Many women unknowingly relied on estrogen to help compensate for:
• Executive function challenges
• Emotional regulation
• Social masking

As hormones shift, the systems that once helped you cope may no longer work—leading many women to feel like they’re “falling apart,” when in reality, their biology is changing.

❗ Often Misdiagnosed As:
• Anxiety disorder
• Depression
• “Just stress”
• Aging
• Burnout

✨ The Truth Nothing is “wrong” with you. Your brain isn’t failing. Your hormones are changing.

When we understand the intersection of neurodivergence and perimenopause, we can:
✔️ Normalize the experience
✔️ Avoid mislabeling
✔️ Provide better support
✔️ Personalize care

💚 Awareness is power. Understanding your hormones can help you reclaim clarity, confidence, and compassion for yourself.

If this resonates—you’re not alone, and help exists.

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Navarre, FL
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