
10/06/2025
The Journal of Cell Biology's October issue is here! https://hubs.la/Q03Llkdm0
The cover image shows early postnatal mouse cortex with astrocytes (magenta) and their mitochondria (green) in a model of inhibited astrocytic mitochondrial fission. Astrocytes are key sculptors of postnatal brain development and self-organize into tiled domains with non-overlapping territories amongst astrocytic neighbors. Silencing mitochondrial fission via knock-down of Drp1 decreases mitochondrial localization to distal astrocyte processes, induces aberrant clustering of astrocytes, and disrupts astrocyte tiled organization in the developing postnatal mouse cortex. See Rodriguez Salazar et al. https://hubs.la/Q03Llfyw0