11/25/2025
Degenerative joint diseases like osteoarthritis and intervertebral disc degeneration are conditions that affect millions of people worldwide, leading to pain and reduced mobility. These diseases remain incurable because current treatments manage symptoms rather than addressing the root cause.
A Yale study in the journal Nature Bone Research found that cytosolic phospholipase A2 (cPLA2) is an important enzyme. It plays a key role in inflammation and cartilage breakdown. The study suggests that cPLA2 could be a possible target for treating joint diseases.
Degenerative joint diseases like osteoarthritis and intervertebral disc degeneration are conditions that affect millions of people worldwide, leading to pain