
08/20/2025
Brain scans aren’t just for injuries.
They may also reveal how fast you’re aging, according to a recent study published in Nature Aging.
Scientists analyzed over 50,000 MRI scans and used AI to spot patterns that reflect biological brain aging—not just chronological age.
Features such as the thickness of the cerebral cortex, an area that controls language and thinking, and the volume of gray matter can predict the rate at which a person’s ability to think and remember will decline, as well as risk of frailty, disease, and death.
“Imaging offers unique, direct insights into the brain’s structural aging, providing information that blood-based or molecular biomarkers alone can’t capture,” Mahdi Moqri, a computational biologist at Harvard Medical School, told Nature.
The research is still in its early stages—it’s not ready for clinical use yet. But this breakthrough could help identify who is at risk for age-related cognitive decline and dementia years before symptoms appear.
Study: Ledford H. How fast are you ageing? Ordinary brain scans reveal the pace. Nature. 2025 Jul;643(8071):314-315. doi: 10.1038/d41586-025-02086-9. PMID: 40594931.